Structural and kinetic evidence that the catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates

Sigrid Egger, Apirat Chaikuad, Mario Klimacek, Kathryn L. Kavanagh, Udo Oppermann, Bernd Nidetzky

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)2119-2129
JournalThe Journal of Biological Chemistry
Volume287
DOIs
Publication statusPublished - 2012

Fields of Expertise

  • Human- & Biotechnology

Treatment code (Nähere Zuordnung)

  • Basic - Fundamental (Grundlagenforschung)

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