Fluid volume changes and LBNP response after simulated weightlessness with varied oral sodium supply

H. Hinghofer-Szalkay, A. Rössler, H. Scharfetter, K. Pilz, Z. László

Research output: Contribution to journalConference articleResearchpeer-review

Abstract

There is evidence on body fluid volume effects of head-down tilt bed rest [1] and altered oral sodium supply [2,3], but the combined impact of both has not been investigated in detail. We therefore studied circulatory adaptation to 8 days -6° head down bed rest (HDBR) with different levels (≈140 to ≈430 mM/d) of oral sodium load (SL). We expected decreased extracellular volume and increased aldosterone and PRA levels with low sodium load, and hypothesized that these effects get exaggerated with additional HDBR, also influencing lower body suction (LBNP) responses. Variations in sodium status seem to influence plasma but not interstitial volume, confirming recent results of another group who used different experimental conditions [3].

Original languageEnglish
Pages (from-to)205-206
Number of pages2
JournalEuropean Space Agency, (Special Publication) ESA SP
Issue number501
Publication statusPublished - 1 Sep 2002
EventProceedings of the European Symposium on Life in Space for Life on Earth - Stockholm, Sweden
Duration: 2 Jun 20027 Jun 2002

Fingerprint

Weightlessness
weightlessness
bed rest
volume change
Sodium
sodium
Fluids
fluid
fluids
head down tilt
aldosterone
body fluid
body fluids
Body fluids
suction
tilt
interstitials
Plasmas
plasma
effect

ASJC Scopus subject areas

  • Aerospace Engineering
  • Space and Planetary Science

Cite this

Fluid volume changes and LBNP response after simulated weightlessness with varied oral sodium supply. / Hinghofer-Szalkay, H.; Rössler, A.; Scharfetter, H.; Pilz, K.; László, Z.

In: European Space Agency, (Special Publication) ESA SP, No. 501, 01.09.2002, p. 205-206.

Research output: Contribution to journalConference articleResearchpeer-review

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AU - László, Z.

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