@article{4117646cc6da4133af543106516da014,
title = "Accelerated Reaction Engineering of Photo(bio)catalytic Reactions through Parallelization with an Open-Source Photoreactor",
abstract = "Photobiocatalysis is an alternative approach in synthesis that has received much attention in the recent years. Due to the youth of the topic, only few reactor systems are commercially available. To allow a parallel parameter-screening approach as often used in the optimization of biocatalytic processes, a photoreactor was developed that can illuminate up to 24 samples at well-defined reaction conditions. The device{\textquoteleft}s optical features and temperature regulation have been thoroughly characterized and its application was demonstrated in four examples, specifically three photobiocatalytic and one photocatalytic process: (i) Light-dependent decarboxylation using a photodecarboxylase; (ii) Reduction of protochlorophyllide using a protochlorophyllide oxidoreductase; (iii) Photosynthetic oxygen production performed by cyanobacteria; and (iv) (−)-Riboflavin-catalyzed (E/Z)-isomerization of cinnamic acid derivatives.",
keywords = "open source, photobiocatalysis, photocatalysis, photoenzymes, photoreactors, reaction engineering",
author = "Winkler, {Christoph K.} and Stefan Simi{\'c} and Valentina Jurka{\v s} and Sarah Bierbaumer and Luca Schmermund and Silvan Poschenrieder and Berger, {Sarah A.} and Elisa Kulterer and Robert Kourist and Wolfgang Kroutil",
note = "Funding Information: This work has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement No. 862081 (CLASSY) and under the Marie Sk?odowska-Curie grant agreement No. 764920 (PhotoBioCat). S.B. acknowledges the Austrian Science Fund (FWF) for funding within the project CATALOX (DOC 46-B21). We thank Prof. Robert Kourist, Graz University of Technology, for providing the strain Synechocystis sp. PCC 6083. The University of Graz and the Field of Excellence BioHealth are acknowledged for financial support. Funding Information: This work has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement No. 862081 (CLASSY) and under the Marie Sk{\l}odowska‐Curie grant agreement No. 764920 (PhotoBioCat). S.B. acknowledges the Austrian Science Fund (FWF) for funding within the project CATALOX (DOC 46‐B21). We thank Prof. Robert Kourist, Graz University of Technology, for providing the strain Synechocystis sp. PCC 6083. The University of Graz and the Field of Excellence BioHealth are acknowledged for financial support. Publisher Copyright: {\textcopyright} 2021 The Authors. ChemPhotoChem published by Wiley-VCH GmbH",
year = "2021",
month = oct,
doi = "10.1002/cptc.202100109",
language = "English",
volume = "5",
pages = "957--965",
journal = "ChemPhotoChem",
issn = "2367-0932",
publisher = "Wiley-VCH ",
number = "10",
}