Method for immobilization of heparin on a polymeric material

Martina Modic (Inventor), Metod Kolar (Inventor), Karin Stana Kleinschek (Inventor), Miran Mozetic (Inventor), Ita Junkar (Inventor), Alenka Vesel (Inventor), Martina Modic (Inventor), Metod Kolar (Inventor), Miran Mozetic (Inventor), Ita Junkar (Inventor), Alenka Vesel (Inventor)

Research output: PatentResearch

Abstract

A method for immobilization of heparin on polymeric material is disclosed, said method comprising selecting a substrate made from a polymeric material, pre-treating said substrate, mounting said substrate into a vacuum chamber, evacuating the vacuum chamber to pressure essentially below 100 Pa, preferably below 1 Pa, selecting a source of NH2 radicals, leaking the NH2 radicals from said source into said vacuum chamber during continuous pumping of said vacuum chamber, interacting said NH2 (NH 2 ) radicals with said substrate made from a polymeric material, evacuating said vacuum chamber, venting said vacuum chamber to atmospheric pressure, and covalent bonding of activated heparin on said substrate.

Translated title of the contributionVERFAHREN ZUR IMMOBILISIERUNG EINES POLYMERMATERIALS
Original languageEnglish
Patent numberEP2997984
IPCA61L 33/ 00 A I
Priority date19/09/14
Publication statusPublished - 23 Mar 2016
Externally publishedYes

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  • Cite this

    Modic, M., Kolar, M., Stana Kleinschek, K., Mozetic, M., Junkar, I., Vesel, A., ... Vesel, A. (2016). IPC No. A61L 33/ 00 A I. Method for immobilization of heparin on a polymeric material. (Patent No. EP2997984).