Visualization-Combined Microbiome Detection (VCMD) method enable deep analyses of Central Venous Catheter Infections

Alexander Fuchs, Anastasia Bragina, Maria Sensen, Robert Krause, Gabriele Berg

Research output: Contribution to conferencePoster

Abstract

Biofilms, bacteria-protective exopolysaccharide layers, are ubiquitous in environment and can also be found in different medical indwelling devices. Biofilm formation on central venous catheters (CVCs) in many cases leads to CVC-related blood stream infections (CRBSI), which results in higher mortality rate and increased treatment costs.
The aim of our study was to investigate the CVC colonization patterns of removed catheters from patients who developed infection by applying Visualization-Combined Microbiome Detection (VCMD) method. VCDM includes fluorescence in situ hybridization (FISH) in combination with confocal laser scanning microscope (CLSM) as well as sequencing based microbiome analyses.
Original languageEnglish
Publication statusPublished - 2015
Event2nd Theodor Escherich Symposium on Medical Microbiome Research - Medical University of Graz, Austria
Duration: 19 Oct 201519 Oct 2015

Conference

Conference2nd Theodor Escherich Symposium on Medical Microbiome Research
CityMedical University of Graz, Austria
Period19/10/1519/10/15

Fields of Expertise

  • Human- & Biotechnology

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