Abstract
A short survey on selected β-galactosidase inhibitors as potential pharmacological chaperones for GM1-gangliosidosis and Morquio B associated mutants of human lysosomal β-galactosidase is provided highlighting recent developments in this particular area of lysosomal storage disorders and orphan diseases
Original language | English |
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Pages (from-to) | 2980-2989 |
Number of pages | 10 |
Journal | The Chemical Record |
Volume | 21 |
Issue number | 11 |
DOIs | |
Publication status | Published - Nov 2021 |
Keywords
- Carbohydrates
- Inhibitors
- Lysosomal storage disease
- Lysosomal β-Galactosidase
- Pharmacological chaperone
ASJC Scopus subject areas
- Materials Chemistry
- General Chemical Engineering
- General Chemistry
- Biochemistry