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Author

  • Heidrun Gruber-Wölfler
2014

The Plug & Play Reactor: A Versatile Tool for Synthesis in Continuous Flow Mode

Gruber-Wölfler, H., Lichtenegger, G. J., Obermaier, K., Kitzler, H. & Khinast, J., 16 Jun 2014.

Research output: Contribution to conference(Old data) Lecture or Presentation

TiO2-Nanocoatings on Glass Surfaces to Reduce Alkali Ion Diffusion into Pharmaceutical Solutions

Gruber-Wölfler, H., Schweiger, S., Fraser, S. & Reichmann, A., 2014.

Research output: Contribution to conferencePoster

TiO2-Nanocoatings on Glass Surfaces to Reduce Alkali Ion Diffusion into Pharmaceutical Solutions

Gruber-Wölfler, H., Schweiger, S., Fraser, S. & Reichmann, A., 2014, In : Chemie - Ingenieur - Technik. 9, p. 1478-1479

Research output: Contribution to journalArticle

2015

Chemically Treatment of Glass Surfaces to Reduce Alkali Ion Diffusion into Aqueous Solutions

Gruber-Wölfler, H., Schweiger, S. & Neubauer, C., 21 Sep 2015.

Research output: Contribution to conference(Old data) Lecture or Presentation

Effective reaction rate in a fixed bed reactor

Gruber-Woelfler, H., Pichler, R. & Radl, S., 1 Jan 2015, Catalysis and Reaction Engineering Division 2015 - Core Programming Area at the 2015 AIChE Annual Meeting. American Institute of Chemical Engineers, p. 53-62 10 p. (Catalysis and Reaction Engineering Division 2015 - Core Programming Area at the 2015 AIChE Annual Meeting; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Effect of Particle Swelling on the Effective Reaction Rate in a Fixed Bed Reactor

Gruber-Wölfler, H., Pichler, R. & Radl, S., 8 Nov 2015.

Research output: Contribution to conference(Old data) Lecture or Presentation

Heterogeneous Catalysis in Continuous Flow: Plug and Play

Lichtenegger, G. J., Kitzler, H., Obermaier, K., Khinast, J. & Gruber-Wölfler, H., 11 Nov 2015.

Research output: Contribution to conference(Old data) Lecture or Presentation

Implementation of a UV/Vis System for the Inline Analytics of Heterogeneous Reactions in Continuous Flow Mode

Gruber-Wölfler, H., Turšič, V. & Lichtenegger, G. J., 14 Sep 2015.

Research output: Contribution to conference(Old data) Lecture or Presentation

Novel palladium substituted cerium-tin-oxides as highly active catalysts for continuous Suzuki-Miyaura reactions

Lichtenegger, G. J., Deshpande, P., Gruber-Wölfler, H. & Khinast, J., 2015.

Research output: Contribution to conferencePoster

Open Access
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Palladium Substituted Mixed Cerium-Tin-Oxides as Heterogeneous Catalysts for Continuous Suzuki Cross-Coupling Reactions

Lichtenegger, G. J., Deshpande, P. A., Gruber-Wölfler, H. & Khinast, J., 22 Sep 2015.

Research output: Contribution to conference(Old data) Lecture or Presentation

Strategies to develop leaching-free heterogeneous catalysts

Lichtenegger, G. J. & Gruber-Wölfler, H., 2015, In : Chimica Oggi. 33, 4, p. 12-19

Research output: Contribution to journalArticle

The Plug & Play Reactor: A Highly Flexible Device for Heterogeneous Reactions in Continuous Flow Mode

Gruber-Wölfler, H., Lichtenegger, G. J., Kitzler, H., Obermaier, K. & Khinast, J., 16 Jun 2015.

Research output: Contribution to conference(Old data) Lecture or Presentation

2016

Ce0.495Sn0.495Pd0.01O2 as highly stable and low-leaching catalyst in continuous Suzuki-Miyaura cross-coupling reactions

Lichtenegger, G. J., Khinast, J. & Gruber-Wölfler, H., 2016.

Research output: Contribution to conference(Old data) Lecture or Presentation

Development of an Integrated Continuous Crystallization Process of Vitamin D3

Escriba-Gelonch, M., Hessel, V., Noel, T. & Gruber-Wölfler, H., Sep 2016, Chemie Ingenieur Technik: Special Issue: ProcessNet-Jahrestagung und 32. DECHEMA-Jahrestagung der Biotechnologen 2016 . 9 ed. Vol. 88.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Development of an Integrated Continuous Crystallization Process of Vitamin D3

Escriba-Gelonch, M., Hessel, V., Noel, T. & Gruber-Wölfler, H., 14 Sep 2016.

Research output: Contribution to conference(Old data) Lecture or Presentation

Ionic Liquid Coated Transaminase for Biocatalysis in Organic Solvents

Grabner, B., Gundersen, M. T., Lois, S., Fantini, S., Gruber-Wölfler, H. & Woodley, J. M., 2016, (In preparation).

Research output: Contribution to conference(Old data) Lecture or Presentation

Mit ionischen Flüssigkeiten überzogene Transaminase für Biokatalyse in organischen Lösungsmitteln

Grabner, B., Gundersen, M. T., Lois, S., Fantini, S., Gruber-Wölfler, H. & Woodley, J. M., Sep 2016, Chemie Ingenieur Technik: Special Issue: ProcessNet-Jahrestagung 2016 und 32. DECHEMA-Jahrestagung der Biotechnolgie 2016. 9 ed. Wiley-VCH , Vol. 88. p. 1244

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mit ionischen Flüssigkeiten überzogene Transaminase für Biokatalyse in organischen Lösungsmitteln

Grabner, B., Gundersen, M. T., Lois, S., Fantini, S., Bartsch, S., Gruber-Wölfler, H. & Woodley, J. M., Sep 2016.

Research output: Contribution to conference(Old data) Lecture or Presentation

Printing medicines as orodispersible dosage forms: Effect of substrate on the printed micro-structure

Planchette, C., Pichler, H., Wimmer-Teubenbacher, M., Gruber, M., Gruber-Wölfler, H., Mohr, S., Tetyczka, C., Hsiao, W. K., Paudel, A., Roblegg, E. & Khinast, J., 2016, In : International Journal of Pharmaceutics. p. 518-527

Research output: Contribution to journalArticle

Suzuki-Miyaura coupling reactions using novel metal oxide supportedionic palladium catalysts

Lichtenegger, G. J., Maier, M. C., Hackl, M., Khinast, J., Gössler, W., Griesser, T., Phani Kumard, V. S., Gruber-Wölfler, H. & Deshpande, P. A., 1 Nov 2016, In : Journal of molecular catalysis / A. 426, p. 39-51

Research output: Contribution to journalArticle

The Plug & Play Reactor: A Highly Flexible Device for Heterogeneous Reactions in Continuous Flow

Lichtenegger, G. J., Turšič, V., Kitzler, H., Obermaier, K., Khinast, J. & Gruber-Wölfler, H., 27 Jul 2016, In : Chemie - Ingenieur - Technik. 88, 10

Research output: Contribution to journalArticle

2017

Catalytic cascade reactions for syntheses of sartans in continuous flow

Hiebler, K. & Gruber-Wölfler, H., 2017, (Accepted/In press).

Research output: Contribution to conferencePoster

Continuous Synthesis meets Purification: Handling Particles in Continuous Flow

Gruber-Wölfler, H., 14 Nov 2017.

Research output: Contribution to conference(Old data) Lecture or Presentation

DERA-catalyzed Statin Side-Chain Precursor Synthesis: Optimization using Design of Experiments

Grabner, B. & Gruber-Wölfler, H., Jul 2017.

Research output: Contribution to conferencePoster

Design and 3D printing of a stainless steel reactor for continuous difluoromethylations using fluoroform

Gutmann, B., Köckinger, M., Glotz, G., Ciaglia, T., Slama, E., Zadravec, M., Pfanner, S., Maier, M. C., Gruber-Wölfler, H. & Kappe, O., 20 Nov 2017.

Research output: Contribution to conference(Old data) Lecture or Presentation

Drug–Excipient Interactions in the Solid State: The Role of Different Stress Factors

Gressl, C., Brunsteiner, M., Davis, A., Landis, M., Pencheva, K., Scrivens, G., Sluggett, G. W., Wood, G. P. F., Gruber-Wölfler, H., Khinast, J. & Paudel, A., 2 Nov 2017, In : Molecular pharmaceutics. 14, 12, p. 4560-4571 11 p.

Research output: Contribution to journalArticle

Effect of Acetonitrile-Based Crystallization Conditions on the Crystal Quality of Vitamin D3

Gruber-Woelfler, H., Escribà-Gelonch, M., Noël, T., Maier, M. C. & Hessel, V., 1 Nov 2017, In : Chemical Engineering & Technology. 40, 11, p. 2016-2024 9 p.

Research output: Contribution to journalArticle

Heck Reaction using Pd-substituted Se-Sn-Oxides

Filzwieser, M., Grabner, B. & Gruber-Wölfler, H., Sep 2017.

Research output: Contribution to conferencePoster

Optimized process conditions for Deoxyribose-phosphate aldolase in chemical synthesis

Grabner, B. & Gruber-Wölfler, H., Sep 2017.

Research output: Contribution to conferencePoster

Pd-substituted mixed Ce-Sn-Oxides for Heck Reaction

Grabner, B., Filzwieser, M. & Gruber-Wölfler, H., Oct 2017.

Research output: Contribution to conference(Old data) Lecture or Presentation

Reaction Calorimetry in Microreactor Environments—Measuring Heat of Reaction by Isothermal Heat Flux Calorimetry

Glotz, G., Podmore, P., Knoechel, D. J., Gruber-Wölfler, H. & Kappe, C. O., 20 Apr 2017, In : Organic Process Research & Devlopment.

Research output: Contribution to journalArticle

Suzuki-Miyaura coupling reactions using novel metal oxide supported ionic palladium catalysts

Lichtenegger, G. J., Maier, M., Hackl, M., Khinast, J. G., Goessler, W., Griesser, T., Kumar, V. S. P., Gruber-Woelfler, H. & Deshpande, P. A., Jan 2017, In : Journal of molecular catalysis / A. 426, p. 39-51

Research output: Contribution to journalArticle

2018

Biocatalytic production of adiponitrile and related aliphatic linear α,ω-dinitriles

Betke, T., Maier, M. C., Gruber-Wölfler, H. & Gröger, H., 30 Nov 2018, In : Nature Communications . 9, p. 5112 9 p.

Research output: Contribution to journalArticle

Open Access

Continuous Aldol-Condensation by immobilized E.coli Cells

Grabner, B., Pokhilchuk, Y. & Gruber-Wölfler, H., Sep 2018.

Research output: Contribution to conferencePoster

Continuous-Flow In-Line Solvent-Swap Crystallization of Vitamin D3

Escriba-Gelonch, M., Hessel, V., Maier, M. C., Neira, M. F. & Gruber-Wölfler, H., 2018, In : Organic Process Research & Devlopment. 22, 2, p. 178-189

Research output: Contribution to journalArticle

Open Access

Crystal Shape Modification via Cycles of Growth and Dissolution in a Tubular Crystallizer

Neugebauer, P., Besenhard, M., Peter, A., Gruber-Wölfler, H. & Khinast, J., 15 Jun 2018, In : Crystal Growth and Design. 18, 8, p. 4403-4415

Research output: Contribution to journalArticle

Development and application of Pd-stabilized Pickering emulsions for catalytic cascade reactions in continuous flow

Hiebler, K., Gruber-Wölfler, H., Gonzales-Groom, R. & Binks, B. P., 2018.

Research output: Contribution to conferenceAbstract

Open Access

Development of Pd catalyzed Pickering Emulsions for Catalytic Cascade Reactions in Continuous Flow

Hiebler, K., Gruber-Wölfler, H., Binks, B. P. & Gonzales-Groom, R., 2018.

Research output: Contribution to conferenceAbstract

Heterogeneous Pd catalysts as emulsifiers in Pickering emulsions for integrated multistep synthesis in flow chemistry

Hiebler, K., Lichtenegger, G. J., Maier, M. C., Park, E. S., Gonzales-Groom, R., Binks, B. P. & Gruber-Wölfler, H., 18 Mar 2018, In : Beilstein Journal of Organic Chemistry . 14, p. 648 - 658

Research output: Contribution to journalArticle

Open Access

Room-temperature solid phase ionic liquid (RTSPIL) coated omega-transaminase: Development and application in orgranic solvents

Grabner, B., Nazario, Gundersen, M. T., Lois, S., Fantini, S., Bartsch, S., Woodley, J. M. & Gruber-Wölfler, H., Jun 2018, In : Molecular Catalysis. 452, p. 11-19

Research output: Contribution to journalArticle

2019

Combined Enzymatic Decarboxylation and Pd-catalyzed Heck Coupling in Continuous Flow

Grabner, B., Schweiger, A. K., Gavric, K., Kourist, R. & Gruber-Wölfler, H., Sep 2019.

Research output: Contribution to conferencePoster

From One-pot to One-flow: A chemo-enzymatic tandem reaction in continuous flow

Grabner, B., Schweiger, A. K., Gavric, K., Kourist, R. & Gruber-Wölfler, H., Sep 2019.

Research output: Contribution to conferencePoster

Multistep synthesis of a valsartan precursor in continuous flow

Hiebler, K., Soritz, S., Gavric, K., Birrer, S., Maier, M. C., Grabner, B. & Gruber-Woelfler, H., 1 Jan 2019, In : Journal of Flow Chemistry. 12 p.

Research output: Contribution to journalArticle

Open Access