Design of Friction, Morphology, Wetting, and Protein Affinity by Cellulose Blend Thin Film Composition

Caterina Marina Czibula, Gundula Marie Teichert, Maximilian Nau, Mathias Hobisch, Chonnipa Palasingh, Markus Biesalski, Stefan Spirk, Christian Teichert , Tiina Nypelö

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Cellulose derivate phase separation in thin films was applied to generate patterned films with distinct surface morphology. Patterned polymer thin films are utilized in electronics, optics, and biotechnology but films based on bio-polymers are scarce. Film formation, roughness, wetting, and patterning are often investigated when it comes to characterization of the films. Frictional properties, on the other hand, have not been studied extensively. We extend the fundamental understanding of spin coated complex cellulose blend films via revealing their surface friction using Friction Force Microscopy (FFM). Two cellulose derivatives were transformed into two-phase blend films with one phase comprising trimethyl silyl cellulose (TMSC) regenerated to cellulose with hydroxyl groups exposed to the film surface. Adjusting the volume fraction of the spin coating solution resulted in variation of the surface fraction with the other, hydroxypropylcellulose stearate (HPCE) phase. The film morphology confirmed lateral and vertical separation and was translated into effective surface fraction. Phase separation as well as regeneration contributed to the surface morphology resulting in roughness variation of the blend films from 1.1 to 19.8 nm depending on the film composition. Friction analysis was successfully established, and then revealed that the friction coefficient of the films could be tuned and the blend films exhibited lowered friction force coefficient compared to the single-component films. Protein affinity of the films was investigated with bovine serum albumin (BSA) and depended mainly on the surface free energy (SFE) while no direct correlation with roughness or friction was found. BSA adsorption on film formed with 1:1 spinning solution volume ratio was an outlier and exhibited unexpected minimum in adsorption.
Original languageEnglish
Article number239
Number of pages10
JournalFrontiers in Chemistry
Volume7
DOIs
Publication statusPublished - 2019

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Cellulose
Wetting
Friction
Thin films
Chemical analysis
Proteins
Surface roughness
Bovine Serum Albumin
Phase separation
Surface morphology
Cellulose derivatives
Stearates
Adsorption
Spin coating
Biotechnology
Polymer films
Hydroxyl Radical
Free energy
Optics
Volume fraction

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Design of Friction, Morphology, Wetting, and Protein Affinity by Cellulose Blend Thin Film Composition. / Czibula, Caterina Marina; Teichert, Gundula Marie; Nau, Maximilian; Hobisch, Mathias; Palasingh, Chonnipa; Biesalski, Markus; Spirk, Stefan; Teichert , Christian; Nypelö, Tiina.

In: Frontiers in Chemistry, Vol. 7, 239, 2019.

Research output: Contribution to journalArticleResearchpeer-review

Czibula, Caterina Marina ; Teichert, Gundula Marie ; Nau, Maximilian ; Hobisch, Mathias ; Palasingh, Chonnipa ; Biesalski, Markus ; Spirk, Stefan ; Teichert , Christian ; Nypelö, Tiina. / Design of Friction, Morphology, Wetting, and Protein Affinity by Cellulose Blend Thin Film Composition. In: Frontiers in Chemistry. 2019 ; Vol. 7.
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