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Author

  • Anton Glieder
2019

Capsaicin Metabolite Synthesis by Fungal Cytochrome P450

Willim, M., Bachler, T., Schweda, B., Migglautsch, A. K., Glieder, A., Breinbauer, R. & Winkler, M., 14 Feb 2019.

Research output: Contribution to conferencePosterResearch

Current advances in engineering tools for Pichia pastoris

Fischer, J. E. & Glieder, A., 1 Oct 2019, In : Current opinion in biotechnology. 59, p. 175-181 7 p.

Research output: Contribution to journalReview articleResearchpeer-review

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., Nov 2019.

Research output: Contribution to conferencePosterResearch

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., Apr 2019.

Research output: Contribution to conferencePosterResearch

Cytochrome P450 mediated hydroxylation of ibuprofen using Pichia pastoris as biocatalyst

Rinnofner, C., Kerschbaumer, B., Weber, H., Glieder, A. & Winkler, M., 2019, In : Biocatalysis and Agricultural Biotechnology. 17, p. 525-528 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Human drug metabolite synthesis catalysed by recombinant P450 enzymes

Glieder, A., Weninger, A., Schmid, C., Rinnofner, C., Winkler, M., Müller, M., Schürmann, M., Woodley, J., Valero, F., Garcia-Ortega, X., Fürst, M. J. L. J. & Fraaije, M. W., Jun 2019.

Research output: Contribution to conferenceAbstractResearch

Methanol Independent Expression by Pichia Pastoris Employing De-repression Technologies

Fischer, J. E., Hatzl, A-M., Weninger, A., Schmid, C. & Glieder, A., 2019, In : Journal of Visualized Experiments . 2019, 143, e58589.

Research output: Contribution to journalArticleResearchpeer-review

Single-cell approach to monitor the unfolded protein response during biotechnological processes with Pichia pastoris

Raschmanová, H., Zamora, I., Borčinová, M., Meier, P., Weninger, A., Mächler, D., Glieder, A., Melzoch, K., Knejzlík, Z. & Kovar, K., 1 Jan 2019, In : Frontiers in Microbiology . 10, FEB, 335.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2018

Aliphatic hydroxylation and epoxidation of capsaicin by Cytochrome P450 CYP505X

Migglautsch, A. K., Willim, M., Schweda, B., Glieder, A., Breinbauer, R. & Winkler, M., 31 Aug 2018, In : Tetrahedron. 74, p. 6199-6204

Research output: Contribution to journalArticleResearchpeer-review

Combinatorial optimization strategies to increase Human P450 catalytic Activity in whole cell

Weninger, A., Alkofer, A., Schmid, C., Bitter, J., Volpini de Maestri, A., Pranjic, M., Winkler, M. & Glieder, A., Sep 2018.

Research output: Contribution to conferencePosterResearch

Construction of a cellulose-metabolizing Komagataella phaffii (Pichia pastoris) by co-expressing glucanases and β-glucosidase

Kickenweiz, T., Glieder, A. & Wu, J. C., 2018, In : Applied Microbiology and Biotechnology. 102, 3, p. 1297-1306

Research output: Contribution to journalArticleResearchpeer-review

Engineered bidirectional promoters enable rapid multi-gene co-expression optimization

Vogl, T., Kickenweiz, T., Pitzer, J., Sturmberger, L., Weninger, A., Biggs, B. W., Köhler, E-M., Baumschlager, A., Fischer, J. E., Hyden, P., Wagner, M., Baumann, M., Borth, N., Geier, M., Ajikumar, P. K. & Glieder, A., 4 Sep 2018, In : Nature Communications. 9, 1, p. 3589

Research output: Contribution to journalArticleResearchpeer-review

Erratum to: Engineered bidirectional promoters enable rapid multi-gene co-expression optimization (Nature Communications, (2018), 9, 1, (3589), 10.1038/s41467-018-05915-w)

Vogl, T., Kickenweiz, T., Pitzer, J., Sturmberger, L., Weninger, A., Biggs, B. W., Köhler, E. M., Baumschlager, A., Fischer, J. E., Hyden, P., Wagner, M., Baumann, M., Borth, N., Geier, M., Ajikumar, P. K. & Glieder, A., 1 Dec 2018, In : Nature Communications. 9, 1, 4566.

Research output: Contribution to journalComment/debateResearchpeer-review

Humane Enzyme für die Organische Synthese

Winkler, M., Geier, M., Hanlon, S. P., Nidetzky, B. & Glieder, A., 2018, In : Angewandte Chemie. 130, p. 13592-13610

Research output: Contribution to journalReview articleResearchpeer-review

Human Enzymes for Organic Synthesis

Winkler, M., Geier, M., Hanlon, S. P., Nidetzky, B. & Glieder, A., 2018, In : Angewandte Chemie / International Edition . 57, 41, p. 13406-13423 18 p.

Research output: Contribution to journalReview articleResearchpeer-review

Implementing CRISPR-Cas technologies in conventional and non-conventional yeasts: Current state and future prospects

Raschmanová, H., Weninger, A., Glieder, A., Kovar, K. & Vogl, T., 1 May 2018, In : Biotechnology Advances. 36, 3, p. 641-665 25 p.

Research output: Contribution to journalReview articleResearchpeer-review

Methanol independent induction in Pichia pastoris by simple derepressed overexpression of single transcription factors

Vogl, T., Sturmberger, L., Fauland, P. C., Hyden, P., Fischer, J. E., Schmid, C., Thallinger, G. G., Geier, M. & Glieder, A., 1 Apr 2018, In : Biotechnology and Bioengineering. 115, 4, p. 1037-1050

Research output: Contribution to journalArticleResearchpeer-review

Parallelized biocatalytic scanning probe lithography for the additive fabrication of conjugated polymer structures

Hosford, J., Valles, M., Krainer, F. W., Glieder, A. & Wong, L. S., 2018, In : Nanoscale. 10, 15, p. 7185-7193 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Production of Hydroxynitrile Lyase from Davallia tyermannii (DtHNL) in Komagataella phaffii and Its Immobilization as a CLEA to Generate a Robust Biocatalyst

Lanfranchi, E., Grill, B., Raghoebar, Z., Van Pelt, S., Sheldon, R. A., Steiner, K., Glieder, A. & Winkler, M., 2018, In : ChemBioChem. 19, 4, p. 312-316 10.1002/cbic.201700419.

Research output: Contribution to journalArticleResearchpeer-review

The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases

Fiorentini, F., Hatzl, A-M., Schmidt, S., Savino, S., Glieder, A. & Mattevi, A., 2018, In : Biochemistry. 57, 48, p. 6701-6714

Research output: Contribution to journalArticleResearchpeer-review

2017

Chemicals made by Pichia pastoris

Glieder, A., 1 Nov 2017.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Cloning and upscale production of monoamine oxidase N (MAO-N D5) by Pichia pastoris

Markošová, K., Camattari, A., Rosenberg, M., Glieder, A., Turner, N. J. & Rebroš, M., 2017, In : Biotechnology Letters. https://doi.org/10.1007/s10529-017-2450-y.

Research output: Contribution to journalArticleResearchpeer-review

Combinatorial optimization strategies to increase Human P450 catalytic Activity in whole cell Biotransformations

Weninger, A., Alkofer, A., Schmid, C., Pranjic, M., Winkler, M. & Glieder, A., Jul 2017.

Research output: Contribution to conferencePosterResearch

Concurrent optimization strategies for high level protein production: Process, strain and expression engineering

Weninger, A., Alkofer, A., Schmid, C., Höppel, E., Winkler, M. & Glieder, A., Jun 2017.

Research output: Contribution to conferencePosterResearch

Cytochrome P450 CYP505 mutants for biooxidations of active pharmaceutical ingredients

Bachler, T., Weninger, A., Glieder, A. & Winkler, M., 5 Sep 2017.

Research output: Contribution to conferencePosterResearch

Cytochrome P450 CYP505 mutants for biooxidations of active pharmaceutical ingredients

Bachler, T., Weninger, A., Glieder, A. & Winkler, M., 21 Nov 2017.

Research output: Contribution to conferencePosterResearch

Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

Lanfranchi, E., Pavkov-Keller, T., Koehler, E-M., Diepold, M., Steiner, K., Darnhofer, B., Hartler, J., Van Den Bergh, T., Joosten, H-J., Gruber-Khadjawi, M., Thallinger, G. G., Birner-Gruenberger, R., Gruber, K., Winkler, M. & Glieder, A., 10 May 2017, In : Scientific Reports. 7, 46738.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Erratum: Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

Lanfranchi, E., Pavkov-Keller, T., Koehler, E-M., Diepold, M., Steiner, K., Darnhofer, B., Hartler, J., Bergh, T. V. D., Joosten, H-J., Gruber-Khadjawi, M., Thallinger, G. G., Birner-Gruenberger, R., Gruber, K., Winkler, M. & Glieder, A., 26 May 2017, In : Scientific Reports. 7, 46834.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Expanding the CRISPR/Cas9 toolkit for Pichia pastoris with efficient donor integration and alternative resistance markers

Weninger, A., Fischer, J., Raschmanová, H., Kniely, C., Vogl, T. & Glieder, A., 1 Nov 2017, In : Journal of Cellular Biochemistry.

Research output: Contribution to journalArticleResearchpeer-review

Heme Enzymes for Biocatalysis

Glieder, A., 6 Oct 2017.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Pichia pastoris Alcohol Oxidase 1 (AOX1) Core Promoter Engineering by High Resolution Systematic Mutagenesis

Portela, R. M. C., Vogl, T., Ebner, K., Oliveira, R. & Glieder, A., 10 Nov 2017, In : Biotechnology Journal. 10.1002/biot.201700340.

Research output: Contribution to journalArticleResearchpeer-review

Protein expression: Yeast or E. coli

Glieder, A., 6 Oct 2017.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Substrate specificity of CYP505X from Aspergillus fumigatus

Bachler, T., Alkofer, A., Gralewska, P., Weninger, A., Glieder, A., Breinbauer, R. & Winkler, M., 11 Jul 2017.

Research output: Contribution to conferencePosterResearch

Synthetic Core Promoters as Universal Parts for Fine-Tuning Expression in Different Yeast Species

Portela, R. M. C., Vogl, T., Kniely, C., Fischer, J. E., Oliveira, R. & Glieder, A., 17 Mar 2017, In : ACS Synthetic Biology . 6, 3, p. 471-484 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

Access and use of fern hydroxynitrile lyase for biocatalysis

Glieder, A., Lanfranchi, E., Winkler, M., Gruber, K. & Pavkov-Keller, T., 28 Sep 2016.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

A new family of R-selective Hydroxynitrile lyases

Lanfranchi, E., Köhler, E-M., Diepold, M., Pavkov-Keller, T., Gruber, K., Steiner, K., Glieder, A. & Winkler, M., 11 Jul 2016.

Research output: Contribution to conferencePosterResearch

A new family of R-selective Hydroxynitrile lyases

Lanfranchi, E., Eva-Maria, K., Diepold, M., Pavkov-Keller, T., Gruber, K., Steiner, K., Glieder, A. & Winkler, M., 16 Nov 2016.

Research output: Contribution to conferencePosterResearch

A Toolbox of Diverse Promoters Related to Methanol Utilization: Functionally Verified Parts for Heterologous Pathway Expression in Pichia pastoris

Vogl, T., Sturmberger, L., Kickenweiz, T., Wasmayer, R., Schmid, C., Hatzl, A-M., Gerstmann, M. A., Pitzer, J., Wagner, M., Thallinger, G. G., Geier, M. & Glieder, A., 19 Feb 2016, In : ACS Synthetic Biology . 5, 2, p. 172-86 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Biotechnological advances towards an enhanced peroxidase production in Pichia pastoris

Krainer, F. W., Gerstmann, M. A., Darnhofer, B., Birner-Gruenberger, R. & Glieder, A., 10 Sep 2016, In : Journal of Biotechnology. 233, p. 181-9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Combinatorial optimization of CRISPR/Cas9 expression enables precision genome engineering in the methylotrophic yeast Pichia pastoris

Weninger, A., Hatzl, A-M., Schmid, C., Vogl, T. & Glieder, A., 10 Oct 2016, In : Journal of Biotechnology. 235, p. 139-49 11 p.

Research output: Contribution to journalArticleResearchpeer-review

COMPACT AND OPTIMIZED METABOLIC PATHWAY DESIGN IN PICHIA PASTORIS

Geier, M., Glieder, A. & Fauland, P., 6 May 2016, IPC No. C12N 15/ 09 A I, Patent No. WO2016066711, Priority date 28 Oct 2014, Priority No. EP20140190702

Research output: PatentResearch

Concurrent optimization strategies for high level protein production: Protein, strain and expression engineering

Weninger, A., Alkofer, A., Wimmer, R., Höppel, E., Eichmann, J. P-R., Schmid, C., Winkler, M. & Glieder, A., 22 Sep 2016.

Research output: Contribution to conferencePosterResearch

Expression of fungal cytochrome P450 variants in E. coli and their validation for API metabolite synthesis

Bachler, T., Eichmann, J. P-R., Weninger, A., Hammer, K., Tunjic, S., Glieder, A., Breinbauer, R. & Winkler, M., 12 Sep 2016.

Research output: Contribution to conferencePosterResearch

NEW HYDROXYNITRILE LYASES

Glieder, A., Lanfranchi, E., Steiner, K., Pavkov-Keller, T., Diepold, M. & Winkler, M., Feb 2016, Patent No. WO2016020528 (A1)

Research output: PatentResearch

Pichia pastoris mutants as host strains for efficient secretion of recombinant Branched Chain Aminotransferase (BCAT)

Weinhandl, K., Ballach, M., Winkler, M., Mudassar, A., Glieder, A., Birner-Gruenberger, R., Fotheringham, I. & Escalettes, F., 2016, In : Journal of Biotechnology. 235, p. 84-91 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Polypeptides having xylanase activity with a high conversion rate of xylose-containing polysaccharides

REISINGER, CHRISTOPH., Gamauf, C., KRAUS, MICHAEL., UNTERSTRASSER, ISABEL., MITROVIC, ALEKSANDRA. & Glieder, A., 9 Mar 2016, IPC No. C12N 9/ 24 A I, Patent No. EP2993230, Priority date 2 Sep 2014, Priority No. EP20140003017

Research output: PatentResearch

Recombinant production of a peroxidase-protein G fusion protein in Pichia pastoris

Krainer, F., Darnhofer, B., Birner-Gruenberger, R. & Glieder, A., 10 Feb 2016, In : Journal of Biotechnology. 219, p. 24-27 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Refined Pichia pastoris reference genome sequence

Sturmberger, L., Chappell, T., Geier, M., Krainer, F., Day, K. J., Vide, U., Trstenjak, S., Schiefer, A., Richardson, T., Soriaga, L., Darnhofer, B., Birner-Gruenberger, R., Glick, B. S., Tolstorukov, I., Cregg, J., Madden, K. & Glieder, A., 10 Oct 2016, In : Journal of Biotechnology. 235, p. 121-131 11 p.

Research output: Contribution to journalReview articleResearchpeer-review

Scent of bitter almond and a pinch of –omics: discovering a novel hydroxynitrile lyase

Lanfranchi, E., Pavkov-Keller, T., Steiner, K., Gruber, K., Winkler, M. & Glieder, A., 11 Oct 2016.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Synergism of proteomics and mRNA sequencing for enzyme discovery

Sturmberger, L., Wallace, P. W., Glieder, A. & Birner-Gruenberger, R., 10 Oct 2016, In : Journal of Biotechnology. 235, p. 132-8 7 p.

Research output: Contribution to journalArticleResearchpeer-review