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  • Johannes Khinast
2017

Crystal Engineering in Continuous Plug-Flow Crystallizers

Neugebauer, P., Besenhard, M., Khinast, J. & Scheibelhofer, O., 10 Oct 2017, In : Crystal Growth and Design.

Research output: Contribution to journalArticle

DEM study of granular transport in partially filled horizontal screw conveyors

Orefice, L. & Khinast, J. G., Jan 2017, In : Powder Technology. 305, p. 347-356

Research output: Contribution to journalArticle

Drug–Excipient Interactions in the Solid State: The Role of Different Stress Factors

Gressl, C., Brunsteiner, M., Davis, A., Landis, M., Pencheva, K., Scrivens, G., Sluggett, G. W., Wood, G. P. F., Gruber-Wölfler, H., Khinast, J. & Paudel, A., 2 Nov 2017, In : Molecular pharmaceutics. 14, 12, p. 4560-4571 11 p.

Research output: Contribution to journalArticle

Efficient Discrete Element Method Simulation Strategy for Analyzing Large-Scale Agitated Powder Mixers

Siegmann, E., Jajcevic, D., Radeke, C., Strube, D., Friedrich, K. & Khinast, J. G., 1 Aug 2017, In : Chemie - Ingenieur - Technik. 89, 8, p. 995-1005 11 p.

Research output: Contribution to journalArticle

Establishment of a Molding Procedure to Facilitate Formulation Development for Co-extrudates

Eder, S., Beretta, M., Witschnigg, A., Koutsamanis, I., Eggenreich, K., Khinast, J. G., Koscher, G., Paudel, A., Nickisch, K., Friedrich, M., Froehlich, E. & Roblegg, E., 1 Nov 2017, In : AAPS PharmSciTech . 18, 8, p. 2971-2976 6 p.

Research output: Contribution to journalArticle

Influence of Process Route on the Mechanical Properties of Polymer Based Intravaginal Drug Delivery Systems

Eggenreich, K., Schrank, S., Koscher, G., Nickisch, K., Roblegg, E. & Khinast, J., 2017, In : AIP Conference Proceedings. 1914

Research output: Contribution to journalArticle

Liquid Transport Rates during Binary Collisions of Unequally-sized Particles

Wu, M., Khinast, J. & Radl, S., 2017, In : Powder Technology. 309, p. 95-109 14 p.

Research output: Contribution to journalArticle

Open Access
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Mechanistic modeling of a capsule filling process

Loidolt, P., MadImeir, S. & Khinast, J. G., 30 Oct 2017, In : International Journal of Pharmaceutics. 532, 1, p. 47-54

Research output: Contribution to journalArticle

Mechansitic modeling of a capsule filling process

Loidolt, P., Madlmeir, S. & Khinast, J., 30 Oct 2017, In : International Journal of Pharmaceutics.

Research output: Contribution to journalArticle

Micro-feeding and dosing of powders via a small-scale powder pump

Besenhard, M., Fathollahi, S., Siegmann, E., Slama, E., Faulhammer, E. & Khinast, J., 2017, In : International Journal of Pharmaceutics. 519, 1-2, p. 314-322

Research output: Contribution to journalArticle

NUMERICAL STUDY ON THE EFFECT OF PARTICLE SHAPE ON MIXERS

Govender, N., Wilke, D. N., Rajamani, R. K., Pizette, P., Khinast, J. & Glasser, B. J., 2017

Research output: Other contribution

Suzuki-Miyaura coupling reactions using novel metal oxide supported ionic palladium catalysts

Lichtenegger, G. J., Maier, M., Hackl, M., Khinast, J. G., Goessler, W., Griesser, T., Kumar, V. S. P., Gruber-Woelfler, H. & Deshpande, P. A., Jan 2017, In : Journal of molecular catalysis / A. 426, p. 39-51

Research output: Contribution to journalArticle

Why Hot Melts Do Not Stick to Cold Surfaces

Treffer, D. F. & Khinast, J. G., Oct 2017, In : Polymer Engineering and Science. 57, 10, p. 1083-1089

Research output: Contribution to journalArticle

2018

3D printing of oral drugs: a new reality or hype?

Hsiao, W. K., Lorber, B., Reitsamer, H. & Khinast, J., 2 Jan 2018, In : Expert opinion on drug delivery. 15, 1, p. 1-4 4 p.

Research output: Contribution to journalEditorial

A combined DEM & FEM approach for modelling roll compaction process

Mazor, A., Orefice, L., Michrafy, A., de Ryck, A. & Khinast, J. G., Sep 2018, In : Powder Technology. 337, p. 3-16 14 p.

Research output: Contribution to journalArticle

Automation of a dosing-disc capsule filler from the perspective of reliability and safety

Wagner, B., Brinz, T., Otterbach, S. & Khinast, J., 4 Mar 2018, In : Drug Development and Industrial Pharmacy. 44, 3, p. 502-510 9 p.

Research output: Contribution to journalArticle

Characterization of the coating and tablet core roughness by means of 3D optical coherence tomography

Khinast, J., Markl, D., Wahl, P., Pichler, H. & Sacher, S., 2018, In : International Journal of Pharmaceutics. p. 459-466

Research output: Contribution to journalArticle

Continuous Drying of Pharmaceutical Powders Using a Twin-Screw Extruder

Kreimer, M., Aigner, I., Lepek, D. & Khinast, J., 20 Jul 2018, In : Organic Process Research & Devlopment. 22, 7, p. 813-823 11 p.

Research output: Contribution to journalArticle

Control of three different continuous pharmaceutical manufacturing processes: Use of soft sensors

Rehrl, J., Kartunnen, A-P., Nicolaï, N., Hörmann, T., Horn, M., Korhonnen, O., Nopens, I., de Beer, T. & Khinast, J., 30 May 2018, In : International Journal of Pharmaceutics. 543, 1-2, p. 60-72

Research output: Contribution to journalArticle

Crystal Shape Modification via Cycles of Growth and Dissolution in a Tubular Crystallizer

Neugebauer, P., Besenhard, M., Peter, A., Gruber-Wölfler, H. & Khinast, J., 15 Jun 2018, In : Crystal Growth and Design. 18, 8, p. 4403-4415

Research output: Contribution to journalArticle

Detailed modeling and process design of an advanced continuous powder mixer

Toson, P., Siegmann, E., Trogrlic, M., Kureck, H., Khinast, J., Jajcevic, D., Doshi, P., Blackwood, D., Bonnassieux, A., Daugherity, P. D. & am Ende, M. T., 1 Dec 2018, In : International Journal of Pharmaceutics. 552, 1-2, p. 288-300 13 p.

Research output: Contribution to journalArticle

Effect of particle shape in grinding mills using a GPU based DEM code

Khinast, J., Govender, N., Rajamani, R. K., Wilke, D. N., Wu, C-Y. & Glasser, B. J., 2018, In : Minerals engineering. p. 71-84

Research output: Contribution to journalArticle

Flow of granular materials in a bladed mixer: Effect of particle properties and process parameters on impeller torque and power consumption

Boonkanokwong, V., Frank, R. P., Valliappan, P., Remy, B., Khinast, J. G. & Glasser, B. J., 1 Nov 2018, In : Advanced powder technology. 29, 11, p. 2733-2752 20 p.

Research output: Contribution to journalArticle

Hopper flow of irregularly shaped particles (non-convex polyhedra): GPU-based DEM simulation and experimental validation

Khinast, J., Govender, N., Wilke, D. N., Wu, C-Y., Pizette, P. & Xu, W., 2018, In : Chemical Engineering Science. p. 34-51

Research output: Contribution to journalArticle

In-line measurement of residence time distribution in melt extrusion via video analysis

Wahl, P. R., Hörl, G., Kaiser, D., Sacher, S., Rupp, C., Shlieout, G., Breitenbach, J., Koscher, G. & Khinast, J. G., 1 Feb 2018, In : Polymer Engineering and Science. 58, 2, p. 170-179 10 p.

Research output: Contribution to journalArticle

Large-scale GPU based DEM modeling of mixing using irregularly shaped particles

Khinast, J., Govender, N., Wilke, D. N., Wu, C-Y., Rajamani, R. K. & Glasser, B. J., 2018, In : Advanced powder technology. p. 2476-2490

Research output: Contribution to journalArticle

Manufacturing classification system in the real world: factors influencing manufacturing process choices for filed commercial oral solid dosage formulations, case studies from industry and considerations for continuous processing

Khinast, J., Leane, M., Pitt, K., Reynolds, G. K., Dawson, N., Ziegler, I., Szepes, A., Crean, A. M., Agnol, R. D., Broegmann, B., Charlton, S., Davies, C., Gamble, J., Gamlen, M., Hsiao, W. K., Khimyak, Y., Kleinebudde, P., Moreton, C., Oswald, M., Page, S. & 5 others, Paudel, A., Sahoo, R., Sheehan, S., Stamato, H. & Stone, E., 2018, In : Pharmaceutical development and technology. p. 964-977 13 p.

Research output: Contribution to journalArticle

Mechanical strength of microspheres produced by drying of acoustically levitated suspension droplets

Kreimer, M., Aigner, I., Sacher, S., Krumme, M., Mannschott, T., van der Wel, P., Kaptein, A., Schröttner, H., Brenn, G. & Khinast, J., 2018, In : Powder Technology. 325, p. 247-260

Research output: Contribution to journalArticle

Numerical investigation of a coarse-grain discrete element method in solid mixing in a spouted bed

Takabatake, K., Mori, Y., Khinast, J. G. & Sakai, M., 15 Aug 2018, In : Chemical Engineering Journal. 346, p. 416-426 11 p.

Research output: Contribution to journalArticle

Rapid automated process development of a continuous capsule-filling process

Wagner, B., Brinz, T., Otterbach, S. & Khinast, J., 30 Jul 2018, In : International Journal of Pharmaceutics. 546, 1-2, p. 154-165 12 p.

Research output: Contribution to journalArticle

Open Access

RTD-based Material Tracking in a Fully-Continuous Dry Granulation Tableting Line

Martinetz, M., Kartunnen, A-P., Sacher, S., Wahl, P., Ketolainen, J., Khinast, J. & Korhonnen, O., 5 Jun 2018.

Research output: Contribution to conferencePaper

Open Access

Spatially Resolved Spectral Powder Analysis: Experiments and Modeling

Khinast, J., Scheibelhofer, O., Wahl, P., Larchevêque, B. & Chauchard, F., 2018, In : Applied Spectroscopy. p. 521-534

Research output: Contribution to journalArticle

Study of a low-dose capsule filling process by dynamic and static tests for advanced process understanding

Paudel, A., Stranzinger, S., Faulhammer, E., Scheibelhofer, O., Calzolari, V., Biserni, S. & Khinast, J., 5 Apr 2018, In : International Journal of Pharmaceutics. 540, 1-2, p. 22-30 8 p.

Research output: Contribution to journalArticle

The Effect of Liquid Bridge Model Details on the Dynamics of Wet Fluidized Beds

Wu, M., Khinast, J. & Radl, S., Feb 2018, In : AIChE Journal. 64, p. 437-456 10.1002/aic.15947.

Research output: Contribution to journalArticle

The effect of saliva on the fate of nanoparticles

Teubl, B. J., Stojkovic, B., Docter, D., Pritz, E., Leitinger, G., Poberaj, I., Prassl, R., Stauber, R. H., Fröhlich, E., Khinast, J. G. & Roblegg, E., 1 Mar 2018, In : Clinical Oral Investigations. 22, 2, p. 929-940 12 p.

Research output: Contribution to journalArticle

Understanding the motion of hard shell capsules in dry powder inhalers

Benque, B. & Khinast, J., 5 Nov 2018.

Research output: Contribution to conferencePoster