Abstract
The aim of the present study was to prepare a polysaccharide (cellulose ac-
etate) based nanofibrous sensor for detection of pH change in the wound
environment. In order to prepare cellulose acetate (CA) nanofi bers, acetic
acid was used as a solvent, and fabrication of fi bers was performed on the
needle-less electrospinning apparatus. Long uniform CA nanofibers, with
diameters ranging from 250 to 300 nm, were electrospun from 15 wt% CA
and 85% acetic acid, with addition of halochromic dye (Bromocrezol Green).
The addition of Bromocrezol Green in the spinning formulation did not affect
the fi ber formation. Prepared nanofi brous sensors were characterized using
CIE color space analysis in order to evaluate the color due to pH change.
Nanofi brous sensors exhibit yellow color when exposed to pH4 and lower,
simulating the wound environment beneficial to the wound healing, and blue
color when exposed to pH 9 and higher, simulating the environment that
hampers wound healing (chronic, infected wounds)
etate) based nanofibrous sensor for detection of pH change in the wound
environment. In order to prepare cellulose acetate (CA) nanofi bers, acetic
acid was used as a solvent, and fabrication of fi bers was performed on the
needle-less electrospinning apparatus. Long uniform CA nanofibers, with
diameters ranging from 250 to 300 nm, were electrospun from 15 wt% CA
and 85% acetic acid, with addition of halochromic dye (Bromocrezol Green).
The addition of Bromocrezol Green in the spinning formulation did not affect
the fi ber formation. Prepared nanofi brous sensors were characterized using
CIE color space analysis in order to evaluate the color due to pH change.
Nanofi brous sensors exhibit yellow color when exposed to pH4 and lower,
simulating the wound environment beneficial to the wound healing, and blue
color when exposed to pH 9 and higher, simulating the environment that
hampers wound healing (chronic, infected wounds)
| Translated title of the contribution | Polysaccharide based nanofibers with pH-sensitive function |
|---|---|
| Original language | Croatian |
| Pages (from-to) | 166-170 |
| Journal | Tekstil |
| Volume | 65 |
| Issue number | 5/6 |
| Publication status | Published - Jun 2016 |
| Externally published | Yes |