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  • Johannes Khinast
2012

Predictive Modeling of Hot Melt Extruders

Eitzlmayr, A., Treffer, D. F., Hörl, G., Windhab, S., Koscher, G. & Khinast, J., 2012, 2012 AIChE Annual Meeting Conference Proceedings. ., p. 0-0

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2014

Optical coherence tomography data processing for in-line monitoring of a pharmaceutical film-coating process

Markl, D., Hannesschläger, G., Sacher, S., Buchsbaum, A. & Khinast, J., 2014, Proceedings of the 10th Minisymposium Verfahrenstechnik. ., p. 142-145

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2015

Novel palladium substituted cerium-tin-oxides as highly active catalysts for continuous Suzuki-Miyaura reactions

Lichtenegger, G. J., Deshpande, P., Gruber-Wölfler, H. & Khinast, J., 2015.

Research output: Contribution to conferencePoster

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2012

Rational Design of Lipophilic Calcium Stearate Pellets Produced via HME

Jedinger, N., Fuchs, K., Koscher, G., Khinast, J. & Roblegg, E., 2012.

Research output: Contribution to conferencePoster

2011

Industrial PAT Use Cases

Wahl, P., Scheibelhofer, O., Koller, D. M., Straka, G., Reiter, F., Schlingmann, M. & Khinast, J. G., 2011.

Research output: Contribution to conferencePoster

Application of Process Analytical Technology (PAT) in Pharmaceutical Production

Wahl, P., Scheibelhofer, O., Koller, D. M. & Khinast, J., 2011.

Research output: Contribution to conferencePoster

2015

In-line Monitoring of Segregation Effects in a Pharmaceutical Tableting Process

Sacher, S., Wahl, P., Scheibelhofer, O., Hohl, R. & Khinast, J., 25 Jan 2015.

Research output: Contribution to conference(Old data) Lecture or Presentation

2016

The Plug & Play Reactor: A Highly Flexible Device for Heterogeneous Reactions in Continuous Flow

Lichtenegger, G. J., Turšič, V., Kitzler, H., Obermaier, K., Khinast, J. & Gruber-Wölfler, H., 27 Jul 2016, In : Chemie - Ingenieur - Technik. 88, 10

Research output: Contribution to journalArticle

2013

Experimental Characterization and Modeling of Twin-Screw Extruder Elements for Pharmaceutical Hot Melt Extrusion

Eitzlmayr, A., Hörl, G., Koscher, G., Reynolds, G., Huang, Z., Booth, J., Shering, P. & Khinast, J., 2013, In : AIChE Journal. 59, 11, p. 4440-4450

Research output: Contribution to journalArticle

2011
2015

Accuracy of micro powder dosing via a vibratory sieve–chute system

Besenhard, M., Faulhammer, E., Fathollahi, S., Reif, G., Calzolari, V., Biserni, S., Lawrence, S., Llusa, M. & Khinast, J., 2015, In : European journal of pharmaceutics and biopharmaceutics. 94, p. 264-272

Research output: Contribution to journalArticle

2013

Supervisory Control System for Monitoring a Pharmaceutical Hot Melt Extrusion Process

Markl, D., Wahl, P., Menezes, J. C., Koller, D. M., Kavsek, B., Francois, K., Roblegg, E. & Khinast, J., 2013, In : AAPS PharmSciTech . 14, 2, p. 1-11

Research output: Contribution to journalArticle

2014

Fast real-time monitoring of entacapone crystallization and characterization of polymorphs via Raman spectroscopy, statistics and SWAXS

Jednačak, T., Hodzic, A., Scheibelhofer, O., Marijan, M., Khinast, J. & Novak, P., 2014, In : Acta pharmaceutica. 64, 1, p. 1-13

Research output: Contribution to journalArticle

2012

Pharmaceutical Hot-Melt Extrusion and Novel Hot-Die Face Pelletizing

Treffer, D. F., Mürb, R-K., Koscher, G. & Khinast, J., 2012.

Research output: Contribution to conferencePoster

2011

A deeper understanding of tablet coating processes through Discrete Element Method simulations

Toschkoff, G., Suzzi, D. & Khinast, J., 31 Mar 2011.

Research output: Contribution to conference(Old data) Lecture or Presentation

2015

EXTRACTABLES AND LEACHABLES FROM FILTER MATERIAL AND THEIR IMPACT ON PROTEIN FORMULATION

Wahl, V., Wieser, J., Mohr, S., Khinast, J. & Paudel, A., 2015, Programme & Abstracts. Ghent: ., p. 114-115

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Total Surveillance! Inline Monitoring of Tablets via NIR Chemical Imaging

Wahl, P., Scheibelhofer, O., Sacher, S. & Khinast, J., 25 Jan 2015.

Research output: Contribution to conference(Old data) Lecture or Presentation

2016

Ce0.495Sn0.495Pd0.01O2 as highly stable and low-leaching catalyst in continuous Suzuki-Miyaura cross-coupling reactions

Lichtenegger, G. J., Khinast, J. & Gruber-Wölfler, H., 2016.

Research output: Contribution to conference(Old data) Lecture or Presentation

Speed change experiments in a rotary tablet press

Martinetz, M., Aigner, I., Rehrl, J., Sacher, S. & Khinast, J., 3 Oct 2016.

Research output: Contribution to conferencePoster

NANEX: Process design and optimization

Baumgartner, R., Matic, J., Schrank, S., Laske, S., Khinast, J. & Roblegg, E., 14 Apr 2016, In : International Journal of Pharmaceutics. 506, p. 35-45 10 p.

Research output: Contribution to journalArticle

2017

An investigation of the hydrodynamic similarity of single-spout fluidized beds using CFD-DEM simulations

Ebrahimi, M., Siegmann, E., Prieling, D., Glasser, B. J. & Khinast, J. G., Oct 2017, In : Advanced powder technology. 28, 10, p. 2465-2481

Research output: Contribution to journalArticle

2011

Continuous Annular Electro-Chromatography - a preparative multidimensional separation system for APIs

Braunbruck, M-G., Gruber-Wölfler, H., Feenstra, P., Laskowski, R., Bart, H-J. & Khinast, J., 2011.

Research output: Contribution to conferencePoster

2012

Modeling of Co-Rotating Twin Screw Extrusion

Eitzlmayr, A. & Khinast, J., 2012, 8. Minisymposium Verfahrenstechnik, 2. Mai 2012, JKU Linz, Book of Abstracts. Linz: Verlag der Johannes Kepler Unversität Linz, p. 94-98

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2014

The influence of water on the solid state properties of freeze dried proteins

Wahl, V., Leitgeb, S. & Khinast, J., 2014.

Research output: Contribution to conferencePoster

2013

The effect of capsule-filling machine vibrations on average fill weight

Llusa, M., Faulhammer, E., Khinast, J., Lawrence, S., Biserni, S. & Calzolari, V., 2013, In : International Journal of Pharmaceutics. 454, 1, p. 381–387

Research output: Contribution to journalArticle

2012

Small- and wide-angle X-ray scattering (SWAXS) for quantification of aspirin content in a binary powder mixture.

Hodzic, A., Llusa, M., Fraser, S., Scheibelhofer, O., Koller, D., Reiter, F., Laggner, P. & Khinast, J., 2012, In : International Journal of Pharmaceutics. 428, 1-2, p. 91-95

Research output: Contribution to journalArticle

2018

Flow of granular materials in a bladed mixer: Effect of particle properties and process parameters on impeller torque and power consumption

Boonkanokwong, V., Frank, R. P., Valliappan, P., Remy, B., Khinast, J. G. & Glasser, B. J., 1 Nov 2018, In : Advanced powder technology. 29, 11, p. 2733-2752 20 p.

Research output: Contribution to journalArticle

Hopper flow of irregularly shaped particles (non-convex polyhedra): GPU-based DEM simulation and experimental validation

Khinast, J., Govender, N., Wilke, D. N., Wu, C-Y., Pizette, P. & Xu, W., 2018, In : Chemical Engineering Science. p. 34-51

Research output: Contribution to journalArticle

2019

Drying of supported catalysts for high metal concentrations: A reduced parameter model

Noorithaya, A. V., Bishop, C., Sarkar, P., Khinast, J. G. & Glasser, B. J., 12 Oct 2019, In : Chemical Engineering Science. 206, p. 361-374 14 p.

Research output: Contribution to journalArticle

2012

Reversed phase monolithic stationary phases for defined separation tasks in Continuous Annular Electro-Chromatography

Braunbruck, M-G., Gruber-Wölfler, H., Feenstra, P., Khinast, J., Laskowski, R. & Bart, H-J., 2012, Book of Abstracts. Linz: ., p. 92-93

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Funktionalisierte mesoporöse Monolithen für kontinuierliche Ringspalt-Elektrochromatographie

Braunbruck, M-G., Gruber-Wölfler, H., Feenstra, P., Laskowski, R., Bart, H-J. & Khinast, J., 2012, In : Chemie - Ingenieur - Technik. 84, 8, p. 1400

Research output: Contribution to journalArticle

2012

Continuous Pharmaceutical Hot-Melt Extrusion & Hot-Die Face Pelletizing

Treffer, D. F., Eitzlmayr, A., Smola, C-M., Koscher, G., Roblegg, E. & Khinast, J., 28 Oct 2012.

Research output: Contribution to conference(Old data) Lecture or Presentation

2014

A Novel Simulation Approach for Hot Melt Extrusion

Eitzlmayr, A., Matic, J., Koscher, G. & Khinast, J., 16 Jun 2014.

Research output: Contribution to conference(Old data) Lecture or Presentation

2012

Demonstration of a Pharmaceutical Hot Melt Extrusion Process with SIPAT

Markl, D., Kavsek, B., Wahl, P., Koller, D., Francois, K. & Khinast, J., 22 Jan 2012.

Research output: Contribution to conference(Old data) Lecture or Presentation

2019

Computational Fluid Dynamics-Discrete Element Method Modeling of an Industrial-Scale Wurster Coater

Boehling, P., Khinast, J. G., Jajcevic, D., Davies, C., Carmody, A., Doshi, P., Ende, M. T. A. & Sarkar, A., Jan 2019, In : Journal of Pharmaceutical Sciences . 108, 1, p. 538-550

Research output: Contribution to journalArticle

2013

Laterally Controlled Immobilization Of Organometallic Pd-Catalysts On Flat and Porous Si-Wafers

Lichtenegger, G. J., Gruber-Wölfler, H. & Khinast, J., 23 Sep 2013.

Research output: Contribution to conference(Old data) Lecture or Presentation

2012

Separation, hydrodynamics and heating effects in continuous annular electro-chromatography (CAEC)

Laskowski, R., Bart, H-J., Hofmann, C., Menges, G., Werner, B., Frese, I., Löb, P., Braunbruck, M-G., Gruber-Wölfler, H., Feenstra, P. & Khinast, J., 25 Aug 2012.

Research output: Contribution to conference(Old data) Lecture or Presentation

2011

Formation of O/W Emulsions by Static Mixers and Production of Microparticles for Pharmaceutical Applications

Kiss, N., Brenn, G., Pucher, H., Wieser, J., Scheler, S., Jennewein, H., Suzzi, D. & Khinast, J., 20 Oct 2011.

Research output: Contribution to conference(Old data) Lecture or Presentation

2013

Nano-Extrusion (NANEX): A One-step Process for Manufacturing Solid API Nanoparticle-Formulations Directly from the Liquid Phase

Baumgartner, R., Khinast, J. & Roblegg, E., 2013.

Research output: Contribution to conferencePoster

2011

Optimization of Tablet Coating Processes using Discrete Element Method Simulations

Toschkoff, G., Suzzi, D., Just, S., Knop, K., Funke, A., Altmeyer, A., Khinast, J. & Kleinebudde, P., 2011.

Research output: Contribution to conferencePoster

2014

How does alcohol impact hot-melt extruded pellets comprising solid lipids as functional additives?

Jedinger, N., Khinast, J. & Roblegg, E., 2014.

Research output: Contribution to conferencePoster

2017

Crystal Engineering in Continuous Plug-Flow Crystallizers

Neugebauer, P., Besenhard, M., Khinast, J. & Scheibelhofer, O., 10 Oct 2017, In : Crystal Growth and Design.

Research output: Contribution to journalArticle

2018

Study of a low-dose capsule filling process by dynamic and static tests for advanced process understanding

Paudel, A., Stranzinger, S., Faulhammer, E., Scheibelhofer, O., Calzolari, V., Biserni, S. & Khinast, J., 5 Apr 2018, In : International Journal of Pharmaceutics. 540, 1-2, p. 22-30 8 p.

Research output: Contribution to journalArticle

2014

Real-time data processing for in-line monitoring of a pharmaceutical coating process by optical coherence tomography

Markl, D., Ziegler, J., Hannesschläger, G., Sacher, S., Buchsbaum, A., Leitner, M. & Khinast, J., 2014, Biophotonics: Photonic Solutions for Better Health Care IV. ., Vol. 9129. p. 1-12 (Proceeding of SPIE).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Characterization of the coating and tablet core roughness by means of 3D optical coherence tomography

Khinast, J., Markl, D., Wahl, P., Pichler, H. & Sacher, S., 2018, In : International Journal of Pharmaceutics. p. 459-466

Research output: Contribution to journalArticle