High temperature polymer electrolyte membrane fuel cells are characterized as a resource-saving and energy-efficient technology for heat and power generation. In MEA Power an inexpensive membrane electrode assembly (greater Euro 0.60 / cm2), which enables an intended lifetime of 80,000 hours under real operating conditions will be produced in laboratory scale. For this purpose, support materials will be functionalized, active platinum transition metal catalyst will be synthesized and the electrolyte will be immobilized in the active layer. The lifetime of the fabricated MEA will be determined by means of accelerated stress tests and further optimized. To support these activities, a translation of the measured results in a scalable simulation methodology will be done, to simulate the operation of an HT-PEMFC under steady state and transient operating conditions, resulting in an optimized HT-PEM stack.