In situ synchrotron Х-ray diffraction study of heat-induced structural changes in TiOy/HAp nanocomposites

S. V. Rempel*, D. Eselevich, Z. S. Vinokurov, H. Schroettner, A. A. Rempel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


In situ synchrotron Х-ray diffraction (XRD) was used to study the interactions between an important biomaterial for tissue engineering and regenerative medicine, hydroxyapatite, and titanium monoxide additives of different stoichiometry, in nanocomposite materials. The study was carried out in the temperature range from ambient to 900 °C in a flow of dry air. During the temperature evolution of the nanocomposites, the mutual influences of the matrix and additives were observed. The dynamics of changes in the phase composition and the effects of TiOy on the thermal stability of the matrix were considered. The addition of 10 wt% TiOy increased the decomposition temperature of HAp by approximately 100 °C. Different additive stoichiometries shifted the temperature ranges of the phase transitions in the nanocomposites. Opposite trends were observed for the dependence of the weight content of the matrix and that of the additive on temperature in the range from 300 to 800 °C. This behaviour was explained by a partial substitution of Ti atoms for Ca atoms. After heat treatment to 900 °C, all nanocomposite phases were biocompatible. The oxyapatite and TiO2 phases retained the nanostates of their initial components, while the α- and β-ТСР phases were microcrystalline. In situ synchrotron XRD method proved to be a highly informative and precise technique for studying new biomaterials.

Original languageEnglish
Pages (from-to)2843-2852
Number of pages10
JournalCeramics International
Issue number2
Publication statusPublished - 15 Jan 2022


  • Biomedical applications
  • Hydroxyapatite
  • In-situ synchrotron XRD
  • Nanocomposite

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Process Chemistry and Technology
  • Surfaces, Coatings and Films
  • Materials Chemistry


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