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Author

  • Johannes Khinast

Calcium Stearate Micro-pellets: Impact of Drying Conditions on Pellet Dissolution

Schrank, S., Zimmer, A., Khinast, J. & Roblegg, E., 2011.

Research output: Contribution to conferencePosterResearch

2015

Accuracy of micro powder dosing via a vibratory sieve-chute system

Faulhammer, E., Besenhard, M., Paudel, A., Khinast, J., Llusa, M., Biserni, S., Calzolari, V. & Ferrari, A., 2015.

Research output: Contribution to conferencePosterResearch

Creating a Design Space for the scale up of a low-dose dosator capsule filling process for inhalation products

Faulhammer, E., Llusa, M., Khinast, J., Biserni, S. & Calzolari, V., 2015.

Research output: Contribution to conferencePosterResearch

2014

Optical coherence tomography data processing for in-line monitoring of a pharmaceutical film-coating process

Markl, D., Hannesschläger, G., Sacher, S., Buchsbaum, A. & Khinast, J., 2014, Proceedings of the 10th Minisymposium Verfahrenstechnik. ., p. 142-145

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

2018

Effect of particle shape in grinding mills using a GPU based DEM code

Khinast, J., Govender, N., Rajamani, R. K., Wilke, D. N., Wu, C-Y. & Glasser, B. J., 2018, In : Minerals engineering. p. 71-84

Research output: Contribution to journalArticleResearchpeer-review

2015

Accuracy of micro powder dosing via a vibratory sieve–chute system

Besenhard, M., Faulhammer, E., Fathollahi, S., Reif, G., Calzolari, V., Biserni, S., Lawrence, S., Llusa, M. & Khinast, J., 2015, In : European journal of pharmaceutics and biopharmaceutics. 94, p. 264-272

Research output: Contribution to journalArticleResearchpeer-review

2013

The effect of capsule-filling machine vibrations on average fill weight

Llusa, M., Faulhammer, E., Khinast, J., Lawrence, S., Biserni, S. & Calzolari, V., 2013, In : International Journal of Pharmaceutics. 454, 1, p. 381–387

Research output: Contribution to journalArticleResearchpeer-review

The Effect of Capsule-Filling Machine Vibrations on Average Fill Weight of Capsules

Faulhammer, E., Khinast, J., Llusa, M., Lawrence, S. M., Biserni, S. & Calzolari, V., 2013.

Research output: Contribution to conferencePosterResearch

2019

Deriving control parameter settings from process models to control capsule fillers integrated into continuous manufacturing

Wagner, B., Cheong, S. F., Brinz, T. & Khinast, J., 2 Sep 2019, In : Drug development and industrial pharmacy. 45, 9, p. 1523-1536

Research output: Contribution to journalArticleResearchpeer-review

2011

Investigation of tablet coating processes using Discrete Element Method simulations

Toschkoff, G., Suzzi, D. & Khinast, J., 30 Jun 2011.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

2018

COMBINATIONAL APPROACH FOR ADVANCED UNDERSTANDING OF A LOW-DOSE CAPSULE FILLING PROCESS FOR INHALATION APPLICATION

Faulhammer, E., Stranzinger, S., Calzolari, V., Biserni, S., Loidolt, P., Paudel, A. & Khinast, J., Apr 2018, In : Journal of Aerosol Medicine and Pulmonary Drug Delivery . 31, 2, p. A7-A7

Research output: Contribution to journalAbstractResearchpeer-review

2019

Particle-Level Residence Time Data in a Twin-Screw Feeder

Toson, P. & Khinast, J., 22 Oct 2019

Research output: Non-print formData set/DatabaseResearch

Open Access
2011

A deeper understanding of tablet coating processes through Discrete Element Method simulations

Toschkoff, G., Suzzi, D. & Khinast, J., 31 Mar 2011.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Stochastic Break-up Model for Euler-Lagrangian Simulations

Gruber, M. & Khinast, J., 2011.

Research output: Contribution to conferencePosterResearch

2013

Microstructure of Calcium Stearate Matrix Pellets: A Function of the Drying Process

Schrank, S., Kann, B., Windbergs, M., Glasser, B. J., Zimmer, A., Khinast, J. & Roblegg, E., 2013, In : Journal of Pharmaceutical Sciences . 102, 11, p. 3987-3997

Research output: Contribution to journalArticleResearchpeer-review

2014

Development of a drug abuse-alcohol-resistant formulation produced via hot-melt extrusion

Jedinger, N., Khinast, J. & Roblegg, E., 2014.

Research output: Contribution to conferencePosterResearch

2011

Calcium Stearate Pellets: Drying Induced Variations in Dosage Form Properties

Schrank, S., Zimmer, A., Glasser, B. J., Khinast, J. & Roblegg, E., 29 Sep 2011.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Calcium-Stearate Micro-pellets: Impact of Drying on Final Pellet Characteristics

Schrank, S., Reischl, D., Zimmer, A., Khinast, J. & Roblegg, E., 2011.

Research output: Contribution to conferencePosterResearch

Nanopartikel Herstellung durch Präzipitation: Prozessmodellierung und Reaktor-Scale-up

Eitzlmayr, A., Radl, S., Suzzi, D. & Khinast, J., 6 Oct 2011.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

2013

Calcium Stearate Matrix-Pellets: Impact of Drying on the Pellet Microstructure and the Ibuprofen Distribution Profiles

Schrank, S., Kann, B., Windbergs, M., Glasser, B. J., Zimmer, A., Khinast, J. & Roblegg, E., 3 Nov 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

2014

Real-time data processing for in-line monitoring of a pharmaceutical coating process by optical coherence tomography

Markl, D., Ziegler, J., Hannesschläger, G., Sacher, S., Buchsbaum, A., Leitner, M. & Khinast, J., 2014, Biophotonics: Photonic Solutions for Better Health Care IV. ., Vol. 9129. p. 1-12 (Proceeding of SPIE).

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

2012

Fluid Bed in a Flash

Scheibelhofer, O., Hohl, R., Salar-Behzadi, S., Haack, D., Koch, K., Sacher, S., Menezes, J. C. & Khinast, J., 28 Oct 2012.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

2013

Optical Coherence Tomography for non-destructive Tablet Coating Characterization

Markl, D., Hannesschläger, G., Leitner, M., Sacher, S. & Khinast, J., 13 Feb 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

2011

DEM simulation and pPIV analysis of wet powder blending in a four-bladed mixer

Radeke, C., Radl, S., Suzzi, D. & Khinast, J., 25 Sep 2011.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

2014

Multi-species multi-phase simulation of medium sized bioreactor with les using Lattice-Boltzmann Equations

Prakash, A., Witz, C., Radl, S. & Khinast, J., 2014, Engineering Sciences and Fundamentals 2014 - Core Programming Area at the 2014 AIChE Annual Meeting. American Institute of Chemical Engineers, Vol. 2. p. 984-986 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

2012

Ibuprofen-loaded Calcium Stearate Pellets: Pellet Characteristics in Dependence upond the Drying Conditions

Schrank, S., Glasser, B. J., Zimmer, A., Khinast, J. & Roblegg, E., 2012.

Research output: Contribution to conferencePosterResearch

Optimization of processing by characterizing critical protein powder parameters

Wahl, V., Piller, M., Leitgeb, S. & Khinast, J., 2012.

Research output: Contribution to conferencePosterResearch

2015

Co-Rotating Twin-Screw Extruders: Detailed Analysis of Conveying Elements Based on Smoothed Particle Hydrodynamics. Part 2: Mixing

Eitzlmayr, A. & Khinast, J., 2015, In : Chemical Engineering Science. 134, p. 880-886

Research output: Contribution to journalArticleResearchpeer-review

2011

Effect of blade angle and particle size on powder mixing performance in a rectangular box

Siraj, M. S., Radl, S., Glasser, B. J. & Khinast, J., 2011, In : Powder Technology. 211, p. 100-113

Research output: Contribution to journalArticleResearchpeer-review

2013

Strategy of Assessing Continuous Manufacturing Feasibility Based on Process and Materials Knowledge

Hohl, R. & Khinast, J., 4 Mar 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

2015

Carrier-based Dry Powder Inhalation Part I: Impact of Carrier Modification on Capsule Filling Processability and in vitro Aerodynamic Performance

Zellnitz, S., Faulhammer, E., Wahl, V., Paudel, A. & Khinast, J., 2015, (Accepted/In press) Drug Delivery to the Lungs - DDL26 - Book of abstracts. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Physical and chemical stability of different polymorphs of pharmaceutical solids

Gressl, C., Brunsteiner, M., Paudel, A., Khinast, J., Davis, A., Landis, M., Pencheva, K., Scrivens, G., Sluggett, G. & Wood, G., 16 Sep 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

2012

Scale-up of Capsule Filling Operations Using a Nozzle-Dosator Machine

Llusa, M., Faulhammer, E., Khinast, J., Scharrer, G., Lawrence, S., Biserni, S. & Calzolari, V., 2012, (Accepted/In press) Scale-up of Capsule Filling Operations Using a Nozzle-Dosator Machine. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

2014

Near infrared light spectroscopy: Applicability and new developments

Scheibelhofer, O., Sacher, S. & Khinast, J., 2014, In : European pharmaceutical review. 19, 1, p. 51-55

Research output: Contribution to journalArticleResearch

Nano-extrusion: A promising tool for continuous manufacturing of solid nano-formulations

Baumgartner, R., Eitzlmayr, A., Matsko, N., Tetyczka, C., Khinast, J. & Roblegg, E., 2014, In : International Journal of Pharmaceutics. 477, 1-2, p. 1-11

Research output: Contribution to journalArticleResearchpeer-review

2016

Dynamic cross-flow filtration: enhanced continuous small-scale solid-liquid separation

Gursch, J., Hohl, R., Dujmovic, D., Brozio, J., Krumme, M., Rasenack, N. & Khinast, J., 2016, In : Drug development and industrial pharmacy. 42, 6, p. 977-984

Research output: Contribution to journalArticleResearchpeer-review

2011

Industrial PAT Use Cases

Wahl, P., Scheibelhofer, O., Koller, D. M., Straka, G., Reiter, F., Schlingmann, M. & Khinast, J. G., 2011.

Research output: Contribution to conferencePosterResearch

2014

100% Monitoring of Manufactured Tablets with NIR Chemical Imaging

Wahl, P., Scheibelhofer, O., Sacher, S., Kerschhaggl, P. & Khinast, J., 2014.

Research output: Contribution to conferencePosterResearch

2013

Coalescence and Break-Up in Bubble Columns: Euler-Lagrange Simulations Using a Stochastic Approach

Gruber, M., Radl, S. & Khinast, J., 2013, In : Chemie - Ingenieur - Technik. 85, 7, p. 1118-1130

Research output: Contribution to journalArticleResearchpeer-review

2015

The Use of SAXS for Predicting Dissolution Rates of Lyophilized Fibrinogen

Wahl, V., Saurugger, E-M., Khinast, J. & Laggner, P., 2015.

Research output: Contribution to conferencePosterResearch

2011

Application of Process Analytical Technology (PAT) in Pharmaceutical Production

Wahl, P., Scheibelhofer, O., Koller, D. M. & Khinast, J., 2011.

Research output: Contribution to conferencePosterResearch

2015

Detailed Understanding of the Blending of Wet Powders and the Liquid Distribution Therein

Wu, M., Mohan, B., Khinast, J. & Radl, S., 17 Mar 2015, ProcessNet, Vortragsprogramm Grenzflächenbestimmte Systeme und Prozesse, Magdeburg,2015. Magdeburg

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

2018

Rapid automated process development of a continuous capsule-filling process

Wagner, B., Brinz, T., Otterbach, S. & Khinast, J., 30 Jul 2018, In : International Journal of Pharmaceutics. 546, 1-2, p. 154-165 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

Total Surveillance! Inline Monitoring of Tablets via NIR Chemical Imaging

Wahl, P., Scheibelhofer, O., Sacher, S. & Khinast, J., 25 Jan 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

2016

Light in Powder - Penetration and Information

Scheibelhofer, O., Wahl, P., Larchevêque, B. & Khinast, J., 21 Mar 2016.

Research output: Contribution to conferencePosterResearch

2017

Mechansitic modeling of a capsule filling process

Loidolt, P., Madlmeir, S. & Khinast, J., 30 Oct 2017, In : International Journal of Pharmaceutics.

Research output: Contribution to journalArticleResearchpeer-review

2014

The effects of powder compressibility, speed of capsule filling and pre-compression on plug densification

Llusa, M., Faulhammer, E., Khinast, J., Lawrence, S., Calzolari, V. & Biserni, S., 2014, In : International Journal of Pharmaceutics. 471, 1-2, p. 182-188

Research output: Contribution to journalArticleResearchpeer-review