Utilization of optical polarization microscopy in the study of sorption characteristics of wound dressing host materials

Miha Devetak, Zdenka Peršin, Karin Stana Kleinschek, Uroš Maver

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Polarization microscopy was used for evaluation of kinetics of diclofenac sorption in three different wound dressing materials. The sorption kinetics can be evaluated by radii change and intensity of the light traveling through the fiber. The most frequently used host materials for drugs in wound dressings are alginate, polyesters such as polyethylene terephthalate, and viscose. We studied sorption of diclofenac as an example drug. Effective, but rather simple in vitro simulation of diclofenac sorption gives insight into the applicability of the mentioned materials for development of wound healing materials.

Original languageEnglish
Pages (from-to)561-565
Number of pages5
JournalMicroscopy and microanalysis
Volume20
Issue number2
DOIs
Publication statusPublished - 1 Jan 2014
Externally publishedYes

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Keywords

  • alginate
  • diclofenac
  • PET
  • polarization microscopy
  • sorption
  • viscose

ASJC Scopus subject areas

  • Instrumentation

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