Human Enzymes for Organic Synthesis

Research output: Contribution to journalReview articleResearchpeer-review

Abstract

Human enzymes have been widely studied in various disciplines. The number of reactions taking place in the human body is vast, and so is the number of potential catalysts for synthesis. Herein, we focus on the application of human enzymes that catalyze chemical reactions in course of the metabolism of drugs and xenobiotics. Some of these reactions have been explored on the preparative scale. The major field of application of human enzymes is currently drug development, where they are applied for the synthesis of drug metabolites.

Original languageEnglish
Pages (from-to)13406-13423
Number of pages18
JournalAngewandte Chemie / International Edition
Volume57
Issue number41
DOIs
Publication statusPublished - 2018

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Enzymes
Pharmaceutical Preparations
Xenobiotics
Metabolites
Metabolism
Chemical reactions
Catalysts

Fields of Expertise

  • Human- & Biotechnology

Cite this

Human Enzymes for Organic Synthesis. / Winkler, Margit; Geier, Martina; Hanlon, Steven P; Nidetzky, Bernd; Glieder, Anton.

In: Angewandte Chemie / International Edition , Vol. 57, No. 41, 2018, p. 13406-13423.

Research output: Contribution to journalReview articleResearchpeer-review

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