Visualization-Combined Microbiome Detection (VCMD) method enable deep analyses of Central Venous Catheter Infections

Alexander Fuchs, Anastasia Bragina, Maria Sensen, Robert Krause, Gabriele Berg

Publikation: KonferenzbeitragPosterBegutachtung

Abstract

Biofilms, bacteria-protective exopolysaccharide layers, are ubiquitous in environment and can also be found in different medical indwelling devices. Biofilm formation on central venous catheters (CVCs) in many cases leads to CVC-related blood stream infections (CRBSI), which results in higher mortality rate and increased treatment costs.
The aim of our study was to investigate the CVC colonization patterns of removed catheters from patients who developed infection by applying Visualization-Combined Microbiome Detection (VCMD) method. VCDM includes fluorescence in situ hybridization (FISH) in combination with confocal laser scanning microscope (CLSM) as well as sequencing based microbiome analyses.
Originalspracheenglisch
PublikationsstatusVeröffentlicht - 2015
Veranstaltung2nd Theodor Escherich Symposium on Medical Microbiome Research - Medical University of Graz, Austria
Dauer: 19 Okt. 201519 Okt. 2015

Konferenz

Konferenz2nd Theodor Escherich Symposium on Medical Microbiome Research
OrtMedical University of Graz, Austria
Zeitraum19/10/1519/10/15

Fields of Expertise

  • Human- & Biotechnology

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