Anton Glieder

Ao.Univ.-Prof. Mag.rer.nat. Dr.rer.nat.

1995 …2021
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Research Output 1996 2019

2019

Capsaicin Metabolite Synthesis by Fungal Cytochrome P450

Willim, M., Bachler, T., Schweda, B., Migglautsch, A. K., Glieder, A., Breinbauer, R. & Winkler, M., 14 Feb 2019.

Research output: Contribution to conferencePosterResearch

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., 2019, In : Biocatalysis and Agricultural Biotechnology. 17, p. 525-528 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
ibuprofen
Hydroxylation
Pichia pastoris
Biocatalysts
Pichia

Methanol Independent Expression by Pichia Pastoris Employing De-repression Technologies

Fischer, J. E., Hatzl, A-M., Weninger, A., Schmid, C. & Glieder, A., 2019, In : Journal of visualized experiments . 2019, 143, e58589.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Methanol
Technology
Bioreactors
Carbon
2018

Aliphatic hydroxylation and epoxidation of capsaicin by Cytochrome P450 CYP505X

Migglautsch, A. K., Willim, M., Schweda, B., Glieder, A., Breinbauer, R. & Winkler, M., 31 Aug 2018, In : Tetrahedron. 74, p. 6199-6204

Research output: Contribution to journalArticleResearchpeer-review

Combinatorial optimization strategies to increase Human P450 catalytic Activity in whole cell

Weninger, A., Alkofer, A., Schmid, C., Bitter, J., Volpini de Maestri, A., Pranjic, M., Winkler, M. & Glieder, A., Sep 2018.

Research output: Contribution to conferencePosterResearch

Construction of a cellulose-metabolizing Komagataella phaffii (Pichia pastoris) by co-expressing glucanases and β-glucosidase

Kickenweiz, T., Glieder, A. & Wu, J. C., 2018, In : Applied Microbiology and Biotechnology. 102, 3, p. 1297-1306

Research output: Contribution to journalArticleResearchpeer-review

Glucosidases
Pichia
Cellulose
Cellobiose
Cellulases

Engineered bidirectional promoters enable rapid multi-gene co-expression optimization

Vogl, T., Kickenweiz, T., Pitzer, J., Sturmberger, L., Weninger, A., Biggs, B. W., Köhler, E-M., Baumschlager, A., Fischer, J. E., Hyden, P., Wagner, M., Baumann, M., Borth, N., Geier, M., Ajikumar, P. K. & Glieder, A., 4 Sep 2018, In : Nature Communications. 9, 1, p. 3589

Research output: Contribution to journalArticleResearchpeer-review

genes
Synthetic Biology
Libraries
Genes
Metabolic Networks and Pathways

Erratum to: Engineered bidirectional promoters enable rapid multi-gene co-expression optimization (Nature Communications, (2018), 9, 1, (3589), 10.1038/s41467-018-05915-w)

Vogl, T., Kickenweiz, T., Pitzer, J., Sturmberger, L., Weninger, A., Biggs, B. W., Köhler, E. M., Baumschlager, A., Fischer, J. E., Hyden, P., Wagner, M., Baumann, M., Borth, N., Geier, M., Ajikumar, P. K. & Glieder, A., 1 Dec 2018, In : Nature Communications. 9, 1, 4566.

Research output: Contribution to journalComment/debateResearchpeer-review

files
genes
Publications
Genes
communication

Humane Enzyme für die Organische Synthese

Winkler, M., Geier, M., Hanlon, S. P., Nidetzky, B. & Glieder, A., 2018, In : Angewandte Chemie. 130, p. 13592-13610

Research output: Contribution to journalReview articleResearchpeer-review

Human Enzymes for Organic Synthesis

Winkler, M., Geier, M., Hanlon, S. P., Nidetzky, B. & Glieder, A., 2018, In : Angewandte Chemie / International Edition . 57, 41, p. 13406-13423 18 p.

Research output: Contribution to journalReview articleResearchpeer-review

Enzymes
Pharmaceutical Preparations
Xenobiotics
Metabolites
Metabolism

Implementing CRISPR-Cas technologies in conventional and non-conventional yeasts: Current state and future prospects

Raschmanová, H., Weninger, A., Glieder, A., Kovar, K. & Vogl, T., 1 May 2018, In : Biotechnology Advances. 36, 3, p. 641-665 25 p.

Research output: Contribution to journalReview articleResearchpeer-review

CRISPR-Cas Systems
Clustered Regularly Interspaced Short Palindromic Repeats
Yeast
Saccharomyces cerevisiae
Yeasts

Methanol independent induction in Pichia pastoris by simple derepressed overexpression of single transcription factors

Vogl, T., Sturmberger, L., Fauland, P. C., Hyden, P., Fischer, J. E., Schmid, C., Thallinger, G. G., Geier, M. & Glieder, A., 1 Apr 2018, In : Biotechnology and Bioengineering. 115, 4, p. 1037-1050

Research output: Contribution to journalArticleResearchpeer-review

Transcription factors
Pichia
Methanol
Transcription Factors
Carbon

Parallelized biocatalytic scanning probe lithography for the additive fabrication of conjugated polymer structures

Hosford, J., Valles, M., Krainer, F. W., Glieder, A. & Wong, L. S., 2018, In : Nanoscale. 10, 15, p. 7185-7193 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Conjugated polymers
Lithography
Scanning
Fabrication
Polymers

Production of Hydroxynitrile Lyase from Davallia tyermannii (DtHNL) in Komagataella phaffii and Its Immobilization as a CLEA to Generate a Robust Biocatalyst

Lanfranchi, E., Grill, B., Raghoebar, Z., Van Pelt, S., Sheldon, R. A., Steiner, K., Glieder, A. & Winkler, M., 2018, In : ChemBioChem. 19, 4, p. 312-316 10.1002/cbic.201700419.

Research output: Contribution to journalArticleResearchpeer-review

mandelonitrile lyase
Immobilization
Enzymes
Ferns
Agrochemicals

The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases

Fiorentini, F., Hatzl, A-M., Schmidt, S., Savino, S., Glieder, A. & Mattevi, A., 2018, In : Biochemistry. 57, 48, p. 6701-6714

Research output: Contribution to journalArticleResearchpeer-review

Mixed Function Oxygenases
Plasticity
Hydroxylation
lauric acid
Substrates
2017

Chemicals made by Pichia pastoris

Glieder, A., 1 Nov 2017.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Cloning and upscale production of monoamine oxidase N (MAO-N D5) by Pichia pastoris

Markošová, K., Camattari, A., Rosenberg, M., Glieder, A., Turner, N. J. & Rebroš, M., 2017, In : Biotechnology Letters. https://doi.org/10.1007/s10529-017-2450-y.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Monoamine Oxidase
Organism Cloning
Enzymes
Clone Cells

Combinatorial optimization strategies to increase Human P450 catalytic Activity in whole cell Biotransformations

Weninger, A., Alkofer, A., Schmid, C., Pranjic, M., Winkler, M. & Glieder, A., Jul 2017.

Research output: Contribution to conferencePosterResearch

Concurrent optimization strategies for high level protein production: Process, strain and expression engineering

Weninger, A., Alkofer, A., Schmid, C., Höppel, E., Winkler, M. & Glieder, A., Jun 2017.

Research output: Contribution to conferencePosterResearch

Cytochrome P450 CYP505 mutants for biooxidations of active pharmaceutical ingredients

Bachler, T., Weninger, A., Glieder, A. & Winkler, M., 5 Sep 2017.

Research output: Contribution to conferencePosterResearch

Cytochrome P450 CYP505 mutants for biooxidations of active pharmaceutical ingredients

Bachler, T., Weninger, A., Glieder, A. & Winkler, M., 21 Nov 2017.

Research output: Contribution to conferencePosterResearch

Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

Lanfranchi, E., Pavkov-Keller, T., Koehler, E-M., Diepold, M., Steiner, K., Darnhofer, B., Hartler, J., Van Den Bergh, T., Joosten, H-J., Gruber-Khadjawi, M., Thallinger, G. G., Birner-Gruenberger, R., Gruber, K., Winkler, M. & Glieder, A., 10 May 2017, In : Scientific reports. 7, 46738.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
mandelonitrile lyase
Enzymes
Biocatalysis
Ferns
Crystallography

Erratum: Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

Lanfranchi, E., Pavkov-Keller, T., Koehler, E-M., Diepold, M., Steiner, K., Darnhofer, B., Hartler, J., Bergh, T. V. D., Joosten, H-J., Gruber-Khadjawi, M., Thallinger, G. G., Birner-Gruenberger, R., Gruber, K., Winkler, M. & Glieder, A., 26 May 2017, In : Scientific reports. 7, 46834.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
mandelonitrile lyase
Enzymes

Expanding the CRISPR/Cas9 toolkit for Pichia pastoris with efficient donor integration and alternative resistance markers

Weninger, A., Fischer, J., Raschmanová, H., Kniely, C., Vogl, T. & Glieder, A., 1 Nov 2017, In : Journal of Cellular Biochemistry.

Research output: Contribution to journalArticleResearchpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
Pichia
Homologous Recombination
Guide RNA
Genes

Heme Enzymes for Biocatalysis

Glieder, A., 6 Oct 2017.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Pichia pastoris Alcohol Oxidase 1 (AOX1) Core Promoter Engineering by High Resolution Systematic Mutagenesis

Portela, R. M. C., Vogl, T., Ebner, K., Oliveira, R. & Glieder, A., 10 Nov 2017, In : Biotechnology Journal. 10.1002/biot.201700340.

Research output: Contribution to journalArticleResearchpeer-review

alcohol oxidase
Pichia
5' Untranslated Regions
Mutagenesis
Mutation

Protein expression: Yeast or E. coli

Glieder, A., 6 Oct 2017.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Substrate specificity of CYP505X from Aspergillus fumigatus

Bachler, T., Alkofer, A., Gralewska, P., Weninger, A., Glieder, A., Breinbauer, R. & Winkler, M., 11 Jul 2017.

Research output: Contribution to conferencePosterResearch

Synthetic Core Promoters as Universal Parts for Fine-Tuning Expression in Different Yeast Species

Portela, R. M. C., Vogl, T., Kniely, C., Fischer, J. E., Oliveira, R. & Glieder, A., 17 Mar 2017, In : ACS Synthetic Biology . 6, 3, p. 471-484 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthetic Biology
Gene expression
Yeast
Tuning
Yeasts
2016

Access and use of fern hydroxynitrile lyase for biocatalysis

Glieder, A., Lanfranchi, E., Winkler, M., Gruber, K. & Pavkov-Keller, T., 28 Sep 2016.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

A new family of R-selective Hydroxynitrile lyases

Lanfranchi, E., Köhler, E-M., Diepold, M., Pavkov-Keller, T., Gruber, K., Steiner, K., Glieder, A. & Winkler, M., 11 Jul 2016.

Research output: Contribution to conferencePosterResearch

A new family of R-selective Hydroxynitrile lyases

Lanfranchi, E., Eva-Maria, K., Diepold, M., Pavkov-Keller, T., Gruber, K., Steiner, K., Glieder, A. & Winkler, M., 16 Nov 2016.

Research output: Contribution to conferencePosterResearch

A Toolbox of Diverse Promoters Related to Methanol Utilization: Functionally Verified Parts for Heterologous Pathway Expression in Pichia pastoris

Vogl, T., Sturmberger, L., Kickenweiz, T., Wasmayer, R., Schmid, C., Hatzl, A-M., Gerstmann, M. A., Pitzer, J., Wagner, M., Thallinger, G. G., Geier, M. & Glieder, A., 19 Feb 2016, In : ACS Synthetic Biology . 5, 2, p. 172-86 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Methanol
alcohol oxidase
Genes
Biosynthetic Pathways

Biotechnological advances towards an enhanced peroxidase production in Pichia pastoris

Krainer, F. W., Gerstmann, M. A., Darnhofer, B., Birner-Gruenberger, R. & Glieder, A., 10 Sep 2016, In : Journal of Biotechnology. 233, p. 181-9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Horseradish Peroxidase
Peroxidase
Enzymes
Methanol

Combinatorial optimization of CRISPR/Cas9 expression enables precision genome engineering in the methylotrophic yeast Pichia pastoris

Weninger, A., Hatzl, A-M., Schmid, C., Vogl, T. & Glieder, A., 10 Oct 2016, In : Journal of Biotechnology. 235, p. 139-49 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
Pichia
Guide RNA
RNA Polymerase II
Yeasts

COMPACT AND OPTIMIZED METABOLIC PATHWAY DESIGN IN PICHIA PASTORIS

Geier, M., Glieder, A. & Fauland, P., 6 May 2016, IPC No. C12N 15/ 09 A I, Patent No. WO2016066711, Priority date 28 Oct 2014, Priority No. EP20140190702

Research output: PatentResearch

Pichia
Metabolic Networks and Pathways
Yeasts
Gene Expression

Concurrent optimization strategies for high level protein production: Protein, strain and expression engineering

Weninger, A., Alkofer, A., Wimmer, R., Höppel, E., Eichmann, J. P-R., Schmid, C., Winkler, M. & Glieder, A., 22 Sep 2016.

Research output: Contribution to conferencePosterResearch

Expression of fungal cytochrome P450 variants in E. coli and their validation for API metabolite synthesis

Bachler, T., Eichmann, J. P-R., Weninger, A., Hammer, K., Tunjic, S., Glieder, A., Breinbauer, R. & Winkler, M., 12 Sep 2016.

Research output: Contribution to conferencePosterResearch

NEW HYDROXYNITRILE LYASES

Glieder, A., Lanfranchi, E., Steiner, K., Pavkov-Keller, T., Diepold, M. & Winkler, M., Feb 2016, Patent No. WO2016020528 (A1)

Research output: PatentResearch

Pichia pastoris mutants as host strains for efficient secretion of recombinant Branched Chain Aminotransferase (BCAT)

Weinhandl, K., Ballach, M., Winkler, M., Mudassar, A., Glieder, A., Birner-Gruenberger, R., Fotheringham, I. & Escalettes, F., 2016, In : Journal of Biotechnology. 235, p. 84-91 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Glycosylation
Pichia
Amino acids
Proteins
Amino Acids

Polypeptides having xylanase activity with a high conversion rate of xylose-containing polysaccharides

REISINGER, CHRISTOPH., Gamauf, C., KRAUS, MICHAEL., UNTERSTRASSER, ISABEL., MITROVIC, ALEKSANDRA. & Glieder, A., 9 Mar 2016, IPC No. C12N 9/ 24 A I, Patent No. EP2993230, Priority date 2 Sep 2014, Priority No. EP20140003017

Research output: PatentResearch

Xylose
Polysaccharides
Nucleic acid sequences
Peptides
Patents and inventions

Recombinant production of a peroxidase-protein G fusion protein in Pichia pastoris

Krainer, F., Darnhofer, B., Birner-Gruenberger, R. & Glieder, A., 10 Feb 2016, In : Journal of Biotechnology. 219, p. 24-27 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Horseradish Peroxidase
Peroxidase
Proteins
Isoenzymes

Refined Pichia pastoris reference genome sequence

Sturmberger, L., Chappell, T., Geier, M., Krainer, F., Day, K. J., Vide, U., Trstenjak, S., Schiefer, A., Richardson, T., Soriaga, L., Darnhofer, B., Birner-Gruenberger, R., Glick, B. S., Tolstorukov, I., Cregg, J., Madden, K. & Glieder, A., 10 Oct 2016, In : Journal of Biotechnology. 235, p. 121-131 11 p.

Research output: Contribution to journalReview articleResearchpeer-review

Pichia
Genes
Genome
Chromosomes
Open Reading Frames

Scent of bitter almond and a pinch of –omics: discovering a novel hydroxynitrile lyase

Lanfranchi, E., Pavkov-Keller, T., Steiner, K., Gruber, K., Winkler, M. & Glieder, A., 11 Oct 2016.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Synergism of proteomics and mRNA sequencing for enzyme discovery

Sturmberger, L., Wallace, P. W., Glieder, A. & Birner-Gruenberger, R., 10 Oct 2016, In : Journal of Biotechnology. 235, p. 132-8 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Proteomics
Messenger RNA
Enzymes
Protein Databases
Technology

Synthetic biology for organic syntheses

Wiltschi, B. & Glieder, A., 2016, Microwave-Assisted Polymerization. 46 ed. Royal Society of Chemistry, Vol. 2016-January. p. 165-179 15 p. (RSC Green Chemistry; vol. 2016-January, no. 46).

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Synthetic Biology
Synthetic Chemistry Techniques
Biosynthesis
Biological systems
Acids

Towards API Metabolite Synthesis by Fungal Cytochrome P450 variants

Bachler, T., Eichmann, J. P-R., Weninger, A., Glieder, A., Breinbauer, R. & Winkler, M., 16 Nov 2016.

Research output: Contribution to conferencePosterResearch

2015

(R)-selective hydroxynitrile lyase variants with a cupin fold having improved substrate scope and the use thereof

WIEDNER, ROMANA., STEINER, KERSTIN., Glieder, A. & SCHWAB, HELMUT., 16 Dec 2015, IPC No. C12P 13/ 00 A I, Patent No. EP2955225, Priority date 12 Jun 2014, Priority No. EP20140172216

Research output: PatentResearch

lyases
amino acid substitution

An updated view on horseradish peroxidases: recombinant production and biotechnological applications.

Krainer, F. & Glieder, A., 2015, In : Applied Microbiology and Biotechnology. 99, 4, p. 1611-1625

Research output: Contribution to journalArticleResearchpeer-review

A toolbox of endogenous and heterologous nuclear localization sequences for the methylotrophic yeast Pichia pastoris

Weninger, A., Glieder, A. & Vogl, T., Nov 2015, In : FEMS yeast research. 15, 7, 4 p., fov082.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Yeasts
Proteins
Eukaryota
CRISPR-Associated Proteins