Synergism of proteomics and mRNA sequencing for enzyme discovery

Lukas Sturmberger, Paal W Wallace, Anton Glieder, Ruth Birner-Gruenberger

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Enzyme catalyzed processes are increasingly complementing chemical manufacturing as new enzymes are being discovered. Although, many industrially applied biocatalysts have been identified by functional screenings technological advances in the omics fields have created a different path to access novelty. Here we describe how omics technologies, especially proteomics and transcriptomics, can complement each other in the aim of finding new enzymatic functions. Special emphasis is laid on how mRNA sequencing Zcan improve proteomic experiments by allowing the generation of high quality protein sequence databases, which subsequently facilitates protein identification.

LanguageEnglish
Pages132-8
Number of pages7
JournalJournal of Biotechnology
Volume235
DOIs
StatusPublished - 10 Oct 2016

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Proteomics
Messenger RNA
Enzymes
Protein Databases
Technology
Proteins

Keywords

  • Journal Article
  • Review

Cite this

Sturmberger, L., Wallace, P. W., Glieder, A., & Birner-Gruenberger, R. (2016). Synergism of proteomics and mRNA sequencing for enzyme discovery. Journal of Biotechnology, 235, 132-8. DOI: 10.1016/j.jbiotec.2015.12.015

Synergism of proteomics and mRNA sequencing for enzyme discovery. / Sturmberger, Lukas; Wallace, Paal W; Glieder, Anton; Birner-Gruenberger, Ruth.

In: Journal of Biotechnology, Vol. 235, 10.10.2016, p. 132-8.

Research output: Contribution to journalArticleResearchpeer-review

Sturmberger, L, Wallace, PW, Glieder, A & Birner-Gruenberger, R 2016, 'Synergism of proteomics and mRNA sequencing for enzyme discovery' Journal of Biotechnology, vol. 235, pp. 132-8. DOI: 10.1016/j.jbiotec.2015.12.015
Sturmberger L, Wallace PW, Glieder A, Birner-Gruenberger R. Synergism of proteomics and mRNA sequencing for enzyme discovery. Journal of Biotechnology. 2016 Oct 10;235:132-8. Available from, DOI: 10.1016/j.jbiotec.2015.12.015
Sturmberger, Lukas ; Wallace, Paal W ; Glieder, Anton ; Birner-Gruenberger, Ruth. / Synergism of proteomics and mRNA sequencing for enzyme discovery. In: Journal of Biotechnology. 2016 ; Vol. 235. pp. 132-8
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