Karl Gruber

Univ.-Prof. Mag. Dr.rer.nat.

19982019
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  • 4 Similar Profiles
mandelonitrile lyase Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Cyclization Chemical Compounds
Biosynthesis Chemical Compounds
Oxidoreductases Chemical Compounds
Genes Chemical Compounds
Substrates Chemical Compounds
Crystal structure Chemical Compounds

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Research Output 1998 2019

  • 31 Article
  • 27 Poster
  • 18 (Old data) Lecture or Presentation

A small molecule chaperone rescues the stability and activity of a cancer-associated variant of NAD(P)H:quinone oxidoreductase 1 in vitro

Strandback, E., Lienhart, W-D., Hromic-Jahjefendic, A., Bourgeois, B., Högler, A., Waltenstorfer, D., Winkler, A., Zangger, K., Madl, T., Gruber, K. & Macheroux, P., 30 Oct 2019, In : FEBS letters.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Molecular Chaperones
NAD
Oxidoreductases
Enzyme Stability
Flavin-Adenine Dinucleotide

Evolving the Promiscuity of Elizabethkingia meningoseptica Oleate Hydratase for the Regio- and Stereoselective Hydration of Oleic Acid Derivatives

Engleder, M., Strohmeier, G. A., Weber, H., Steinkellner, G., Leitner, E., Müller, M., Mink, D., Schürmann, M., Gruber, K. & Pichler, H., 27 May 2019, In : Angewandte Chemie - International Edition. 58, 22, p. 7480-7484 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Hydro-Lyases
Oleic acid
Oleic Acid
Fatty acids
Hydration

Oxidative cyclization of N-methyl-dopa by a fungal flavoenzyme of the amine oxidase family

Lahham, M., Pavkov-Keller, T., Fuchs, M., Niederhauser, J., Chalhoub, G., Daniel, B., Kroutil, W., Gruber, K. & Macheroux, P., 1 Jan 2018, In : Journal of Biological Chemistry. 293, 44, p. 17021-17032 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Dihydroxyphenylalanine
Cyclization
Amines
Oxidoreductases
Stereoisomerism

Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

Lanfranchi, E., Pavkov-Keller, T., Koehler, E-M., Diepold, M., Steiner, K., Darnhofer, B., Hartler, J., Van Den Bergh, T., Joosten, H-J., Gruber-Khadjawi, M., Thallinger, G. G., Birner-Gruenberger, R., Gruber, K., Winkler, M. & Glieder, A., 10 May 2017, In : Scientific reports. 7, 46738.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
mandelonitrile lyase
Enzymes
Biocatalysis
Ferns
Crystallography

Erratum: Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

Lanfranchi, E., Pavkov-Keller, T., Koehler, E-M., Diepold, M., Steiner, K., Darnhofer, B., Hartler, J., Bergh, T. V. D., Joosten, H-J., Gruber-Khadjawi, M., Thallinger, G. G., Birner-Gruenberger, R., Gruber, K., Winkler, M. & Glieder, A., 26 May 2017, In : Scientific reports. 7, 46834.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
mandelonitrile lyase
Enzymes

Activities 2017 2017

  • 1 Talk at conference or symposium

Berberine bridge enzyme-like proteins: From characterization to application

Bastian Daniel (Speaker), Barbara Konrad (Contributor), Sabine Pils (Contributor), Julia Messenlehner (Contributor), Marina Toplak (Contributor), Silvia Wallner (Contributor), Karl Gruber (Contributor), Tea Pavkov-Keller (Contributor), Wolfgang Kroutil (Keynote speaker), Michael Fuchs (Contributor), Jörg H Schrittwieser (Contributor), Peter Macheroux (Contributor)
5 Jul 2017

Activity: Talk or presentationTalk at conference or symposiumScience to science