Effects of Troglitazone on Lipid Metabolism in Obese Zucker Rats

      Project: Research project

      Project Details


      To identify mechanism(s) by which Troglitazone improves insulin resistance we will study the effects of Troglitazone on lipid metabolism in obese Zucker rats. Our specific goals are: 1) is to assess lipolysis during euglycemic conditions in lean and obese Zucker rats and obese Zucker rats treated with Troglitazone; and 2) to estimate glucose turnover rates in obese Zucker rats treated with Troglitazone during euglycemic conditions and elevated FFA levels.
      Effective start/end date1/03/9931/12/02