Complete DNA sequence of yeast chromosome XI

Research output: Contribution to journalArticlepeer-review

Abstract

The complete DNA sequence of the yeast Saccharomyces cerevisiae chromosome XI has been determined. In addition to a compact arrangement of potential protein coding sequences, the 666,448-base-pair sequence has revealed general chromosome patterns; in particular, alternating regional variations in average base composition correlate with variations in local gene density along the chromosome. Significant discrepancies with the previously published genetic map demonstrate the need for using independent physical mapping criteria.
Original languageEnglish
Pages (from-to)371-378
JournalNature
Volume369
DOIs
Publication statusPublished - 1994
Externally publishedYes

Fields of Expertise

  • Human- & Biotechnology

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