Poliuretani za medicinsko uporabo

Translated title of the contribution: Polyurethanes for medical use

Tanja Pivec, Majda Sfiligoj Smole*, Petra Gašparič, Karin Stana Kleinschek

*Corresponding author for this work

Research output: Contribution to specialist publicationArticle

Abstract

Polyurethanes are synthetic copolymers containing urethane linkages in their complex chemical structure. They consist of three monomers: a diisocyanate, a polyol and a chain extender, which enables the synthesis of an endless number of polyurethanes with different physicochemical and mechanical properties. The physicochemical properties of various polyurethanes are largely dependent on the conformation of polyols, which may contain two or more different polyols, stabilisers, catalysts, liquids or solid additives and, in the case of foams, foaming agents. Depending on the structure of the polyols, i.e. the length of the chain, structure of the units (aliphatic or aromatic), ester or ether groups, or functionalisation by hydroxyl groups, polyurethanes may be flexible or rigid, and therefore suitable for various applications. In addition to the physical and chemical structure of polyurethanes, this review paper specifically addresses their use in medicine, particularly in wound dressings, tissue engineering scaffolds and drug delivery with nanoparticles and nanocapsules, and provides guidelines for the development of new biodegradable polyurethane materials.

Original languageSlovenian
Pages182-197
Number of pages16
Volume60
No.3
Specialist publicationTekstilec
DOIs
Publication statusPublished - 1 Jan 2017
Externally publishedYes

Keywords

  • Chemical structure
  • Medical applications
  • Reactants
  • Segmented polyurethanes

ASJC Scopus subject areas

  • Business and International Management
  • Business, Management and Accounting(all)
  • Polymers and Plastics
  • Industrial and Manufacturing Engineering

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