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  • Martina Geier
2020

Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications

Wiltschi, B., Cernava, T., Dennig, A., Galindo, M., Geier, M., Gruber, S., Haberbauer, M., Heidinger, P., Acero, E. H., Kratzer, R., Luley-Goedl, C., Müller, C. A., Pitzer, J., Ribitsch, D., Sauer, M., Schmölzer, K., Schnitzhofer, W., Sensen, C. W., Soh, J., Steiner, K. & 3 others, Winkler, C. K., Winkler, M. & Wriessnegger, T., 22 Jan 2020, In : Biotechnology Advances. p. 107520

Research output: Contribution to journalArticle

2016

A Toolbox of Diverse Promoters Related to Methanol Utilization: Functionally Verified Parts for Heterologous Pathway Expression in Pichia pastoris

Vogl, T., Sturmberger, L., Kickenweiz, T., Wasmayer, R., Schmid, C., Hatzl, A-M., Gerstmann, M. A., Pitzer, J., Wagner, M., Thallinger, G. G., Geier, M. & Glieder, A., 19 Feb 2016, In : ACS Synthetic Biology . 5, 2, p. 172-86 15 p.

Research output: Contribution to journalArticle

Biocatalytic Characterization of Human FMO5: Unearthing Baeyer-Villiger Reactions in Humans

Fiorentini, F., Geier, M., Binda, C., Winkler, M., Faber, K., Hall, M. & Matteiv, A., 2016, In : ACS Chemical Biology. p. 1039 1048 p.

Research output: Contribution to journalArticle

COMPACT AND OPTIMIZED METABOLIC PATHWAY DESIGN IN PICHIA PASTORIS

Geier, M., Glieder, A. & Fauland, P., 6 May 2016, IPC No. C12N 15/ 09 A I, Patent No. WO2016066711, Priority date 28 Oct 2014, Priority No. EP20140190702

Research output: Patent

Refined Pichia pastoris reference genome sequence

Sturmberger, L., Chappell, T., Geier, M., Krainer, F., Day, K. J., Vide, U., Trstenjak, S., Schiefer, A., Richardson, T., Soriaga, L., Darnhofer, B., Birner-Gruenberger, R., Glick, B. S., Tolstorukov, I., Cregg, J., Madden, K. & Glieder, A., 10 Oct 2016, In : Journal of Biotechnology. 235, p. 121-131 11 p.

Research output: Contribution to journalReview article

2015

Biotransformations for drug metabolite synthesis

Winkler, M., Bachler, T., Geier, M., Hanlon, S. P., Eggimann, F. K., Rodrigues, D., Ferreira Antunes, M., Kittelmann, M., Glieder, A., Wirz, B. & Lütz, S., 2015.

Research output: Contribution to conferencePoster

Compact multi-enzyme pathways in P. pastoris

Geier, M., Fauland, P. C., Vogl, T. & Glieder, A., 2015, In : Chemical Communications. 15, 51;9, p. 1643-1646

Research output: Contribution to journalArticle

Drug Metabolizing Enzymes: From Heterologous Expression to Drug Metabolite Synthesis

Winkler, M., Bachler, T., Geier, M., Glieder, A., Hanlon, S. P., Eggimann, F. K., Rodrigues, D., Antunes, M., Kittelmann, M., Wirz, B. & Lütz, S., 2015.

Research output: Contribution to conferencePoster

Engineering Pichia pastoris for improved NADH regeneration: A novel chassis strain for whole-cell catalysis

Geier, M., Brandner, C., Strohmeier, G. A., Hall, M., Hartner, F. S. & Glieder, A., 2015, In : Beilstein Journal of Organic Chemistry . 11, p. 1741-8 8 p.

Research output: Contribution to journalArticle

Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis

Geier, M., Bachler, T., Hanlon, S. P., Eggimann, F. K., Kittelmann, M., Weber, H., Lütz, S., Wirz, B. & Winkler, M., 2015, In : Microbial cell factories . 14, 82, p. 1-10

Research output: Contribution to journalArticle

2014

Generating a Platform of Human Non-CYP Drug Metabolizing Enzymes for API Modification

Geier, M., Bachler, T., Eggimann, F., Rodrigues, D., Hanlon, S., Wirz, B., Kittelmann, M., Lütz, S., Glieder, A. & Winkler, M., 2014.

Research output: Contribution to conferencePoster

Human flavin monooxygenase 2: Heterologous expression in E. coli and API modification

Winkler, M., Geier, M., Bachler, T., Hanlon, S., Kittelmann, M., Glieder, A., Lütz, S. & Wirz, B., 2014.

Research output: Contribution to conferencePoster

Human flavin monooxygenase 2: Heterologous expression in E. coli and API modification

Winkler, M., Geier, M., Bachler, T., Hanlon, S. P., Kittelmann, M., Glieder, A., Lütz, S. & Wirz, B., 2014, New Biotechnology. ., p. S82-S82

Research output: Chapter in Book/Report/Conference proceedingConference contribution

New tools for pathway generation employing the concepts of synthetic biology

Geier, M., Vogl, T., Sturmberger, L., Schmid, C., Wiltschi, B. & Glieder, A., 2014.

Research output: Contribution to conferencePoster

Preliminary characterization of hFMO5. A human Bayer-Villiger Monooxygenase?

Fiorentini, F., Hall, M., Winkler, M., Geier, M., Binda, C., Faber, K. & Mattevi, A., 2014.

Research output: Contribution to conferencePoster

2013

ACIB and CHEM21: Towards greener and more sustainable pharmaceutical manufacturing processes

Geier, M., Killinger, M., Wiltschi, B., Gruber-Khadjawi, M., Lypetska, K., Strohmeier, G., Breinbauer, R., Turrini, N., Faber, K. & Glieder, A., 2013.

Research output: Contribution to conferencePoster

Double site saturation mutagenesis of the human cytochrome P450 2D6 results in regioselective steroid hydroxylation

Geier, M., Braun, A., Fladischer, P., Stepniak, P., Rudroff, F., Hametner, C., Mihovilovic, M. & Glieder, A., 2013, In : The FEBS journal. 280, 13, p. 3094-108

Research output: Contribution to journalArticle

First functional expression of cytochrome P450 3A4 in Pichia pastoris

Geier, M., Schmid, C. & Glieder, A., 2013, In : Chimica Oggi. 31, 3, p. 24-27

Research output: Contribution to journalArticle

Human Flavin Monooxygenases as a Tool for Drug Metabolite Synthesis

Bachler, T., Hanlon, S. P., Kittelmann, M., Geier, M., Camattari, A., Glieder, A., Wirz, B., Lütz, S. & Winkler, M., 2013.

Research output: Contribution to conferencePoster

Protein Engineering Using Eukaryotic Expression Systems

Geier, M. & Glieder, A., 2013, Protein Engineering Handbook - Volume 3. Weinheim, Germany: Wiley-VCH , p. 47-72

Research output: Chapter in Book/Report/Conference proceedingChapter

Towards drug metabolite production on the multi-miligram scale: Generation of an efficient aldehyde oxidase (AOX1) based biocatalyst

Bachler, T., Rodrigues, D. F., Kittelmann, M., Geier, M., Abad, S., Hanlon, S. P., Camattari, A., Lütz, S., Wirz, B. & Winkler, M., 2013.

Research output: Contribution to conferencePoster

2012

MuteinDB: the mutein database linking substrates, products and enzymatic reactions directly with genetic variants of enzymes

Braun, A., Halwachs, B., Geier, M., Weinhandl, K., Guggemos, M., Marienhagen, J., Ruff, A. J., Schwaneberg, U., Torres Pazmiño, D. E., Rabin, V., Thallinger, G. & Glieder, A., 2012, In : Database - The Journal of Biological Databases and Curation . p. bas028-bas028

Research output: Contribution to journalArticle

Steroid biotransformations in biphasic systems with Yarrowia lipolytica expressing human liver cytochrome P450 genes

Braun, A., Geier, M., Buehler, B., Schmid, A., Mauersberger, S. & Glieder, A., 2012, In : Microbial cell factories . 11, p. 106

Research output: Contribution to journalArticle