Detection of Motor Endplates in Deep and Pennate Skeletal Muscles in-vivo using Ultrafast Ultrasound

Christoph Leitner; Sergei Vostrikov; Harald Penasso; Pascal A.  Hager; Andrea Cossettini; Luca Benini; Christian Baumgartner

doi:10.1109/IUS46767.2020.9251756

Detection of Motor Endplates in Deep and Pennate Skeletal Muscles in-vivo using Ultrafast Ultrasound

Christoph Leitner^*, Sergei Vostrikov, Harald Penasso, Pascal A. Hager, Andrea Cossettini, Luca Benini, Christian Baumgartner

^*Corresponding author for this work

Institute of Health Care Engineering with European Testing Center of Medical Devices (7180)

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review

Abstract

Until now direct localization of motor endplates for any arbitrary muscle structure was reserved to cadaver studies or restricted to specific muscles in-vivo. Utilizing ultrafast ultrasound we report a versatile in-vivo method for
the detection of motor endplate zones. To achieve this goal, we employ a research ultrasound system with a linear array transducer probe to record ultrasound images of electricallystimulated medial gastrocnemius muscles. An optical flow speckle tracking algorithm is used to track the points along a single
fascicle. We localize motor endplates at intersection points where mechanical contraction waves diverge bidirectionally towards the fiber ends. Contrary to common experimental methods, our proposed ultrafast ultrasound-based approach allows to localize motor endplates also in deep and pennate muscles in-vivo. These results open up new applications for ultrasound in neuromuscular
research.

Original language	English
Title of host publication	IUS 2020 - International Ultrasonics Symposium, Proceedings
Place of Publication	Las Vegas, USA
Publisher	IEEE Xplore
ISBN (Electronic)	9781728154480
DOIs	https://doi.org/10.1109/IUS46767.2020.9251756
Publication status	Published - 7 Sept 2020
Event	IEEE International Ultrasonics Symposium 2020 - Las Vegas, United States Duration: 6 Sept 2020 → 11 Sept 2020

Publication series

Name	IEEE International Ultrasonics Symposium, IUS
Volume	2020-September
ISSN (Print)	1948-5719
ISSN (Electronic)	1948-5727

Conference

Conference	IEEE International Ultrasonics Symposium 2020
Abbreviated title	IEEE IUS 2020
Country/Territory	United States
City	Las Vegas
Period	6/09/20 → 11/09/20

Keywords

High frame rate
In-vivo
Motor endplate band
Motor neuron
Muscle contraction
Muscle fascicle
Pennate muscle
Ultrasonic

ASJC Scopus subject areas

Acoustics and Ultrasonics

Fields of Expertise

Human- & Biotechnology

Access to Document

10.1109/IUS46767.2020.9251756

Cite this

Leitner, C., Vostrikov, S., Penasso, H., Hager, P. A., Cossettini, A., Benini, L., & Baumgartner, C. (2020). Detection of Motor Endplates in Deep and Pennate Skeletal Muscles in-vivo using Ultrafast Ultrasound. In IUS 2020 - International Ultrasonics Symposium, Proceedings Article 9251756 (IEEE International Ultrasonics Symposium, IUS; Vol. 2020-September). IEEE Xplore. https://doi.org/10.1109/IUS46767.2020.9251756

Detection of Motor Endplates in Deep and Pennate Skeletal Muscles in-vivo using Ultrafast Ultrasound. / Leitner, Christoph; Vostrikov, Sergei; Penasso, Harald et al.
IUS 2020 - International Ultrasonics Symposium, Proceedings. Las Vegas, USA: IEEE Xplore, 2020. 9251756 (IEEE International Ultrasonics Symposium, IUS; Vol. 2020-September).

Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review

Leitner, C, Vostrikov, S, Penasso, H, Hager, PA, Cossettini, A, Benini, L & Baumgartner, C 2020, Detection of Motor Endplates in Deep and Pennate Skeletal Muscles in-vivo using Ultrafast Ultrasound. in IUS 2020 - International Ultrasonics Symposium, Proceedings., 9251756, IEEE International Ultrasonics Symposium, IUS, vol. 2020-September, IEEE Xplore, Las Vegas, USA, IEEE International Ultrasonics Symposium 2020, Las Vegas, Nevada, United States, 6/09/20. https://doi.org/10.1109/IUS46767.2020.9251756

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title = "Detection of Motor Endplates in Deep and Pennate Skeletal Muscles in-vivo using Ultrafast Ultrasound",

abstract = "Until now direct localization of motor endplates for any arbitrary muscle structure was reserved to cadaver studies or restricted to specific muscles in-vivo. Utilizing ultrafast ultrasound we report a versatile in-vivo method forthe detection of motor endplate zones. To achieve this goal, we employ a research ultrasound system with a linear array transducer probe to record ultrasound images of electricallystimulated medial gastrocnemius muscles. An optical flow speckle tracking algorithm is used to track the points along a singlefascicle. We localize motor endplates at intersection points where mechanical contraction waves diverge bidirectionally towards the fiber ends. Contrary to common experimental methods, our proposed ultrafast ultrasound-based approach allows to localize motor endplates also in deep and pennate muscles in-vivo. These results open up new applications for ultrasound in neuromuscularresearch.",

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AU - Cossettini, Andrea

AU - Benini, Luca

AU - Baumgartner, Christian

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Detection of Motor Endplates in Deep and Pennate Skeletal Muscles in-vivo using Ultrafast Ultrasound

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

Fields of Expertise

Access to Document

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Cite this