Abstract
A method for immobilization of heparin on polymeric material is disclosed, said method comprising selecting a substrate made from a polymeric material, pre-treating said substrate, mounting said substrate into a vacuum chamber, evacuating the vacuum chamber to pressure essentially below 100 Pa, preferably below 1 Pa, selecting a source of NH2 radicals, leaking the NH2 radicals from said source into said vacuum chamber during continuous pumping of said vacuum chamber, interacting said NH2 (NH 2 ) radicals with said substrate made from a polymeric material, evacuating said vacuum chamber, venting said vacuum chamber to atmospheric pressure, and covalent bonding of activated heparin on said substrate.
| Translated title of the contribution | VERFAHREN ZUR IMMOBILISIERUNG EINES POLYMERMATERIALS |
|---|---|
| Original language | English |
| Patent number | EP2997984 |
| IPC | A61L 33/ 00 A I |
| Priority date | 19/09/14 |
| Publication status | Published - 23 Mar 2016 |
| Externally published | Yes |
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Cite this
Modic, M., Kolar, M., Stana Kleinschek, K., Mozetic, M., Junkar, I., Vesel, A., ... Vesel, A. (2016). IPC No. A61L 33/ 00 A I. Method for immobilization of heparin on a polymeric material. (Patent No. EP2997984).