1995 …2021
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Research Output 1995 2019

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Poster
2019

Capsaicin Metabolite Synthesis by Fungal Cytochrome P450

Willim, M., Bachler, T., Schweda, B., Migglautsch, A. K., Glieder, A., Breinbauer, R. & Winkler, M., 14 Feb 2019.

Research output: Contribution to conferencePosterResearch

Iodonium-based Probes for the Activity-based Protein Profiling of Oxidoreductases

Kljajic, M., Darnhofer, B., Schittmayer, M., Kollau, A., Mayer, B., Birner-Grünberger, R. & Breinbauer, R., 28 Mar 2019.

Research output: Contribution to conferencePosterResearchpeer-review

2018

Development of Small-Molecule Inhibitors of Adipose Triglyceride Lipase (ATGL)

Migglautsch, A. K., Doler, C. J., Schweiger, M., Mayer, N., Fuchs, E., Grabner, G., Romauch, M., Zechner, R., Zimmermann, R. & Breinbauer, R., 6 Sep 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Palladium-Mediated Allylation of Cysteine for Site-Selective Bioconjugation

Schlatzer, T., Kriegesmann, J., Becker, C. F. W. & Breinbauer, R., 13 Dec 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Palladium-Mediated Allylation of Cysteine for Site-Selective Bioconjugation

Schlatzer, T., Kriegesmann, J., Becker, C. F. W. & Breinbauer, R., 18 Sep 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Palladium-Mediated Allylation of Cysteine for Site-Selective Bioconjugation of Peptides and Proteins

Schlatzer, T., Kriegesmann, J., Schröder, H., Trobe, M., Becker, C. F. W. & Breinbauer, R., 29 Aug 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Pd-Mediated Allylation of Cysteine for Site-Selective Bioconjugation of Peptides and Proteins

Schlatzer, T., Kriegesmann, J., Schröder, H., Trobe, M., Lembacher-Fadum, C., Becker, C. F. W. & Breinbauer, R., 10 Sep 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Synthesis and Biological Characterization of Teraryl-based alpha-Helix-Mimetics

Blesl, J., Vareka, M., Trobe, M. & Breinbauer, R., 26 Jun 2018.

Research output: Contribution to conferencePosterResearch

Total Syntheses of Tilivalline and Tilimycin, Cytotoxic Secondary Metabolites of Klebsiella Oxytoca

Lembacher-Fadum, C., Dornisch, E., Pletz, J., Glabonjat, R. A., Martin, F., Neger, M., Högenauer, C., Francesconi, K. A., Kroutil, W., Zangger, K., Zechner, E. L. & Breinbauer, R., 27 Aug 2018.

Research output: Contribution to conferencePosterResearchpeer-review

2017

A General and Direct Reductive Amination of Aldehydes and Ketones with Electron-Deficient Anilines

Berg, B., Pletz, J. & Breinbauer, R., 3 Sep 2017.

Research output: Contribution to conferencePosterResearch

Chemoenzymatic Synthesis of α-Quaternary Stereogenic α-Amino Acids

Blesl, J., Strohmeier, G., Fesko, K. & Breinbauer, R., 25 Sep 2017.

Research output: Contribution to conferencePosterResearch

Chemoenzymatic Synthesis of α-Quaternary Stereogenic α-Amino Acids

Blesl, J., Strohmeier, G., Fesko, K. & Breinbauer, R., 30 Aug 2017.

Research output: Contribution to conferencePosterResearch

Development of small-molecule inhibitors of Adipose Triglyceride Lipase (ATGL)

Migglautsch, A. K., Doler, C. J., Schweiger, M., Mayer, N., Fuchs, E., Grabner, G., Romauch, M., Zechner, R., Zimmermann, R. & Breinbauer, R., 25 Sep 2017.

Research output: Contribution to conferencePosterResearch

Investigation of an Unexpected Cyclization During a Horner-Wadsworth-Emmons Reaction

Lembacher-Fadum, C., Ivkovic, J., Pletz, J., Ratzenböck, K., Maringer, M., Weber, H., Fischer, R. & Breinbauer, R., 5 Sep 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Kinetic studies of inhibition of hDPP3 by hydroxyethylene transition state peptidomimetics

Jha, S., Ivkovic, J., Kumar, P., Taschler, U., Zimmermann, R., Gruber, K., Breinbauer, R. & Macheroux, P., 3 Feb 2017.

Research output: Contribution to conferencePosterResearch

New Palladium Catalyzed Approach towards 5-membered Nitrogen-containing Heterocycles

Kljajic, M. & Breinbauer, R., 22 Jul 2017.

Research output: Contribution to conferencePosterResearch

New “old yellow enzyme”: a reductive C-C bond formation using engineered enoate reductase

Heckenbichler, K., Schweiger, A. K., Gruber, K., Macheroux, P. & Breinbauer, R., 9 Jul 2017.

Research output: Contribution to conferencePosterResearch

Peptidomimetic transition state inhibitors as chemical probes to explore in-vivo role of dipeptidyl peptidase 3

Jha, S., Ivkovic, J., Kumar, P., Taschler, U., Zimmermann, R., Gruber, K., Breinbauer, R. & Macheroux, P., Jul 2017.

Research output: Contribution to conferencePosterResearch

Pharmacological Inhibition of Adipose Triglyceride Lipase corrects High-Fat Diet-Induced Insulin Resistance and Hepatosteatosis in mice

Breinbauer, R., Doler, C. J., Schweiger, M., Migglautsch, A. K., Mayer, N., Grabner, G., Zechner, R. & Zimmermann, R., 13 Sep 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Pharmacological inhibition of ATGL (Adipose Triglyceride Lipase) corrects high-fat diet-induced hepatosteatosis in mice

Schweiger, M., Mayer, N., Romauch, M., Grabner, G., Doler, C. J., Migglautsch, A. K., Hütter, S., Kotzbeck, P., Eichmann, T. O., Yamada, S., Knittelfelder, O., Diwoky, C., Lass, A., Zechner, R., Zimmermann, R. & Breinbauer, R., 27 Jun 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Post-Translational Pd-Catalyzed S-Prenylation of Peptides and Proteins

Schlatzer, T., Schröder, H., Trobe, M., Lembacher-Fadum, C., Becker, C. & Breinbauer, R., 28 Sep 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones

Strandback, E. S., Lienhart, W-D., Hromic-Jahjefendic, A., Högler, A., Winkler, A., Zangger, K., Dandachi, N., Heitzer, E., Bourgeois, B., Madl, T., Breinbauer, R., Gruber, K. & Macheroux, P., 2017.

Research output: Contribution to conferencePosterResearch

Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones

Strandback, E. S., Lienhart, W-D., Hromic-Jahjefendic, A., Högler, A., Winkler, A., Zangger, K., Dandachi, N., Heitzer, E., Bourgeois, B., Madl, T., Breinbauer, R., Gruber, K. & Macheroux, P., 2017.

Research output: Contribution to conferencePosterResearch

Stabilization of a cancer associated variant of human NQO1 by the use of small-molecular chaperones

Strandback, E. S., Lienhart, W-D., Hromic-Jahjefendic, A., Högler, A., Waltenstorfer, D., Winkler, A., Zangger, K., Dandachi, N., Heitzer, E., Bourgeois, B., Madl, T., Breinbauer, R., Gruber, K. & Macheroux, P., 2017.

Research output: Contribution to conferencePosterResearch

Substrate specificity of CYP505X from Aspergillus fumigatus

Bachler, T., Alkofer, A., Gralewska, P., Weninger, A., Glieder, A., Breinbauer, R. & Winkler, M., 11 Jul 2017.

Research output: Contribution to conferencePosterResearch

Synthesis of an Amphiphilic Oligoaryl-based ApoA1 Mimetic

Dobrounig, P. S. & Breinbauer, R., 29 Jul 2017.

Research output: Contribution to conferencePosterResearchpeer-review

2016

A General and Direct Reductive Amination of Aldehydes and Ketones with Electron-Deficient Anilines

Pletz, J., Berg, B. & Breinbauer, R., 28 Jun 2016.

Research output: Contribution to conferencePosterResearch

A Modular Synthesis of an Amphiphilic Oligoaryl-based ApoA1 Mimetic as a Potential Drug Carrier

Dobrounig, P. S. & Breinbauer, R., 28 Jun 2016.

Research output: Contribution to conferencePosterResearchpeer-review

An Additive-Free Approach for the Alpha-Allylation of Nitrogen Heterocycles

Kljajic, M. & Breinbauer, R., 30 Jun 2016.

Research output: Contribution to conferencePosterResearch

Nitrogen
Activation
Pharmaceuticals
Rearrangement
Substrate

Characterization and therapeutic exploitation of human dipeptidyl peptidase III (hDPPIII): an enzyme with multifaceted functionality

Jha, S., Taschler, U., Ivkovic, J., Breinbauer, R., Gruber, K., Zimmermann, R. & Macheroux, P., Sep 2016.

Research output: Contribution to conferencePosterResearch

Development of small-molecule inhibitors targeting adipose triglyceride lipase (ATGL)

Doler, C. J., Migglautsch, A., Mayer, N., Fuchs, E., Schweiger, M., Romauch, M., Grabner, G., Zechner, R., Zimmermann, R. & Breinbauer, R., 28 Jun 2016, p. 1-1. 1 p.

Research output: Contribution to conferencePosterResearch

Lipase
Fatty Acids
White Adipose Tissue
Cachexia
Glucose Intolerance

Expression of fungal cytochrome P450 variants in E. coli and their validation for API metabolite synthesis

Bachler, T., Eichmann, J. P-R., Weninger, A., Hammer, K., Tunjic, S., Glieder, A., Breinbauer, R. & Winkler, M., 12 Sep 2016.

Research output: Contribution to conferencePosterResearch

Modular Synthesis of Teraryl-based alpha-Helix-Mimetics

Breinbauer, R., Trobe, M., Peters, M., Grimm, S. & Wölfl, B., 5 Sep 2016.

Research output: Contribution to conferencePosterResearch

Modular Synthesis of Teraryl-based alpha-Helix-Mimetics for the Inhibition of Protein-Protein-Interactions

Trobe, M., Peters, M., Grimm, S., Wölfl, B. & Breinbauer, R., 1 Sep 2016.

Research output: Contribution to conferencePosterResearch

New “old yellow enzyme”: Reductive C-C bond formation using an engineered enoate reductase

Heckenbichler, K., Schweiger, A. K., Binter, A., Macheroux, P., Gruber, K. & Breinbauer, R., 2016.

Research output: Contribution to conferencePosterResearch

Novel insights into structural destabilization of a cancer associated variant of human NQO1

Strandback, E. S., Lienhart, W-D., Hromic, A., Pletz, J., Köberl, C., Gudipati, V., Gruber, K., Breinbauer, R. & Macheroux, P., 2016.

Research output: Contribution to conferencePosterResearch

Targeting human dipeptidyl peptidase III (hDPPIII): a therapeutic potential for safer pain management

Jha, S., Ivkovic, J., Taschler, U., Kumar, P., Zimmermann, R., Gruber, K., Breinbauer, R. & Macheroux, P., Sep 2016.

Research output: Contribution to conferencePosterResearch

Towards API Metabolite Synthesis by Fungal Cytochrome P450 variants

Bachler, T., Eichmann, J. P-R., Weninger, A., Glieder, A., Breinbauer, R. & Winkler, M., 16 Nov 2016.

Research output: Contribution to conferencePosterResearch

Towards understanding the structural destabilization of a cancer associated variant of human NQO1

Strandback, E. S., Lienhart, W-D., Köberl, C., Hromic, A., Pletz, J., Gudipati, V., Gruber, K., Breinbauer, R. & Macheroux, P., 2016.

Research output: Contribution to conferencePosterResearch

2015

A Base- and Additive-Free Approach of the Tsuji-Trost Reaction for the Synthesis of N-Heterocycles

Kljajic, M. & Breinbauer, R., 2015.

Research output: Contribution to conferencePosterResearch

Open Access
File

A luciferous surprise: A new natural aldehyde substrate for bacterial bioluminescence

Tabib, C., Brodl, E., Bergner, T., Ivkovic, J., Wallner, S., Breinbauer, R. & Macheroux, P., 2015.

Research output: Contribution to conferencePosterResearch

A modular synthesis of teraryl-based alpha-helix mimetics for inhibition of protein-protein-interactions

Trobe, M., Peters, M., Grimm, S., Wölfl, B. & Breinbauer, R., 2015.

Research output: Contribution to conferencePosterResearch

A modular synthesis of teraryl-based α-helix mimetics for inhibition of protein-protein interactions

Trobe, M., Peters, M., Grimm, S., Wölfl, B. & Breinbauer, R., 2015.

Research output: Contribution to conferencePosterResearch

Characterization and therapeutic potential of DPP III knockout mice

Jha, S., Taschler, U., Ivkovic, J., Breinbauer, R., Zimmermann, R. & Macheroux, P., 3 Dec 2015.

Research output: Contribution to conferencePosterResearch

Design and Synthesis of Inhibitors of Dipeptidyl Peptidase-III

Lembacher-Fadum, C., Ivkovic, J., Jha, S., Kumar, P., Gruber, K., Macheroux, P. & Breinbauer, R., 2015.

Research output: Contribution to conferencePosterResearch

Design and Synthesis of Inhibitors of Dipeptidyl Peptidase-III

Lembacher-Fadum, C., Ivkovic, J., Jha, S., Kumar, P., Gruber, K., Macheroux, P. & Breinbauer, R., 3 Dec 2015.

Research output: Contribution to conferencePosterResearchpeer-review

Design and Synthesis of Inhibitors of DPP3

Ivkovic, J., Kumar, P., Gruber, K., Macheroux, P. & Breinbauer, R., 2015.

Research output: Contribution to conferencePosterResearch

Development of Inhibitors of PhzE - A New Target for Antibiotic Intervention

Guttenberger, N., Breinbauer, R. & Blankenfeldt, W., 2015.

Research output: Contribution to conferencePosterResearch

Discovery and Characterization of Atglistatin – The First Inhibitor of ATGL (Adipose Triglyzeride Lipase)

Mayer, N., Schweiger, M., Romauch, M., Ivkovic, J., Fuchs, E., Doler, C. J., Lass, A., Höfler, G., Zechner, R., Zimmermann, R. & Breinbauer, R., 2015.

Research output: Contribution to conferencePosterResearch

Iterative Suzuki-Coupling for the Synthesis of an Amphiphilic Oligoaryl-based ApoA1 Mimetic as a Potential Drug Carrier

Dobrounig, P. S. & Breinbauer, R., 2015.

Research output: Contribution to conferencePosterResearch