Effects of Troglitazone on Lipid Metabolism in Obese Zucker Rats

      Project: Research project

      Description

      To identify mechanism(s) by which Troglitazone improves insulin resistance we will study the effects of Troglitazone on lipid metabolism in obese Zucker rats. Our specific goals are: 1) is to assess lipolysis during euglycemic conditions in lean and obese Zucker rats and obese Zucker rats treated with Troglitazone; and 2) to estimate glucose turnover rates in obese Zucker rats treated with Troglitazone during euglycemic conditions and elevated FFA levels.
      StatusFinished
      Effective start/end date1/03/9931/12/02