Research output per year
Research output per year
Project Details
Description
The component aims at identifying the subset of glycerophospholipid hydrolases in mammalian cell proteomes. For this purpose taylor-made phospholipids will be developed as suicide inhibitors, photoactivatable probes and substrates for the selective detection and functional characterization of the active target enzymes in cultured animal cells and tissues. These novel molecular tools will be used to identify yet unknown phospholipases that escaped detection by conventional methods so far.
| Status | Finished |
|---|---|
| Effective start/end date | 1/02/09 → 31/01/12 |
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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Adipose triglyceride lipase (ATGL) and hormone sensitive lipase (HSL) deficiences affect expression of lipolytic activities in mouse adipose tissues
Morak, M., Schmidinger, H., Riesenhuber, G., Rechberger G, N. V., Kollroser M, N. V., Haemmerle, G., Zechner, R., Kronenberg, F. & Hermetter, A., 2012, In: Molecular & Cellular Proteomics. 11, 12, p. 1777-1789Research output: Contribution to journal › Article › peer-review
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Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) deficiencies affect expression of lipolytic activities in mouse adipose tissues
Morak, M., Schmidinger, H., Riesenhuber, G., Rechberger GN, N. V., Kollroser M, N. V., Haemmerle G, N. V., Zechner R, N. V., Kronenberg F, N. V. & Hermetter, A., 2012, In: Molecular & Cellular Proteomics. 11, 12, p. 1777-1789Research output: Contribution to journal › Article › peer-review
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Catalytic residues and a predicted structure of tetrahydrobiopterin-dependent alkylglcerol monooxygenase
Watschinger, K., Fuchs, JE., Yarov-Yarovoy, V., Keller, MA., Golderer, G., Hermetter, A., Werner-Felmayer, G., Hulo, N. & Werner, ER., 2012, In: Biochemical Journal. 443, 1, p. 279-286Research output: Contribution to journal › Article › peer-review