Chemoenzymatic synthesis of the cephalosporin intermediate 7-amino-3-alkenylcephem-4-carboxylic acid

Ferdinand Zepeck (Inventor), Herbert Schleich (Inventor), Klaus Totschnig (Inventor), Peter Remler (Inventor), Birgit Seisser (Inventor), Gernot Strohmeier (Inventor)

Research output: PatentResearch

Abstract

The invention relates to processes for the prepn. of 7-amino-3-alkenylcephem-4-carboxylic acid (I) and the compds. II and III by using the enzymes p-nitrobenzyl esterase and penicillin G amidase. The processes either start from the compd. I or the compd. of Formula III.
Original languageEnglish
Patent numberWO2015071493
IPCC12P35/00
Priority date18/11/13
Publication statusPublished - 21 May 2015

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amidase
Penicillin G
Patents and inventions
Cephalosporins
Carboxylic Acids
Enzymes
4-nitrobenzyl esterase

Keywords

  • p-nitrobenzyl esterase
  • penicillin G amidase
  • cephalosporine

Cite this

Zepeck, F., Schleich, H., Totschnig, K., Remler, P., Seisser, B., & Strohmeier, G. (2015). IPC No. C12P35/00. Chemoenzymatic synthesis of the cephalosporin intermediate 7-amino-3-alkenylcephem-4-carboxylic acid. (Patent No. WO2015071493).

Chemoenzymatic synthesis of the cephalosporin intermediate 7-amino-3-alkenylcephem-4-carboxylic acid. / Zepeck, Ferdinand (Inventor); Schleich, Herbert (Inventor); Totschnig, Klaus (Inventor); Remler, Peter (Inventor); Seisser, Birgit (Inventor); Strohmeier, Gernot (Inventor).

IPC No.: C12P35/00. Patent No.: WO2015071493.

Research output: PatentResearch

Zepeck, F, Schleich, H, Totschnig, K, Remler, P, Seisser, B & Strohmeier, G 2015, Chemoenzymatic synthesis of the cephalosporin intermediate 7-amino-3-alkenylcephem-4-carboxylic acid, Patent No. WO2015071493, IPC No. C12P35/00.
Zepeck, Ferdinand (Inventor) ; Schleich, Herbert (Inventor) ; Totschnig, Klaus (Inventor) ; Remler, Peter (Inventor) ; Seisser, Birgit (Inventor) ; Strohmeier, Gernot (Inventor). / Chemoenzymatic synthesis of the cephalosporin intermediate 7-amino-3-alkenylcephem-4-carboxylic acid. IPC No.: C12P35/00. Patent No.: WO2015071493.
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AU - Seisser, Birgit

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