Synthetische Proteine: Protein Engineering mit nicht-kanonischen Aminosäuren

Natascha Hotz; Tanja Marzluf; Birgit Wiltschi

doi:10.1007/s12268-012-0146-3

Synthetische Proteine: Protein Engineering mit nicht-kanonischen Aminosäuren

Translated title of the contribution: Synthetic proteins: Protein engineering with non-canonical amino acids

Natascha Hotz, Tanja Marzluf, Birgit Wiltschi^*

^*Corresponding author for this work

Research output: Contribution to journal › Article

Abstract

Non-canonical amino acids as building blocks for protein biosynthesis facilitate modifications that go far beyond classical genetic engineering. Two complementary techniques allow either site-specific or residue-specific incorporation. Accordingly, the possible modifications range from atomic changes to the alteration of the overall biophysical characteristics of a protein. In this article, we present the state of the art of this new protein engineering approach.

Translated title of the contribution	Synthetic proteins: Protein engineering with non-canonical amino acids
Original language	German
Pages (from-to)	96-99
Number of pages	4
Journal	Biospektrum
Volume	18
Issue number	1
DOIs	https://doi.org/10.1007/s12268-012-0146-3
Publication status	Published - 1 Feb 2012
Externally published	Yes

ASJC Scopus subject areas

Biotechnology
Molecular Biology

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10.1007/s12268-012-0146-3

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abstract = "Non-canonical amino acids as building blocks for protein biosynthesis facilitate modifications that go far beyond classical genetic engineering. Two complementary techniques allow either site-specific or residue-specific incorporation. Accordingly, the possible modifications range from atomic changes to the alteration of the overall biophysical characteristics of a protein. In this article, we present the state of the art of this new protein engineering approach.",

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Synthetische Proteine: Protein Engineering mit nicht-kanonischen Aminosäuren

Abstract

ASJC Scopus subject areas

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