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  • 2019
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  • 2016

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  • Johannes Khinast
2018

Mechanical strength of microspheres produced by drying of acoustically levitated suspension droplets

Kreimer, M., Aigner, I., Sacher, S., Krumme, M., Mannschott, T., van der Wel, P., Kaptein, A., Schröttner, H., Brenn, G. & Khinast, J., 2018, In : Powder Technology. 325, p. 247-260

Research output: Contribution to journalArticle

RTD-based Material Tracking in a Fully-Continuous Dry Granulation Tableting Line

Martinetz, M., Kartunnen, A-P., Sacher, S., Wahl, P., Ketolainen, J., Khinast, J. & Korhonnen, O., 5 Jun 2018.

Research output: Contribution to conferencePaper

Open Access
2019

Heat transfer of dry granular materials in a bladed mixer: Effect of thermal properties and agitation rate

Hartmanshenn, C., Khinast, J. G., Papageorgiou, C. D., Mitchell, C., Quon, J. & Glasser, B. J., 27 Nov 2019, In : AIChE Journal.

Research output: Contribution to journalArticle

2016

The Effect of Powder and Process Parameters on the Powder Bed Uniformity of a low-dose Capsule Filling Process

Stranzinger, S., Faulhammer, E., Srčič, S., Dreu, R., Calzolari, V., Biserni, S., Paudel, A. & Khinast, J., 7 Jul 2016.

Research output: Contribution to conference(Old data) Lecture or Presentation

Optimization of a Micro-Feeding Unit in a Continuous Pharmaceutical Process Line

Hörmann, T., Tausendschön, J., Schmid, T., Koscher, G. & Khinast, J., 21 Apr 2016.

Research output: Contribution to conferencePoster

2019

Shedding light on coatings: Real-time monitoring of coating quality at industrial scale

Sacher, S., Wahl, P., Weissensteiner, M., Wolfgang, M., Pokhilchuk, Y., Looser, B., Thies, J., Raffa, A. & Khinast, J. G., 20 Jul 2019, In : International Journal of Pharmaceutics. 566, p. 57-66

Research output: Contribution to journalArticle

2016

NANEX: Process design and optimization

Baumgartner, R., Matic, J., Schrank, S., Laske, S., Khinast, J. & Roblegg, E., 14 Apr 2016, In : International Journal of Pharmaceutics. 506, p. 35-45 10 p.

Research output: Contribution to journalArticle

2018

Numerical investigation of a coarse-grain discrete element method in solid mixing in a spouted bed

Takabatake, K., Mori, Y., Khinast, J. G. & Sakai, M., 15 Aug 2018, In : Chemical Engineering Journal. 346, p. 416-426 11 p.

Research output: Contribution to journalArticle

2016

Real-Time Monitoring and Ejection of out-of-Spec Tablets Via NIR Chemical Imaging

Wolfgang, M., Wahl, P., Hauseder, G., Sacher, S., Kerschhaggl, M. & Khinast, J., 14 Nov 2016.

Research output: Contribution to conferencePoster

Decoupling of a Low-Dose Dosator Capsule Filling Process in Dynamic and Static Mode Tests to Understand the Extend of the Effect of Powder and Process Parameters on Capsule Quality Attributes

Faulhammer, E., Stranzinger, S., Loidolt, P., Calzolari, V., Biserni, S., Srčič, S., Dreu, R., Paudel, A. & Khinast, J., 18 Nov 2016.

Research output: Contribution to conference(Old data) Lecture or Presentation

2017

Continuous monitoring of API content, API distribution and crushing strength after tableting via near-infrared chemical imaging

Wahl, P. R., Pucher, I., Scheibelhofer, O., Kerschhaggl, M., Sacher, S. & Khinast, J. G., 25 Feb 2017, In : International Journal of Pharmaceutics. 518, 1-2, p. 130-137

Research output: Contribution to journalArticle

Mechansitic modeling of a capsule filling process

Loidolt, P., Madlmeir, S. & Khinast, J., 30 Oct 2017, In : International Journal of Pharmaceutics.

Research output: Contribution to journalArticle

2019

Deriving control parameter settings from process models to control capsule fillers integrated into continuous manufacturing

Wagner, B., Cheong, S. F., Brinz, T. & Khinast, J., 2 Sep 2019, In : Drug Development and Industrial Pharmacy. 45, 9, p. 1523-1536

Research output: Contribution to journalArticle

2016

Effect of Bubble-Particle Interaction Models on Flow Predictions in Three-Phase Bubble Columns

Gruber, M. C., Radl, S. & Khinast, J., 26 Feb 2016, In : Chemical Engineering Science. 146, p. 226–243

Research output: Contribution to journalArticle

Open Access
2019

Drying of supported catalysts for high metal concentrations: A reduced parameter model

Noorithaya, A. V., Bishop, C., Sarkar, P., Khinast, J. G. & Glasser, B. J., 12 Oct 2019, In : Chemical Engineering Science. 206, p. 361-374 14 p.

Research output: Contribution to journalArticle

2017

Influence of Process Route on the Mechanical Properties of Polymer Based Intravaginal Drug Delivery Systems

Eggenreich, K., Schrank, S., Koscher, G., Nickisch, K., Roblegg, E. & Khinast, J., 2017, In : AIP Conference Proceedings. 1914

Research output: Contribution to journalArticle

2019

Particle-level residence time data in a twin-screw feeder

Toson, P. & Khinast, J. G., Dec 2019, In : Data in Brief . 27, 104672

Research output: Contribution to journalArticle

2018
2017

NUMERICAL STUDY ON THE EFFECT OF PARTICLE SHAPE ON MIXERS

Govender, N., Wilke, D. N., Rajamani, R. K., Pizette, P., Khinast, J. & Glasser, B. J., 2017

Research output: Other contribution

2019

Prediction of the anisotropic mechanical properties of compacted powders

Loidolt, P., Ulz, M. H. & Khinast, J., 2019, In : Powder Technology. 345, p. 589-600 12 p.

Research output: Contribution to journalArticle

2017

Continuous Manufacturing of Pharmaceuticals: Chapter 10 - Continuous Melt Extrusion and Direct Pelletization

Laske, S., Hörmann, T., Witschnigg, A., Koscher, G., Wahl, P., Hsiao, W. K. & Khinast, J., 2017, 1st ed. NJ, USA: Wiley & Sons. 337 p. (Advances in Pharmaceutical Technology; vol. Continuous Manufacturing of Pharmaceuticals, no. 1)

Research output: Book/ReportBook

Why Hot Melts Do Not Stick to Cold Surfaces

Treffer, D. F. & Khinast, J. G., Oct 2017, In : Polymer Engineering and Science. 57, 10, p. 1083-1089

Research output: Contribution to journalArticle

2016

The Virtual Sandbox: Particle Flow Physics taught with Interactive Tools

Radl, S., Wu, M., Redlinger-Pohn, J. D., Wachtler, L., Bahar, B., Khinast, J., Eck, J. & Reichel, E., 14 Nov 2016.

Research output: Contribution to conference(Old data) Lecture or Presentation

Open Access
File
2019

Using online content uniformity measurements for rapid automated process development exemplified via an X-ray system

Wagner, B., Brinz, T. & Khinast, J., 3 Jul 2019, In : Pharmaceutical development and technology. 24, 6, p. 775-787

Research output: Contribution to journalArticle

2018

Control of three different continuous pharmaceutical manufacturing processes: Use of soft sensors

Rehrl, J., Kartunnen, A-P., Nicolaï, N., Hörmann, T., Horn, M., Korhonnen, O., Nopens, I., de Beer, T. & Khinast, J., 30 May 2018, In : International Journal of Pharmaceutics. 543, 1-2, p. 60-72

Research output: Contribution to journalArticle

The Effect of Liquid Bridge Model Details on the Dynamics of Wet Fluidized Beds

Wu, M., Khinast, J. & Radl, S., Feb 2018, In : AIChE Journal. 64, p. 437-456 10.1002/aic.15947.

Research output: Contribution to journalArticle

2017

Crystal Engineering in Continuous Plug-Flow Crystallizers

Neugebauer, P., Besenhard, M., Khinast, J. & Scheibelhofer, O., 10 Oct 2017, In : Crystal Growth and Design.

Research output: Contribution to journalArticle

2016

Light in Powder - Penetration and Information

Scheibelhofer, O., Wahl, P., Larchevêque, B. & Khinast, J., 21 Mar 2016.

Research output: Contribution to conferencePoster

Local gas holdup simulation and validation of industrial-scale aerated bioreactors

Witz, C., Treffer, D. F., Hardiman, T. & Khinast, J., 2 Oct 2016, In : Chemical Engineering Science. 152, p. 636-648 13 p.

Research output: Contribution to journalArticle

2019

Computational Fluid Dynamics-Discrete Element Method Modeling of an Industrial-Scale Wurster Coater

Boehling, P., Khinast, J. G., Jajcevic, D., Davies, C., Carmody, A., Doshi, P., Ende, M. T. A. & Sarkar, A., Jan 2019, In : Journal of Pharmaceutical Sciences . 108, 1, p. 538-550

Research output: Contribution to journalArticle

2017

Liquid Transport Rates during Binary Collisions of Unequally-sized Particles

Wu, M., Khinast, J. & Radl, S., 2017, In : Powder Technology. 309, p. 95-109 14 p.

Research output: Contribution to journalArticle

Open Access
File

A Review of PAT Strategies in Secondary Solid Oral Dosage Manufacturing of Small Molecules

Laske, S., Paudel, A., Scheibelhofer, O., Sacher, S., Hörmann, T. & Khinast, J., Mar 2017, In : Journal of Pharmaceutical Sciences . 106, 3, p. 667-712 45 p.

Research output: Contribution to journalArticle

2018

Understanding the motion of hard shell capsules in dry powder inhalers

Benque, B. & Khinast, J., 5 Nov 2018.

Research output: Contribution to conferencePoster

2016

Multi-methodological investigation of the variability of the microstructure of HPMC hard capsules

Faulhammer, E., Khinast, J., Paudel, A., Wahl, V. & Markl, D., 25 Sep 2016, In : International Journal of Pharmaceutics. 511, 2, p. 840-854 14 p.

Research output: Contribution to journalArticle

2019

Model-based approach to the design of pharmaceutical roller-compaction processes

Toson, P., Lopes, D. G., Paus, R., Kumar, A., Geens, J., Stibale, S., Quodbach, J., Kleinebudde, P., Hsiao, W-K. & Khinast, J., Dec 2019, In : International Journal of Pharmaceutics: X. 1, 100005.

Research output: Contribution to journalArticle

Open Access

Tribo-Charging Behaviour of Inhalable Mannitol Blendswith Salbutamol Sulphate

Zellnitz, S., Pinto, J., Brunsteiner, M., Schröttner, H., Khinast, J. & Paudel, A., 2019, In : Pharmaceutical research. 36, 6, p. 80 11 p., 36:80.

Research output: Contribution to journalArticle

2018

Study of a low-dose capsule filling process by dynamic and static tests for advanced process understanding

Paudel, A., Stranzinger, S., Faulhammer, E., Scheibelhofer, O., Calzolari, V., Biserni, S. & Khinast, J., 5 Apr 2018, In : International Journal of Pharmaceutics. 540, 1-2, p. 22-30 8 p.

Research output: Contribution to journalArticle

2016
2019
Open Access
2016

NIR-Hyperspectral Imaging and Raman Chemical Mapping of Multilayer-Tablets

Poms, J., Scheibelhofer, O., Sacher, S. & Khinast, J., 30 Mar 2016.

Research output: Contribution to conferencePoster

2019

Performance Characterization of Static Mixers in Precipitating Environments

Kreimer, M., Zettl, M., Aigner, I., Mannschott, T., van der Wel, P., Khinast, J. G. & Krumme, M., Jul 2019, In : Organic Process Research & Devlopment. 23, 7, p. 1308-1320

Research output: Contribution to journalArticle

Predicting capsule fill weight from in-situ powder density measurements using terahertz reflection technology

Stranzinger, S., Faulhammer, E., Li, J., Dong, R., Zeitler, J. A., Biserni, S., Calzolari, V., Khinast, J. G. & Markl, D., 1 Dec 2019, In : International Journal of Pharmaceutics: X. 1, 100004.

Research output: Contribution to journalArticle

Open Access
2017
2016

Speed change experiments in a rotary tablet press

Martinetz, M., Aigner, I., Rehrl, J., Sacher, S. & Khinast, J., 3 Oct 2016.

Research output: Contribution to conferencePoster

2017

Drug–Excipient Interactions in the Solid State: The Role of Different Stress Factors

Gressl, C., Brunsteiner, M., Davis, A., Landis, M., Pencheva, K., Scrivens, G., Sluggett, G. W., Wood, G. P. F., Gruber-Wölfler, H., Khinast, J. & Paudel, A., 2 Nov 2017, In : Molecular pharmaceutics. 14, 12, p. 4560-4571 11 p.

Research output: Contribution to journalArticle