C-5a-substituted validamine type glycosidase inhibitors.

Michael Schalli, Andreas Wolfsgruber, Andres Gonzalez Santana, Christina Tysoe, Roland Fischer, Arnold Stütz, Martin Thonhofer, Stephen G. Withers

Research output: Contribution to journalArticle


A series of N-alkyl derivs. of the D-galactosidase inhibitor 1,4-di-epi-validamine featuring lipophilic substituents at position C-5a was prepd. and screened for their glycosidase inhibitory properties. Products turned out selective for β-galactosidases as well as β-glucosidases. [on SciFinder(R)]
Original languageEnglish
Pages (from-to)1-9
Number of pages9
JournalCarbohydrate Research
Publication statusPublished - 2017

Cite this