Structural and kinetic evidence that the catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates

Sigrid Egger, Apirat Chaikuad, Mario Klimacek, Kathryn L. Kavanagh, Udo Oppermann, Bernd Nidetzky

Research output: Contribution to journalArticleResearchpeer-review

LanguageEnglish
Pages2119-2129
JournalThe Journal of Biological Chemistry
Volume287
DOIs
StatusPublished - 2012

Fields of Expertise

  • Human- & Biotechnology

Treatment code (Nähere Zuordnung)

  • Basic - Fundamental (Grundlagenforschung)

Cite this

Structural and kinetic evidence that the catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates. / Egger, Sigrid; Chaikuad, Apirat; Klimacek, Mario; Kavanagh, Kathryn L.; Oppermann, Udo; Nidetzky, Bernd.

In: The Journal of Biological Chemistry, Vol. 287, 2012, p. 2119-2129.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Kavanagh,Kathryn L.

AU - Oppermann,Udo

AU - Nidetzky,Bernd

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T2 - The Journal of Biological Chemistry

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