Biologically relevant small radicals

Georg Bauer, C. Chatgilialoglu, J. L. Gebicki, L. Gebicka, Georg Gescheidt-Demner, B. T. Golding, S. Goldstein, J. Kaizer, G. Merenyi, G. Speier, P. Wardman

Research output: Contribution to journalArticle

Abstract

Biologically relevant small radicals are at the focus of the working group 4 (WG4) of the COST Action CM0603 (Free Radicals in Chemical Biology, CHEMBIORADICAL). This article surveys the areas of research being undertaken by the partners in WG4. The character of the radicals is described together with experimental techniques utilized to follow their structure and reactivity. Specifically, C-, S-, N- and O-centered radicals of small size, and their interaction with different biomolecules are described. Processes at the molecular level exemplifying important biological signaling and damaging pathways are introduced.
Original languageEnglish
Pages (from-to)704-712
JournalChimia
Volume62
Publication statusPublished - 2008

Treatment code (Nähere Zuordnung)

  • Experimental

Cite this