Defining patient centric pharmaceutical drug product design

Sven Stegemann*, Robert L. Ternik, Graziano Onder, Mansoor A. Khan, Diana A. van Riet-Nales

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The term “patient centered,” “patient centric,” or “patient centricity” is increasingly used in the scientific literature in a wide variety of contexts. Generally, patient centric medicines are recognized as an essential contributor to healthy aging and the overall patient’s quality of life and life expectancy. Besides the selection of the appropriate type of drug substance and strength for a particular indication in a particular patient, due attention must be paid that the pharmaceutical drug product design is also adequately addressing the particular patient’s needs, i.e., assuring adequate patient adherence and the anticipate drug safety and effectiveness. Relevant pharmaceutical design aspects may e.g., involve the selection of the route of administration, the tablet size and shape, the ease of opening the package, the ability to read the user instruction, or the ability to follow the recommended (in-use) storage conditions. Currently, a harmonized definition on patient centric drug development/design has not yet been established. To stimulate scientific research and discussions and the consistent interpretation of test results, it is essential that such a definition is established. We have developed a first draft definition through various rounds of discussions within an interdisciplinary AAPS focus group of experts. This publication summarizes the outcomes and is intended to stimulate further discussions with all stakeholders towards a common definition of patient centric pharmaceutical drug product design that is useable across all disciplines involved.
Original languageEnglish
Pages (from-to)1047-1055
JournalThe AAPS journal
Volume18
Issue number5
DOIs
Publication statusPublished - 1 Apr 2016

Keywords

  • Patient centricity
  • definition

ASJC Scopus subject areas

  • Health Professions(all)

Fields of Expertise

  • Human- & Biotechnology

Treatment code (Nähere Zuordnung)

  • Basic - Fundamental (Grundlagenforschung)

Fingerprint

Dive into the research topics of 'Defining patient centric pharmaceutical drug product design'. Together they form a unique fingerprint.

Cite this