Anton Glieder

Ao.Univ.-Prof. Mag.rer.nat. Dr.rer.nat.

1995 …2021
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Research Output 1996 2019

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2019

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., 2019, In : Biocatalysis and Agricultural Biotechnology. 17, p. 525-528 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
ibuprofen
Hydroxylation
Pichia pastoris
Biocatalysts
Pichia

Methanol Independent Expression by Pichia Pastoris Employing De-repression Technologies

Fischer, J. E., Hatzl, A-M., Weninger, A., Schmid, C. & Glieder, A., 2019, In : Journal of visualized experiments . 2019, 143, e58589.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Methanol
Technology
Bioreactors
Carbon
2018

Aliphatic hydroxylation and epoxidation of capsaicin by Cytochrome P450 CYP505X

Migglautsch, A. K., Willim, M., Schweda, B., Glieder, A., Breinbauer, R. & Winkler, M., 31 Aug 2018, In : Tetrahedron. 74, p. 6199-6204

Research output: Contribution to journalArticleResearchpeer-review

Construction of a cellulose-metabolizing Komagataella phaffii (Pichia pastoris) by co-expressing glucanases and β-glucosidase

Kickenweiz, T., Glieder, A. & Wu, J. C., 2018, In : Applied Microbiology and Biotechnology. 102, 3, p. 1297-1306

Research output: Contribution to journalArticleResearchpeer-review

Glucosidases
Pichia
Cellulose
Cellobiose
Cellulases

Engineered bidirectional promoters enable rapid multi-gene co-expression optimization

Vogl, T., Kickenweiz, T., Pitzer, J., Sturmberger, L., Weninger, A., Biggs, B. W., Köhler, E-M., Baumschlager, A., Fischer, J. E., Hyden, P., Wagner, M., Baumann, M., Borth, N., Geier, M., Ajikumar, P. K. & Glieder, A., 4 Sep 2018, In : Nature Communications. 9, 1, p. 3589

Research output: Contribution to journalArticleResearchpeer-review

genes
Synthetic Biology
Libraries
Genes
Metabolic Networks and Pathways

Methanol independent induction in Pichia pastoris by simple derepressed overexpression of single transcription factors

Vogl, T., Sturmberger, L., Fauland, P. C., Hyden, P., Fischer, J. E., Schmid, C., Thallinger, G. G., Geier, M. & Glieder, A., 1 Apr 2018, In : Biotechnology and Bioengineering. 115, 4, p. 1037-1050

Research output: Contribution to journalArticleResearchpeer-review

Transcription factors
Pichia
Methanol
Transcription Factors
Carbon

Parallelized biocatalytic scanning probe lithography for the additive fabrication of conjugated polymer structures

Hosford, J., Valles, M., Krainer, F. W., Glieder, A. & Wong, L. S., 2018, In : Nanoscale. 10, 15, p. 7185-7193 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Conjugated polymers
Lithography
Scanning
Fabrication
Polymers

Production of Hydroxynitrile Lyase from Davallia tyermannii (DtHNL) in Komagataella phaffii and Its Immobilization as a CLEA to Generate a Robust Biocatalyst

Lanfranchi, E., Grill, B., Raghoebar, Z., Van Pelt, S., Sheldon, R. A., Steiner, K., Glieder, A. & Winkler, M., 2018, In : ChemBioChem. 19, 4, p. 312-316 10.1002/cbic.201700419.

Research output: Contribution to journalArticleResearchpeer-review

mandelonitrile lyase
Immobilization
Enzymes
Ferns
Agrochemicals

The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases

Fiorentini, F., Hatzl, A-M., Schmidt, S., Savino, S., Glieder, A. & Mattevi, A., 2018, In : Biochemistry. 57, 48, p. 6701-6714

Research output: Contribution to journalArticleResearchpeer-review

Mixed Function Oxygenases
Plasticity
Hydroxylation
lauric acid
Substrates
2017

Cloning and upscale production of monoamine oxidase N (MAO-N D5) by Pichia pastoris

Markošová, K., Camattari, A., Rosenberg, M., Glieder, A., Turner, N. J. & Rebroš, M., 2017, In : Biotechnology Letters. https://doi.org/10.1007/s10529-017-2450-y.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Monoamine Oxidase
Organism Cloning
Enzymes
Clone Cells

Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

Lanfranchi, E., Pavkov-Keller, T., Koehler, E-M., Diepold, M., Steiner, K., Darnhofer, B., Hartler, J., Van Den Bergh, T., Joosten, H-J., Gruber-Khadjawi, M., Thallinger, G. G., Birner-Gruenberger, R., Gruber, K., Winkler, M. & Glieder, A., 10 May 2017, In : Scientific reports. 7, 46738.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
mandelonitrile lyase
Enzymes
Biocatalysis
Ferns
Crystallography

Erratum: Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

Lanfranchi, E., Pavkov-Keller, T., Koehler, E-M., Diepold, M., Steiner, K., Darnhofer, B., Hartler, J., Bergh, T. V. D., Joosten, H-J., Gruber-Khadjawi, M., Thallinger, G. G., Birner-Gruenberger, R., Gruber, K., Winkler, M. & Glieder, A., 26 May 2017, In : Scientific reports. 7, 46834.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
mandelonitrile lyase
Enzymes

Expanding the CRISPR/Cas9 toolkit for Pichia pastoris with efficient donor integration and alternative resistance markers

Weninger, A., Fischer, J., Raschmanová, H., Kniely, C., Vogl, T. & Glieder, A., 1 Nov 2017, In : Journal of Cellular Biochemistry.

Research output: Contribution to journalArticleResearchpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
Pichia
Homologous Recombination
Guide RNA
Genes

Pichia pastoris Alcohol Oxidase 1 (AOX1) Core Promoter Engineering by High Resolution Systematic Mutagenesis

Portela, R. M. C., Vogl, T., Ebner, K., Oliveira, R. & Glieder, A., 10 Nov 2017, In : Biotechnology Journal. 10.1002/biot.201700340.

Research output: Contribution to journalArticleResearchpeer-review

alcohol oxidase
Pichia
5' Untranslated Regions
Mutagenesis
Mutation

Synthetic Core Promoters as Universal Parts for Fine-Tuning Expression in Different Yeast Species

Portela, R. M. C., Vogl, T., Kniely, C., Fischer, J. E., Oliveira, R. & Glieder, A., 17 Mar 2017, In : ACS Synthetic Biology . 6, 3, p. 471-484 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthetic Biology
Gene expression
Yeast
Tuning
Yeasts
2016

A Toolbox of Diverse Promoters Related to Methanol Utilization: Functionally Verified Parts for Heterologous Pathway Expression in Pichia pastoris

Vogl, T., Sturmberger, L., Kickenweiz, T., Wasmayer, R., Schmid, C., Hatzl, A-M., Gerstmann, M. A., Pitzer, J., Wagner, M., Thallinger, G. G., Geier, M. & Glieder, A., 19 Feb 2016, In : ACS Synthetic Biology . 5, 2, p. 172-86 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Methanol
alcohol oxidase
Genes
Biosynthetic Pathways

Biotechnological advances towards an enhanced peroxidase production in Pichia pastoris

Krainer, F. W., Gerstmann, M. A., Darnhofer, B., Birner-Gruenberger, R. & Glieder, A., 10 Sep 2016, In : Journal of Biotechnology. 233, p. 181-9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Horseradish Peroxidase
Peroxidase
Enzymes
Methanol

Combinatorial optimization of CRISPR/Cas9 expression enables precision genome engineering in the methylotrophic yeast Pichia pastoris

Weninger, A., Hatzl, A-M., Schmid, C., Vogl, T. & Glieder, A., 10 Oct 2016, In : Journal of Biotechnology. 235, p. 139-49 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
Pichia
Guide RNA
RNA Polymerase II
Yeasts

Pichia pastoris mutants as host strains for efficient secretion of recombinant Branched Chain Aminotransferase (BCAT)

Weinhandl, K., Ballach, M., Winkler, M., Mudassar, A., Glieder, A., Birner-Gruenberger, R., Fotheringham, I. & Escalettes, F., 2016, In : Journal of Biotechnology. 235, p. 84-91 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Glycosylation
Pichia
Amino acids
Proteins
Amino Acids

Recombinant production of a peroxidase-protein G fusion protein in Pichia pastoris

Krainer, F., Darnhofer, B., Birner-Gruenberger, R. & Glieder, A., 10 Feb 2016, In : Journal of Biotechnology. 219, p. 24-27 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Horseradish Peroxidase
Peroxidase
Proteins
Isoenzymes

Synergism of proteomics and mRNA sequencing for enzyme discovery

Sturmberger, L., Wallace, P. W., Glieder, A. & Birner-Gruenberger, R., 10 Oct 2016, In : Journal of Biotechnology. 235, p. 132-8 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Proteomics
Messenger RNA
Enzymes
Protein Databases
Technology
2015

An updated view on horseradish peroxidases: recombinant production and biotechnological applications.

Krainer, F. & Glieder, A., 2015, In : Applied Microbiology and Biotechnology. 99, 4, p. 1611-1625

Research output: Contribution to journalArticleResearchpeer-review

A toolbox of endogenous and heterologous nuclear localization sequences for the methylotrophic yeast Pichia pastoris

Weninger, A., Glieder, A. & Vogl, T., Nov 2015, In : FEMS yeast research. 15, 7, 4 p., fov082.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Yeasts
Proteins
Eukaryota
CRISPR-Associated Proteins

Bioprospecting for Hydroxynitrile Lyases by Blue Native PAGE Coupled HCN Detection

Lanfranchi, E., Köhler, E-M., Darnhofer, B., Steiner, K., Birner-Grünberger, R., Glieder, A. & Winkler, M., 2015, In : Current biotechnology. 4, 2, p. 111-117

Research output: Contribution to journalArticleResearchpeer-review

Compact multi-enzyme pathways in P. pastoris

Geier, M., Fauland, P. C., Vogl, T. & Glieder, A., 2015, In : Chemical Communications. 15, 51;9, p. 1643-1646

Research output: Contribution to journalArticleResearchpeer-review

Engineering Pichia pastoris for improved NADH regeneration: A novel chassis strain for whole-cell catalysis

Geier, M., Brandner, C., Strohmeier, G. A., Hall, M., Hartner, F. S. & Glieder, A., 2015, In : Beilstein Journal of Organic Chemistry . 11, p. 1741-8 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Chassis
NAD
Catalysis
Methanol
formaldehyde transketolase

Optimizing cofactor availability for the production of recombinant heme peroxidase in Pichia pastoris.

Krainer, F., Capone, S., Jäger, M., Vogl, T., Gerstmann, M. A., Glieder, A., Herwig, C. & Spadiut, O., 2015, In : Microbial cell factories . 14, 4, p. 1-9

Research output: Contribution to journalArticleResearchpeer-review

Recombinant Expression of Trichoderma reesei Cel61A in Pichia pastoris: Optimizing Yield and N-terminal Processing

Tanghe, M., Danneels, B., Camattari, A., Glieder, A., Vandenberghe, I., Devreese, B., Stals, I. & Desmet, T., Dec 2015, In : Molecular biotechnology. 57, 11-12, p. 1010-7 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Trichoderma
Pichia
Enzymes
Mating Factor
Polysaccharides

Restriction site free cloning (RSFC) plasmid family for seamless, sequence independent cloning in Pichia pastoris

Vogl, T., Ahmad, M., Krainer, F., Schwab, H. & Glieder, A., 2015, In : Microbial cell factories . 14, p. 1-15

Research output: Contribution to journalArticleResearchpeer-review

2014

Carbon source dependent promoters in yeasts

Weinhandl, K., Winkler, M., Glieder, A. & Camattari, A., 2014, In : Microbial cell factories . 13, p. 5-21

Research output: Contribution to journalArticleResearchpeer-review

Cofactor Specificity Engineering of Streptococcus mutans NADH Oxidase 2 for NAD (P)+ Regeneration in Biocatalytic Oxidations

Petschacher, B., Staunig, N., Mueller, M., Schuermann, M., Mink, D., Wildemann, S., Gruber, K. & Glieder, A., 2014, In : Computational and Structural Biotechnology Journal. 9, 14, p. 1-11

Research output: Contribution to journalArticleResearchpeer-review

Enantioselective trans-dihydroxylation of aryl olefins by cascade biocatalysis with recombinant escherichia coli coexpressing monooxygenase and epoxide hydrolase

Wu, S., Chen, Y., Xu, Y., Glieder, A. & Li, Z., 2014, In : ACS Catalysis. 4, 2, p. 409-420

Research output: Contribution to journalArticleResearchpeer-review

Microbials for the production of monoclonal antibodies and antibody fragments

Spadiut, O., Capone, S., Krainer, F., Glieder, A. & Herwig, C., 2014, In : Trends in biotechnology. 32, 1, p. 54-60

Research output: Contribution to journalArticleResearchpeer-review

Peroxidase gene discovery from the horseradish transcriptome

Näätsaari, L., Krainer, F., Schubert, M., Glieder, A. & Thallinger, G., 2014, In : BMC Genomics . 15, 1, p. 227-227

Research output: Contribution to journalArticleResearchpeer-review

PRODUCTION OF RECOMBINANT HUMAN ALDEHYDE OXIDASE IN E. COLI AND OPTIMIZATION OF ITS APPLICATION FOR PREPARATIVE SYNTHESIS OF OXIDIZED DRUG METABOLITES

Rodrigues, D., Kittelmann, M., Eggimann, F., Bachler, T., Abad, S., Camattari, A., Glieder, A., Winkler, M. & Lütz, S., 2014, In : ChemCatChem. 6, 4, p. 1028-1042

Research output: Contribution to journalArticleResearchpeer-review

Purification and basic biochemical characterization of 19 recombinant plant peroxidase isoenzymes produced in Pichia pastoris.

Krainer, F., Pletzenauer, R., Rossetti, L., Herwig, C., Glieder, A. & Spadiut, O., 2014, In : Protein expression and purification. 95, p. 104-112

Research output: Contribution to journalArticleResearch

Synergistic modular promoter and gene optimization to push cellulase secretion by Pichia pastoris beyond existing benchmarks

Mellitzer, A., Ruth, C., Gustafson, C., Welch, M., Birner-Gruenberger, R., Weis, R., Purkarthoer, T. & Glieder, A., 2014, In : Journal of Biotechnology. 191, p. 187-195

Research output: Contribution to journalArticleResearchpeer-review

Synthetic Core Promoters for Pichia pastoris

Vogl, T., Ruth, C., Pitzer, J., Kickenweiz, T. & Glieder, A., 2014, In : ACS Synthetic Biology . 3, 3, p. 188–191

Research output: Contribution to journalArticleResearchpeer-review

Thermostability improvement of endoglucanase Cel7B from Hypocrea pseudokoningii

Mitrovic, A., Flicker, K., Steinkellner, G., Gruber, K., Reisinger, C., Schirrmacher, C., Camattari, A. & Glieder, A., 2014, In : Journal of molecular catalysis / B. 103, p. 16-23

Research output: Contribution to journalArticleResearchpeer-review

Towards improved membrane protein production in Pichia pastoris: general and specific transcriptional response to membrane protein overexpression

Vogl, T., Thallinger, G., Zellnig, G., Drew, D., Cregg, J., Glieder, A. & Freigaßner, M. E., 2014, In : New biotechnology. 31, 6, p. 538-552

Research output: Contribution to journalArticleResearchpeer-review

2013

Double site saturation mutagenesis of the human cytochrome P450 2D6 results in regioselective steroid hydroxylation

Geier, M., Braun, A., Fladischer, P., Stepniak, P., Rudroff, F., Hametner, C., Mihovilovic, M. & Glieder, A., 2013, In : The FEBS journal. 280, 13, p. 3094-108

Research output: Contribution to journalArticleResearchpeer-review

First functional expression of cytochrome P450 3A4 in Pichia pastoris

Geier, M., Schmid, C. & Glieder, A., 2013, In : Chimica Oggi. 31, 3, p. 24-27

Research output: Contribution to journalArticleResearch

Knockout of an endogenous mannosyltransferase increases the homogeneity of glycoproteins produced in Pichia pastoris

Krainer, F., Gmeiner, C., Neutsch, L., Windwarder, M., Pletzenauer, R., Herwig, C., Altmann, F., Glieder, A. & Spadiut, O., 2013, In : Scientific reports. 3, p. 3279-3291

Research output: Contribution to journalArticleResearchpeer-review

RECENT DEVELOPMENTS IN HYDROXYNITRILE LYASES FOR INDUSTRIAL BIOTECHNOLOGY

Lanfranchi, E., Steiner, K., Glieder, A., Hajnal, I., Sheldon, R. A., van Pelt, S. & Winkler, M., 2013, In : Recent patents on biotechnology. 7, 3, p. 197-206

Research output: Contribution to journalArticleResearchpeer-review

Screening for cytochrome P450 expression in Pichia pastoris whole cells by P450-carbon monoxide complex determination

Gudiminchi, R. K., Geier, M., Glieder, A. & Camattari, A., Jan 2013, In : Biotechnology Journal. 8, 1, p. 146-152 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Carbon Monoxide
Cytochrome P-450 Enzyme System
Yeasts
Cytochrome P-450 CYP2D6
2012

A NOVEL MULTI-ENZYMATIC ASSAY FOR TRANSAMINASE ACTIVITY: HIGH THROUGHPUT SCREENING APPLICATIONS IN PICHIA PASTORIS

Weinhandl, K., Winkler, M., Glieder, A. & Camattari, A., 2012, In : Tetrahedron. 68, p. 7586-7590

Research output: Contribution to journalArticleResearchpeer-review

Deletion of the Pichia pastoris KU70 homologue facilitates platform strain generation for gene expression and synthetic biology

Näätsaari, L., Mistlberger, B., Ruth, C., Hajek, T., Hartner, F. S. & Glieder, A., 2012, In : PLoS ONE. 7, 6, p. e39720

Research output: Contribution to journalArticleResearchpeer-review

Synthetic Biology
synthetic biology
Pichia pastoris
Pichia
Gene expression

Expression of lignocellulolytic enzymes in Pichia pastoris

Mellitzer, A., Weis, R., Glieder, A. & Flicker, K., 14 May 2012, In : Microbial cell factories . 11, p. 61 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Enzymes
Cellulose 1,4-beta-Cellobiosidase
Genes
alcohol oxidase

Expression of recombinant human flavin monooxygenase and moclobemide-N-oxide synthesis on multi-mg scale

Hanlon, S. P., Camattari, A., Abad, S., Glieder, A., Wirz, B., Kittelmann, M., Lütz, S. & Winkler, M., 2012, In : Chemical Communications. 48, 48, p. 6001-6003 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Moclobemide
Mixed Function Oxygenases
Oxides
Drug Compounding
Escherichia coli

MuteinDB: the mutein database linking substrates, products and enzymatic reactions directly with genetic variants of enzymes

Braun, A., Halwachs, B., Geier, M., Weinhandl, K., Guggemos, M., Marienhagen, J., Ruff, A. J., Schwaneberg, U., Torres Pazmiño, D. E., Rabin, V., Thallinger, G. & Glieder, A., 2012, In : Database - The Journal of Biological Databases and Curation . p. bas028-bas028

Research output: Contribution to journalArticleResearchpeer-review