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  • Leila Taher
Article

A Dispensable Chromosome Is Required for Virulence in the Hemibiotrophic Plant Pathogen Colletotrichum higginsianum

Plaumann, P-L., Schmidpeter, J., Dahl, M., Taher, L. & Koch, C., 2018, In : Frontiers in Microbiology . 9, p. 1005

Research output: Contribution to journalArticleResearchpeer-review

A high-resolution enhancer atlas of the developing telencephalon

Visel, A., Taher, L., Girgis, H., May, D., Golonzhka, O., Hoch, R. V., McKinsey, G. L., Pattabiraman, K., Silberberg, S. N., Blow, M. J., Hansen, D. V., Nord, A. S., Akiyama, J. A., Holt, A., Hosseini, R., Phouanenavong, S., Plajzer-Frick, I., Shoukry, M., Afzal, V., Kaplan, T. & 5 othersKriegstein, A. R., Rubin, E. M., Ovcharenko, I., Pennacchio, L. A. & Rubenstein, J. L. R., 14 Feb 2013, In : Cell. 152, 4, p. 895-908 14 p.

Research output: Contribution to journalArticleResearchpeer-review

A machine learning approach for identifying novel cell type-specific transcriptional regulators of myogenesis

Busser, B. W., Taher, L., Kim, Y., Tansey, T., Bloom, M. J., Ovcharenko, I. & Michelson, A. M., 2012, In : PLoS Genetics. 8, 3, p. e1002531

Research output: Contribution to journalArticleResearchpeer-review

Analysis of microRNA and Gene Expression Profiles in Multiple Sclerosis: Integrating Interaction Data to Uncover Regulatory Mechanisms

Freiesleben, S., Hecker, M., Zettl, U. K., Fuellen, G. & Taher, L., 3 Oct 2016, In : Scientific Reports. 6, p. 34512

Research output: Contribution to journalArticleResearchpeer-review

An integrated genome-wide multi-omics analysis of gene expression dynamics in the preimplantation mouse embryo

Israel, S., Ernst, M., Psathaki, O. E., Drexler, H. C. A., Casser, E., Suzuki, Y., Makalowski, W., Boiani, M., Fuellen, G. & Taher, L., 16 Sep 2019, In : Scientific Reports. 9, 1, p. 13356

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Bioinformatics approaches to single-blastomere transcriptomics

Taher, L., Pfeiffer, M. J. & Fuellen, G., Feb 2015, In : Molecular Human Reproduction. 21, 2, p. 115-25 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Cancer Is Associated with Alterations in the Three-Dimensional Organization of the Genome

Li, L., Barth, N. K. H., Pilarsky, C. & Taher, L., 27 Nov 2019, In : Cancers. 11, 12

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness

Furusawa, T., Rochman, M., Taher, L., Dimitriadis, E. K., Nagashima, K., Anderson, S. & Bustin, M., 22 Jan 2015, In : Nature Communications. 6, p. 6138

Research output: Contribution to journalArticleResearchpeer-review

CLARE: Cracking the LAnguage of Regulatory Elements

Taher, L., Narlikar, L. & Ovcharenko, I., 15 Feb 2012, In : Bioinformatics. 28, 4, p. 581-3 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Comparative computational analysis of pluripotency in human and mouse stem cells

Ernst, M., Abu Dawud, R., Kurtz, A., Schotta, G., Taher, L. & Fuellen, G., 21 Jan 2015, In : Scientific Reports. 5, p. 7927

Research output: Contribution to journalArticleResearchpeer-review

Comparative High-Resolution Transcriptome Sequencing of Lymphoma Cell Lines and de novo Lymphomas Reveals Cell-Line-Specific Pathway Dysregulation

Taher, L., Beck, J., Liu, W., Roolf, C., Soller, J. T., Rütgen, B. C., Hammer, S. E., Chodisetti, M., Sender, S., Sterenczak, K. A., Fuellen, G., Junghanss, C., Brenig, B., Nolte, I., Schütz, E. & Murua Escobar, H., 19 Apr 2018, In : Scientific Reports. 8, 1, p. 6279

Research output: Contribution to journalArticleResearchpeer-review

CRISPR/Cas9-Mediated Knock-Out of KrasG12D Mutated Pancreatic Cancer Cell Lines

Lentsch, E., Li, L., Pfeffer, S., Ekici, A. B., Taher, L., Pilarsky, C. & Grützmann, R., 14 Nov 2019, In : International Journal of Molecular Sciences . 20, 22, 11 p., 5706.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Differences in embryo quality are associated with differences in oocyte composition: a proteomic study in inbred mice

Pfeiffer, M. J., Taher, L., Drexler, H., Suzuki, Y., Makałowski, W., Schwarzer, C., Wang, B., Fuellen, G. & Boiani, M., Feb 2015, In : Proteomics. 15, 4, p. 675-87 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Effects of HMGN variants on the cellular transcription profile

Rochman, M., Taher, L., Kurahashi, T., Cherukuri, S., Uversky, V. N., Landsman, D., Ovcharenko, I. & Bustin, M., May 2011, In : Nucleic acids research. 39, 10, p. 4076-87 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Evolutionary conserved networks of human height identify multiple Mendelian causes of short stature

Hauer, N. N., Popp, B., Taher, L., Vogl, C., Dhandapany, P. S., Büttner, C., Uebe, S., Sticht, H., Ferrazzi, F., Ekici, A. B., De Luca, A., Klinger, P., Kraus, C., Zweier, C., Wiesener, A., Jamra, R. A., Kunstmann, E., Rauch, A., Wieczorek, D., Jung, A-M. & 5 othersRohrer, T. R., Zenker, M., Doerr, H-G., Reis, A. & Thiel, C. T., Jul 2019, In : European Journal of Human Genetics . 27, 7, p. 1061-1071 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes

Martin, D., Pantoja, C., Fernández Miñán, A., Valdes-Quezada, C., Moltó, E., Matesanz, F., Bogdanović, O., de la Calle-Mustienes, E., Domínguez, O., Taher, L., Furlan-Magaril, M., Alcina, A., Cañón, S., Fedetz, M., Blasco, M. A., Pereira, P. S., Ovcharenko, I., Recillas-Targa, F., Montoliu, L., Manzanares, M. & 4 othersGuigó, R., Serrano, M., Casares, F. & Gómez-Skarmeta, J. L., Jun 2011, In : Nature structural & molecular biology. 18, 6, p. 708-14 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Genome-wide identification of conserved regulatory function in diverged sequences

Taher, L., McGaughey, D. M., Maragh, S., Aneas, I., Bessling, S. L., Miller, W., Nobrega, M. A., McCallion, A. S. & Ovcharenko, I., Jul 2011, In : Genome research. 21, 7, p. 1139-49 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Genomic analysis of transcriptional networks directing progression of cell states during MGE development

Sandberg, M., Taher, L., Hu, J., Black, B. L., Nord, A. S. & Rubenstein, J. L. R., 14 Sep 2018, In : Neural networks. 13, 1, p. 21

Research output: Contribution to journalArticleResearchpeer-review

Global gene expression analysis of murine limb development

Taher, L., Collette, N. M., Murugesh, D., Maxwell, E., Ovcharenko, I. & Loots, G. G., 2011, In : PLoS ONE. 6, 12, p. e28358

Research output: Contribution to journalArticleResearchpeer-review

Identification of Prognostic Biomarkers by Combined mRNA and miRNA Expression Microarray Analysis in Pancreatic Cancer

Liu, B., Yang, H., Taher, L., Denz, A., Grützmann, R., Pilarsky, C. & Weber, G. F., Jun 2018, In : Translational Oncology. 11, 3, p. 700-714 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Identifying genes relevant to specific biological conditions in time course microarray experiments

Singh, N. K., Repsilber, D., Liebscher, V., Taher, L. & Fuellen, G., 2013, In : PLoS ONE. 8, 10, p. e76561

Research output: Contribution to journalArticleResearchpeer-review

INDEPENDENT TRANSPOSON EXAPTATION IS A WIDESPREAD MECHANISM OF REDUNDANT ENHANCER EVOLUTION IN THE MAMMALIAN GENOME

Barth, N. K. H., Li, L. & Taher, L., 17 Jan 2020, In : Genome Biology and Evolution. evaa004.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model

Smith, R. P., Taher, L., Patwardhan, R. P., Kim, M. J., Inoue, F., Shendure, J., Ovcharenko, I. & Ahituv, N., Sep 2013, In : Nature genetics. 45, 9, p. 1021-1028 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Pairs of Adjacent Conserved Noncoding Elements Separated by Conserved Genomic Distances Act as Cis-Regulatory Units

Li, L., Barth, N. K. H., Hirth, E. & Taher, L., 1 Sep 2018, In : Genome Biology and Evolution. 10, 9, p. 2535-2550 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Revealing complex function, process and pathway interactions with high-throughput expression and biological annotation data

Singh, N. K., Ernst, M., Liebscher, V., Fuellen, G. & Taher, L., 20 Oct 2016, In : Molecular BioSystems. 12, 10, p. 3196-208 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Sequence signatures extracted from proximal promoters can be used to predict distal enhancers

Taher, L., Smith, R. P., Kim, M. J., Ahituv, N. & Ovcharenko, I., 2013, In : Genome biology. 14, 10, p. R117

Research output: Contribution to journalArticleResearchpeer-review

Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner

Collette, N. M., Yee, C. S., Murugesh, D., Sebastian, A., Taher, L., Gale, N. W., Economides, A. N., Harland, R. M. & Loots, G. G., 1 Nov 2013, In : BMC Biology . 383, 1, p. 90-105 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Subpallial Enhancer Transgenic Lines: a Data and Tool Resource to Study Transcriptional Regulation of GABAergic Cell Fate

Silberberg, S. N., Taher, L., Lindtner, S., Sandberg, M., Nord, A. S., Vogt, D., Mckinsey, G. L., Hoch, R., Pattabiraman, K., Zhang, D., Ferran, J. L., Rajkovic, A., Golonzhka, O., Kim, C., Zeng, H., Puelles, L., Visel, A. & Rubenstein, J. L. R., 5 Oct 2016, In : Neuron. 92, 1, p. 59-74 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Suitability of ultrasound-guided fine-needle aspiration biopsy for transcriptome sequencing of the canine prostate

Thiemeyer, H., Taher, L., Schille, J. T., Harder, L., Hungerbuehler, S. O., Mischke, R., Hewicker-Trautwein, M., Kiełbowicz, Z., Brenig, B., Schütz, E., Beck, J., Murua Escobar, H. & Nolte, I., 1 Dec 2019, In : Scientific Reports. 9, 1, 13216.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Systematic elucidation and in vivo validation of sequences enriched in hindbrain transcriptional control

Burzynski, G. M., Reed, X., Taher, L., Stine, Z. E., Matsui, T., Ovcharenko, I. & McCallion, A. S., Nov 2012, In : Genome research. 22, 11, p. 2278-89 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Transcriptional regulation of enhancers active in protodomains of the developing cerebral cortex

Pattabiraman, K., Golonzhka, O., Lindtner, S., Nord, A. S., Taher, L., Hoch, R., Silberberg, S. N., Zhang, D., Chen, B., Zeng, H., Pennacchio, L. A., Puelles, L., Visel, A. & Rubenstein, J. L. R., 4 Jun 2014, In : Neuron. 82, 5, p. 989-1003 15 p.

Research output: Contribution to journalArticleResearchpeer-review

TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability

Bahnassawy, L., Perumal, T. M., Gonzalez-Cano, L., Hillje, A-L., Taher, L., Makalowski, W., Suzuki, Y., Fuellen, G., del Sol, A. & Schwamborn, J. C., 26 Aug 2015, In : Scientific Reports. 5, p. 13456

Research output: Contribution to journalArticleResearchpeer-review

Review article

Identification and computational analysis of gene regulatory elements

Taher, L., Narlikar, L. & Ovcharenko, I., 5 Jan 2015, In : Cold Spring Harbor Protocols. 2015, 1, p. pdb.top083642

Research output: Contribution to journalReview articleResearchpeer-review