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2015

Accuracy of Micro Powder Dosing and Feeding via a Vibratory Sieve-Chute System

Faulhammer, E., Paudel, A., Llusa, M., Besenhard, M. & Khinast, J., 8 Dec 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Accuracy of micro powder dosing via a vibratory sieve-chute system

Faulhammer, E., Besenhard, M., Paudel, A., Khinast, J., Llusa, M., Biserni, S., Calzolari, V. & Ferrari, A., 2015.

Research output: Contribution to conferencePosterResearch

Accuracy of micro powder dosing via a vibratory sieve–chute system

Besenhard, M., Faulhammer, E., Fathollahi, S., Reif, G., Calzolari, V., Biserni, S., Lawrence, S., Llusa, M. & Khinast, J., 2015, In : European journal of pharmaceutics and biopharmaceutics. 94, p. 264-272

Research output: Contribution to journalArticleResearchpeer-review

Advanced in silico modelling of the performance of inhalation products

Salar-Behzadi, S., Wu, S., Claudia, M., Stranzinger, S., Mercuri, A., Mohr, S., Bresciani, M., Khinast, J. & Eleonore, F., 2015.

Research output: Contribution to conferencePosterResearch

Alcohol dose dumping: The influence of ethanol on hot-melt extruded pellets comprising solid lipids

Jedinger, N., Schrank, S., Mohr, S., Feichtinger, A., Khinast, J. & Roblegg, E., 2015, In : European journal of pharmaceutics and biopharmaceutics. 92, p. 83-95

Research output: Contribution to journalArticleResearchpeer-review

Amorphous Solid Dispersion of Poorly Soluble API By Hot Melt Extrusion (HME) and Spray Drying (SD): A Rational Screening Approach

Paudel, A., Mercuri, A., Mohr, S., Bresciani, M. & Khinast, J., 8 Nov 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Bioreactor Simulation with CUDA

Witz, C. & Khinast, J., 2015, 7th International Berlin Workshop - IBW7 on Transport Phenomena with Moving Boundaries and More 30th-31st October 2014. p. 91-105 (Fortschritt-Berichte VDI Reihe 3 Verfahrenstechnik; no. 947).

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Calibration-free in-line monitoring of pellet coating processes via optical coherence tomography

Markl, D., Zettl, M., Hannesschläger, G., Sacher, S., Leitner, M., Buchsbaum, A. & Khinast, J., 2015, In : Chemical Engineering Science. 125, p. 200-208

Research output: Contribution to journalArticleResearchpeer-review

Lactose
Powders
Inhalation
Capsules
Mannitol

Carrier-based Dry Powder Inhalation Part I: Impact of Carrier Modification on Capsule Filling Processability and in vitro Aerodynamic Performance

Zellnitz, S., Faulhammer, E., Wahl, V., Paudel, A. & Khinast, J., 2015, (Accepted/In press) Drug Delivery to the Lungs - DDL26 - Book of abstracts. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Carrier-based Dry Powder Inhalation Part II: Impact of carrier material and API processing on the inter-particulate surface interactions in adhesive mixtures for inhalation

Zellnitz, S., Faulhammer, E., Wahl, V., Khinast, J. & Paudel, A., 2015, (Accepted/In press) Drug Delivery to the Lungs - DDL26 - Book of abstracts. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Continuous Crystallization of Proteins in a Tubular Plug-Flow Crystallizer

Neugebauer, P. & Khinast, J., 2015, In : Crystal growth & design. 15, p. 1089-1095

Research output: Contribution to journalArticleResearchpeer-review

Continuous Drying of Small Particles for Pharmaceutical Applications – An Evaluation of Selected Labscale Systems

Gursch, J., Hohl, R., Armenante, M., Dujmovic, D., van der Wel, P., Brozio, J., Krumme, M., Rasenack, N. & Khinast, J., 2015, In : Organic process research & development. 19, 12, p. 2055-2066

Research output: Contribution to journalArticleResearchpeer-review

Continuous Processing of API Suspensions via Dynamic Cross-flow Filtration

Gursch, J., Hohl, R., Toschkoff, G., Dujmovic, D., Brozio, J., Krumme, M., Rasenack, N. & Khinast, J., 2015, In : Journal of Pharmaceutical Sciences . 104, 10, p. 3481-3489

Research output: Contribution to journalArticleResearchpeer-review

Co-Rotating Twin-Screw Extruders: Detailed Analysis of Conveying Elements Based on Smoothed Particle Hydrodynamics. Part 1: Hydrodynamics

Eitzlmayr, A. & Khinast, J., 2015, In : Chemical Engineering Science. 134, p. 861-879

Research output: Contribution to journalArticleResearchpeer-review

Co-Rotating Twin-Screw Extruders: Detailed Analysis of Conveying Elements Based on Smoothed Particle Hydrodynamics. Part 2: Mixing

Eitzlmayr, A. & Khinast, J., 2015, In : Chemical Engineering Science. 134, p. 880-886

Research output: Contribution to journalArticleResearchpeer-review

Creating a Design Space for the scale up of a low-dose dosator capsule filling process for inhalation products

Faulhammer, E., Llusa, M., Khinast, J., Biserni, S. & Calzolari, V., 2015.

Research output: Contribution to conferencePosterResearch

Crystal Size Control in a Continuous Tubular Crystallizer

Besenhard, M., Neugebauer, P., Ho, C-D. & Khinast, J., 2015, In : Crystal growth & design. 15, p. 1683-1691

Research output: Contribution to journalArticleResearchpeer-review

Designed Blending for Near Infrared Calibration

Scheibelhofer, O., Grabner, B., Bondi, R. W. J., Igne, B., Sacher, S. & Khinast, J., 2015, In : Journal of Pharmaceutical Sciences . 7, 104, p. 2312-2322

Research output: Contribution to journalArticleResearchpeer-review

Detailed Simulation of Particle and Liquid Distribution in the Mixing Zone of a Twin-Screw Granulator

Kumar, A., Radl, S., Khinast, J., Gernaey, K. V., De Beer, T. & Nopens, I., 8 Nov 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Detailed Simulation of Particle and Liquid Distribution in the Mixing Zone of a Twin-Screw Granulator

Kumar, A., Radl, S., Khinast, J., Gernaey, K. V., De Beer, T. & Nopens, I., 8 Nov 2015.

Research output: Contribution to conferencePaperResearchpeer-review

Open Access
File

Detailed Understanding of the Blending of Wet Powders and the Liquid Distribution Therein

Wu, M., Mohan, B., Khinast, J. & Radl, S., 17 Mar 2015, ProcessNet, Vortragsprogramm Grenzflächenbestimmte Systeme und Prozesse, Magdeburg,2015. Magdeburg

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Powders
Liquids
Granulation
Direct numerical simulation
Finite difference method

Detailed Understanding of the Blending of Wet Powders and the Liquid Distribution Therein

Wu, M., Mohan, B., Khinast, J. & Radl, S., 16 Mar 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Development of Immediate-Release Tablets Processed via Hot-Melt Extrusion

Hörmann, T., Laske, S., Koscher, G. & Khinast, J., 23 Sep 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearchpeer-review

Evaluation of Parameter Estimation Methods for Crystallization Processes Modeled via Population Balance Equations

Besenhard, M., Chaudhury, A., Vetter, T., Ramachandran, R. & Khinast, J., 2015, In : Chemical Engineering Research and Design / A. 94, p. 275-289

Research output: Contribution to journalArticleResearchpeer-review

Evaluation of the surface free energy of inhalable powders

Pinto, J., Zellnitz, S., Bresciani, M., Khinast, J., Roblegg, E. & Paudel, A., 2015.

Research output: Contribution to conferencePosterResearch

Extractables and Leachables from Filter Material and their Effect on Human Granulocyte Colony-Stimulating Factor (hG-CSF)

Wahl, V., Mohr, S., Wieser, J., Khinast, J. & Paudel, A., 11 Nov 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

EXTRACTABLES AND LEACHABLES FROM FILTER MATERIAL AND THEIR IMPACT ON PROTEIN FORMULATION

Wahl, V., Wieser, J., Mohr, S., Khinast, J. & Paudel, A., 2015, Programme & Abstracts. Ghent: ., p. 114-115

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Flowsheet Modelling as a Tool for Plant-wide Control Strategy Development for Continuous Processes

Kruisz, J., Rehrl, J., Gruber, A. F., Sacher, S. & Khinast, J., 18 May 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Heterogeneous Catalysis in Continuous Flow: Plug and Play

Lichtenegger, G. J., Kitzler, H., Obermaier, K., Khinast, J. & Gruber-Wölfler, H., 11 Nov 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

In-line Monitoring of Segregation Effects in a Pharmaceutical Tableting Process

Sacher, S., Wahl, P., Scheibelhofer, O., Hohl, R. & Khinast, J., 25 Jan 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

IPPE-TU Graz: green engineering inside and beyond the borders of process technology

Gruber-Wölfler, H., Schnitzer, H., Narodoslawsky, M. & Khinast, J., 2015, In : Green processing and synthesis. 4, 1, p. 51-54

Research output: Contribution to journalArticleResearchpeer-review

Micro-Pelletizing of Pharmaceutical HME Formulations Using a Die Face Pelletizer

Witschnigg, A., Koscher, G., Treffer, D. F., Mürb, R., Laske, S. & Khinast, J., 2015, (Accepted/In press) Polymer Processing Society 2015. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Moisture induced changes in secondary structure and crystallinity of human fibrinogen powders

Wahl, V., Scheibelhofer, O., Rößl, U., Leitgeb, S., deBeer, T. & Khinast, J., 2015, Abstracts Poster. Vienna: ., p. 186-187

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Monitoring of a Hot Melt Coating Process

Scheibelhofer, O., Hohl, R., Salar-Behzadi, S., Haack, D., Koch, K., Kerschhaggl, P., Lochmann, D., Sacher, S. & Khinast, J., 2015.

Research output: Contribution to conferencePosterResearch

Multi-methodological investigation on the variability in the microstructure of HPMC capsules

Faulhammer, E., Wahl, V., Markl, D., Khinast, J., Paudel, A. & Lawrence, S., 2015.

Research output: Contribution to conferencePosterResearch

Novel palladium substituted cerium-tin-oxides as highly active catalysts for continuous Suzuki-Miyaura reactions

Lichtenegger, G. J., Deshpande, P., Gruber-Wölfler, H. & Khinast, J., 2015.

Research output: Contribution to conferencePosterResearch

Open Access
File

Palladium Substituted Mixed Cerium-Tin-Oxides as Heterogeneous Catalysts for Continuous Suzuki Cross-Coupling Reactions

Lichtenegger, G. J., Deshpande, P. A., Gruber-Wölfler, H. & Khinast, J., 22 Sep 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Physical and chemical stability of different polymorphs of pharmaceutical solids

Gressl, C., Brunsteiner, M., Paudel, A., Khinast, J., Davis, A., Landis, M., Pencheva, K., Scrivens, G., Sluggett, G. & Wood, G., 16 Sep 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Prozessentwicklung zur Herstellung schmelzextrudierter pharmazeutischer Produkte

Treffer, D. F., Hörmann, T., Koscher, G. & Khinast, J., 3 Dec 2015, Konferenzband: 41. Deutsche Compoundiertagung - Prozessoptimierung an Compoundieranlagen. Nürnberg

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

QbD based model development for continuous pharmaceutical manufacturing

Kruisz, J., Rehrl, J., Gruber, A. F. & Khinast, J., 2015.

Research output: Contribution to conferencePosterResearch

Open Access
File

Retention-time prediction for polycyclic aromatic compounds in reversed-phase capillary electro-chromatography.

Feenstra, P., Gruber-Wölfler, H., Brunsteiner, M. & Khinast, J., 2015, In : Journal of molecular modeling. 21, p. 124-133

Research output: Contribution to journalArticleResearchpeer-review

Rigorous Modeling of CO2 Absorption and Chemisorption: The Influence of Bubble Coalescence and Breakage

Gruber, M., Radl, S. & Khinast, J., 2015, In : Chemical Engineering Science. 137, p. 188-204

Research output: Contribution to journalArticleResearchpeer-review

Scale-Up of Pharmaceutical Hot Melt Extruders Supported by 3D Smoothed Particle Hydrodynamics and 1D Predictive Modelling

Matic, J., Eitzlmayr, A. & Khinast, J., 9 Nov 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Technology of Filling Low Dosage Inhalation Powders with a Dosator Nozzle Into Capsules

Faulhammer, E., Khinast, J. & Llusa, M., 7 Oct 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch