Abstract
Flow microreactors utilizing immobilized enzymes are of great interest in biocatalysis development. Most of the common devices are permanently closed, single-use systems, which allow limited physical and chemical surface modifications and evaluation methods. In this paper we will present resealable flowcells that overcome these limitations and moreover allow a quick and easy integration of sensor systems, because of the use of modular building blocks. The devices were utilized to study the enzyme activity of glucose oxidase immobilized on chemically modified glass surfaces under flow conditions, employing integrated optical oxygen sensors for on-line monitoring.
Original language | English |
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Article number | 065012 |
Journal | Journal of Micromechanics and Microengineering |
Volume | 27 |
Issue number | 6 |
DOIs | |
Publication status | Published - 10 May 2017 |
Keywords
- glucose oxidase
- micro(bio)reactor
- modular system
- oxygen sensor
- resealable flowcell
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Mechanics of Materials
- Mechanical Engineering
- Electrical and Electronic Engineering