ACIB – Austrian Center of Industrial Biotechnology (98730)

  • 8010

    Petersgasse 14 Graz

    Austria

Organization profile

Profile Information

Mission and Vision As a section of biosciences (biotechnology) biocatalysis is a promising area in the field of technological developments that is marked by considerable investments in research and bears a great potential for economic growth. Since the early 80s of the past century Graz has strived to build up an internationally renowned scientific expertise on the basis of existing interdisciplinary contacts leading to a series of successes achieved in cooperation with industrial partners. The Research Centre for Applied Biocatalysis forms a unique platform of research for the most outstanding protagonists in the field of science and economy in Austria. The expertise concentrated in our centre makes us, also internationally, a pivot for applied research in the field of biocatalysis. We support the innovative power and compatibility of our partners by: a concentration of existing expertise, access to novel knowledge, an acceleration of the economic realisation. Environment The founding of the Centre proceeds on the following assumption: The establishment of the Centre will give rise to a focussing, concentration and multiplication of the competences of all partners which holds significant advantages for the partners with respect to their positions as research institutions or companies on the Austrian and international markets, improves the scientific and technological ranking of the R&D activities in the field of applied biocatalysis in an international comparison, creates an important long-term source for R&D potential for Austrian science and economy, can act as a motor of innovation in the field of applied biocatalysis within the Austrian technology network, may have multiple side effects on the labour market and in the field of company founding and -settlement, and makes Austria an attractive partner for international cooperations, especially within the EU. Biosciences are evolving as key areas of science and technology and are seen as important parts of future economic growth. Biocatalysis is part of this scientific domain, frequently crossing the interdisciplinary borderlines to physics as well as biology and medicine. The AB Centre is aiming at making these advanced methods available for economic exploitation by companies working in this field. It is a continuation of a well-established multidisciplinary network of experts based on the Christian Doppler Laboratory of Chiral Compounds, Enzymatic and Microbial Synthesis of the Austrian Industries AG (1989-1994) and the Special Research Programme (SFB) "Biocatalysis" of the Austrian Science Fund (1993-2003). With its centre of gravity in Graz, there will also be activities located in Vienna as well as involvement of international industrial partners. The AB Centre is designed to be developed into a contract RTD company and continued beyond the period subsidised by the K-plus programme. The centre will bring together the scientific strength in the field and important industrial partners situated in Upper Austria, Styria, other parts of Austria and abroad. Keywords: Biocatalytic synthesis; conversion of carbohydrates by enzyme technology; enzyme development and analytics Subject areas: Analytische Chemie; Biochemie; Biochemische Technologie; Biotechnologie; Chemische Technologie; Enzymtechnologie; Strukturchemie Co-operating partners: Austin Powders (Austria) BASF (Germany) BioCatalytics Europe (Austria), recently acquired by Codexis (U.S.A.) CIBA Life Sciences (Switzerland) DSM Fine Chemicals Linz (Austria) Eucodis (Austria) Henkel (Austria) Lactoprot (Austria) Lactosan (Austria) Sandoz (Austria) Vogelbusch (Austria) VTU Engineering (Austria) Institut für Analytische Chemie, Mikro- und Radiochemie, TU Graz (Austria) Institut für Biochemie, TU Graz (Austria) Institut für Biotechnologie und Bioprozesstechnik, TU Graz (Austria) Institut für Chemie, Uni Graz (Austria) Institut für Lebensmittelwissenschaften und- technologie, BOKU Wien (Austria) Institut für Molekulare Biotechnologie, TU Graz (Austria) Institut für Organische Chemie (Austria) Institut für Umweltbiotechnologie, TU Graz (Austria) Funded by: all partners (Austria and international) Province of Styria together with SFG (Austria) FFG (Austria) Short Description: Our work is focused on enzymes! Our researchers explore the methods developed in the sophisticated "biochemical laboratory" of living cells in order to use them for the industrial purposes like production of chemicals without harmful side-effects on the environment and on natural resources. Furthermore, the enzymes responsible for these processes (biocatalysts) are improved and adapted to new purposes.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Pichia Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Microbiota Medicine & Life Sciences
mandelonitrile lyase Medicine & Life Sciences
Bryophyta Medicine & Life Sciences
Genes Chemical Compounds
Sphagnopsida Medicine & Life Sciences
Synthetic Biology Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1990 2018

Aliphatic hydroxylation and epoxidation of capsaicin by Cytochrome P450 CYP505X

Migglautsch, A. K., Willim, M., Schweda, B., Glieder, A., Breinbauer, R. & Winkler, M. 31 Aug 2018 In : Tetrahedron. 74, p. 6199-6204

Research output: Contribution to journalArticle

A novel assay for the detection of carboxylic acid reductase (CAR) activity in whole cells

Schwendenwein, D., Ressmann, A. K., Mihovilovic, M. D., Bornscheuer, U. T., Dörr, M., Rudroff, F. & Winkler, M. 27 Aug 2018

Research output: Contribution to conferencePoster

Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases

Heckenbichler, K., Schweiger, A. K., Brandner, L. A., Binter, A., Toplak, M., Macheroux, P., Gruber, K. & Breinbauer, R. 2018 In : Angewandte Chemie (Weinheim) / International edition in English. 57, p. 7240 –7244

Research output: Contribution to journalArticle

Open Access

Activities 2004 2018

Scientific Manuscript Writing Workshop

Winkler, M. (Organiser)
15 Nov 201816 Nov 2018

Activity: Workshop, seminar or course (Participation in/Organisation of)

Biotech für Kinder

Winkler, M. (Speaker)
25 Jun 2018

Activity: Schools engagement

Carboxylic acid reductase enzymes (CARs)

Winkler, M. (Speaker)
3 Jul 2018

Activity: Science to scienceTalk at conference or symposium

Prizes

12th Congress on Anaerobic Digestion / Best Poster Award

Stefan Weiß (Recipient), 4 Nov 2010

Prize: Prizes / Medals / Awards

anaerobic digestion
congress

Award of Excellence 2009

Martin Trinker (Recipient), 1 Dec 2009

Prize: Prizes / Medals / Awards

Best Paper Award des FoSP TNW

Roland Weis (Recipient), 28 Jun 2005

Prize: Prizes / Medals / Awards

Press / Media

Vanille-Mandel-Aroma aus Bakterien

Margit Winkler

1/02/18

1 item of media coverage

Press/Media: Press / Media

Die Leber im Reagenzglas

Margit Winkler

18/03/13

1 media contribution

Press/Media: Press / Media

Projects 2002 2009

Structure Function Relationship of Redox Enzymes

Schreiner, U., Glieder, A., Wriessnegger, T., Petschacher, B., Höller, B. & Winkler, M.

1/07/0931/12/09

Project: Research project

Novel enzymes and their structural characterization

Ribitsch, D.

1/07/0931/12/09

Project: Research project