Peter Macheroux

Univ.-Prof. Dr.rer.nat.

1982 …2023
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Research Output 1982 2018

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Poster
2018

LuxF and its various roles in bacterial bioluminescence

Brodl, E., Horn, C., Niederhauser, J. & Macheroux, P., 2018.

Research output: Contribution to conferencePosterResearch

The monolignol oxidoreductase AtBBE-like protein 15: Characterization, rational engineering and biocatalytic applications.

Daniel, B., Messenlehner, J., Schrittwieser, J. H., Pils, S., Kroutil, W. & Macheroux, P., 28 Aug 2018.

Research output: Contribution to conferencePosterResearchpeer-review

2017

Application of hydratases for flavor and fragrance synthesis

Engleder, M., Pavkov-Keller, T., Emmerstorfer, A., Hromic, A., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Daniel, M., Schürmann, M., Wallner, S., Macheroux, P., Pichler, H. & Gruber, K., 14 Nov 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Application of hydratases for flavour and fragrance synthesis

Engleder, M., Pavkov-Keller, T., Emmerstorfer, A., Altijana, H., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Mink, D., Schürmann, M., Wallner, S., Macheroux, P., Gruber, K. & Pichler, H., 20 Sep 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Bacterial bioluminescence: the in vitro formation of myrFMN

Brodl, E., Tabib, C. & Macheroux, P., 3 Feb 2017.

Research output: Contribution to conferencePosterResearch

Genomic integration of luxF into the Vibrio harveyi lux operon

Brodl, E., Schild, S. & Macheroux, P., 2017.

Research output: Contribution to conferencePosterResearch

Kinetic studies of inhibition of hDPP3 by hydroxyethylene transition state peptidomimetics

Jha, S., Ivkovic, J., Kumar, P., Taschler, U., Zimmermann, R., Gruber, K., Breinbauer, R. & Macheroux, P., 3 Feb 2017.

Research output: Contribution to conferencePosterResearch

New “old yellow enzyme”: a reductive C-C bond formation using engineered enoate reductase

Heckenbichler, K., Schweiger, A. K., Gruber, K., Macheroux, P. & Breinbauer, R., 9 Jul 2017.

Research output: Contribution to conferencePosterResearch

Peptidomimetic transition state inhibitors as chemical probes to explore in-vivo role of dipeptidyl peptidase 3

Jha, S., Ivkovic, J., Kumar, P., Taschler, U., Zimmermann, R., Gruber, K., Breinbauer, R. & Macheroux, P., Jul 2017.

Research output: Contribution to conferencePosterResearch

Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones

Strandback, E. S., Lienhart, W-D., Hromic-Jahjefendic, A., Högler, A., Winkler, A., Zangger, K., Dandachi, N., Heitzer, E., Bourgeois, B., Madl, T., Breinbauer, R., Gruber, K. & Macheroux, P., 2017.

Research output: Contribution to conferencePosterResearch

Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones

Strandback, E. S., Lienhart, W-D., Hromic-Jahjefendic, A., Högler, A., Winkler, A., Zangger, K., Dandachi, N., Heitzer, E., Bourgeois, B., Madl, T., Breinbauer, R., Gruber, K. & Macheroux, P., 2017.

Research output: Contribution to conferencePosterResearch

Stabilization of a cancer associated variant of human NQO1 by the use of small-molecular chaperones

Strandback, E. S., Lienhart, W-D., Hromic-Jahjefendic, A., Högler, A., Waltenstorfer, D., Winkler, A., Zangger, K., Dandachi, N., Heitzer, E., Bourgeois, B., Madl, T., Breinbauer, R., Gruber, K. & Macheroux, P., 2017.

Research output: Contribution to conferencePosterResearch

Structure-based reaction mechanism of oleate hydratase from Elizabethkingia meningoseptica

Engleder, M., Pavkov-Keller, T., Emmerstorfer-Augustin, A., Hromic, A., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Daniel, M., Martin, S., Wallner, S., Macheroux, P., Gruber, K. & Pichler, H., 23 Apr 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Hydro-Lyases
Oleic Acid
Hydration
Flavin-Adenine Dinucleotide
Carbon

Studying the role of the only berberine bridge enzyme-like protein in Physcomitrella patens

Toplak, M., Ulicevic, J., Daniel, B., Wallner, S. & Macheroux, P., 3 Feb 2017.

Research output: Contribution to conferencePosterResearch

The origin of the berberine bridge enzyme-like protein family in plants

Toplak, M., Wiedemann, G., Ulicevic, J., Daniel, B., Hoernstein, S., Kothe, J., Reski, R., Winkler, A. & Macheroux, P., Jul 2017.

Research output: Contribution to conferencePosterResearch

2016

Berberine bridge enzyme-like proteins: From characterization to application

Daniel, B., Pils, S., Steiner, B., Wallner, S., Pavkov-Keller, T., Gruber, K., Schrittwieser, J., Fuchs, M., Kroutil, W. & Macheroux, P., 12 Sep 2016.

Research output: Contribution to conferencePosterResearch

Characterization and therapeutic exploitation of human dipeptidyl peptidase III (hDPPIII): an enzyme with multifaceted functionality

Jha, S., Taschler, U., Ivkovic, J., Breinbauer, R., Gruber, K., Zimmermann, R. & Macheroux, P., Sep 2016.

Research output: Contribution to conferencePosterResearch

EasC and EasE – what is their role in chanoclavine I formation?

Toplak, M., Wallner, S. & Macheroux, P., Feb 2016.

Research output: Contribution to conferencePosterResearch

Function of monolignol oxidoreductases from the berberine bridge enzyme-like protein family in Arabidopsis thaliana

Steiner, B., Daniel, B., Jammer, A., Wallner, S., Gruber, K., Pavkov, T., van der Graaff, E., Müller, M., Roitsch, T. & Macheroux, P., 2016.

Research output: Contribution to conferencePosterResearch

Investigation of the Reasons for the Destabilization of a Natural Variant of NAD(P)H:quinone oxidoreductase 1

Strandback, E. S., Lienhart, W-D., Gudipati, V. & Macheroux, P., 5 Feb 2016.

Research output: Contribution to conferencePosterResearch

In vitro bioluminescence: an enzyme cascade producing myrFMN

Brodl, E., Tabib, C. & Macheroux, P., 28 Aug 2016.

Research output: Contribution to conferencePosterResearch

Monolignol oxidoreductases from the berberine bridge enzyme-like protein family

Steiner, B., Daniel, B., Wallner, S., Gruber, K., Pavkov, T., van der Graaff, E., Roitsch, T. & Macheroux, P., 2016.

Research output: Contribution to conferencePosterResearch

New insights in bacterial bioluminescence: in vitro myrFMN production

Brodl, E., Tabib, C. & Macheroux, P., 7 Jul 2016.

Research output: Contribution to conferencePosterResearch

New “old yellow enzyme”: Reductive C-C bond formation using an engineered enoate reductase

Heckenbichler, K., Schweiger, A. K., Binter, A., Macheroux, P., Gruber, K. & Breinbauer, R., 2016.

Research output: Contribution to conferencePosterResearch

Novel insights into structural destabilization of a cancer associated variant of human NQO1

Strandback, E. S., Lienhart, W-D., Hromic, A., Pletz, J., Köberl, C., Gudipati, V., Gruber, K., Breinbauer, R. & Macheroux, P., 2016.

Research output: Contribution to conferencePosterResearch

PpBBE-studying the origine of BBE-like enzymes in plants

Toplak, M., Ulicevic, J., Daniel, B., Wallner, S. & Macheroux, P., 30 Sep 2016.

Research output: Contribution to conferencePosterResearch

PpBBE – the ancestor of berberine bridge enzyme-like enzymes in plants?

Toplak, M., Daniel, B., Wallner, S., Wiedemann, G., Reski, R. & Macheroux, P., Jul 2016.

Research output: Contribution to conferencePosterResearch

Structure-based reaction mechanism of oleate hydratase from Elizabethkingia meningoseptica

Engleder, M., Pavkov-Keller, T., Emmerstorfer-Augustin, A., Altijana, H., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Daniel, M., Schurmann, M., Wallner, S., Macheroux, P., Gruber, K. & Pichler, H., 15 Nov 2016.

Research output: Contribution to conferencePosterResearchpeer-review

Targeting human dipeptidyl peptidase III (hDPPIII): a therapeutic potential for safer pain management

Jha, S., Ivkovic, J., Taschler, U., Kumar, P., Zimmermann, R., Gruber, K., Breinbauer, R. & Macheroux, P., Sep 2016.

Research output: Contribution to conferencePosterResearch

The Berberine bridge enzyme-like enzyme from Physcomitrella patens

Toplak, M., Daniel, B., Wallner, S., Wiedemann, G., Reski, R. & Macheroux, P., Jul 2016.

Research output: Contribution to conferencePosterResearch

The flavodoxin-like proteins Pst2 and Ycp4 from Saccharomyces cerevisiae belong to the FMN-dependent NAD(P)H:quinone oxidoreductases

Koch, K., Hromic, A., Sorokina, M., Reisinger, M., Gruber, K. & Macheroux, P., 5 Feb 2016.

Research output: Contribution to conferencePosterResearch

The protective/regulative role of the antioxidant enzyme Irc15 on the microtubule network of S. cerevisiae

Koch, K. & Macheroux, P., 4 Jul 2016.

Research output: Contribution to conferencePosterResearch

The role of the enzyme dimethylglycine dehydrogenase in sarcosine metabolism of human prostate cancer cell lines

Augustin, P. A., Haider, M., Stracke, A., Meier-Allard, N., Meinitzer, A., Rinner, B., Macheroux, P. & Fuchs, R., 2016.

Research output: Contribution to conferencePosterResearch

Towards in vitro bioluminescence: exploiting bacterial luciferases

Brodl, E., Tabib, C. & Macheroux, P., 29 Sep 2016.

Research output: Contribution to conferencePosterResearch

Towards in vitro bioluminescence: exploiting bacterial luciferases

Brodl, E., Tabib, C. & Macheroux, P., 12 Sep 2016.

Research output: Contribution to conferencePosterResearch

Towards understanding the structural destabilization of a cancer associated variant of human NQO1

Strandback, E. S., Lienhart, W-D., Köberl, C., Hromic, A., Pletz, J., Gudipati, V., Gruber, K., Breinbauer, R. & Macheroux, P., 2016.

Research output: Contribution to conferencePosterResearch

2015

A luciferous surprise: A new natural aldehyde substrate for bacterial bioluminescence

Tabib, C., Brodl, E., Bergner, T., Ivkovic, J., Wallner, S., Breinbauer, R. & Macheroux, P., 2015.

Research output: Contribution to conferencePosterResearch

Biochemical and structural characterization of the microtubule-associated protein Irc15

Koch, K. & Macheroux, P., 2015.

Research output: Contribution to conferencePosterResearch

Biochemical and structural characterization of the microtubule-associated protein Irc15

Koch, K. & Macheroux, P., 2015.

Research output: Contribution to conferencePosterResearch

Characterization and therapeutic potential of DPP III knockout mice

Jha, S., Taschler, U., Ivkovic, J., Breinbauer, R., Zimmermann, R. & Macheroux, P., 3 Dec 2015.

Research output: Contribution to conferencePosterResearch

Characterization of DPPIII knockout mice

Jha, S., Macheroux, P., Ivkovic, J., Taschler, U., Kumar, P., Gruber, K. & Zimmermann, R., 2015.

Research output: Contribution to conferencePosterResearch

Characterization of DPP III knockout mice

Jha, S., Taschler, U., Ivkovic, J., Kumar, P., Gruber, K., Zimmermann, R. & Macheroux, P., 2015.

Research output: Contribution to conferencePosterResearch

Design and Synthesis of Inhibitors of Dipeptidyl Peptidase-III

Lembacher-Fadum, C., Ivkovic, J., Jha, S., Kumar, P., Gruber, K., Macheroux, P. & Breinbauer, R., 3 Dec 2015.

Research output: Contribution to conferencePosterResearchpeer-review

Design and Synthesis of Inhibitors of Dipeptidyl Peptidase-III

Lembacher-Fadum, C., Ivkovic, J., Jha, S., Kumar, P., Gruber, K., Macheroux, P. & Breinbauer, R., 2015.

Research output: Contribution to conferencePosterResearch

Design and Synthesis of Inhibitors of DPP3

Ivkovic, J., Kumar, P., Gruber, K., Macheroux, P. & Breinbauer, R., 2015.

Research output: Contribution to conferencePosterResearch

Exploration of the catalytic function and structure of N,N-8-amino-8-demethyl-D-riboflavin dimethyltransferase (RosA)

Tongsook, C., Uhl, M. K., Gruber, K. & Macheroux, P., 2015.

Research output: Contribution to conferencePosterResearch

Exploration of the catalytic function and structure of N,N-8-amino-8-demethyl-D-riboflavin dimethyltransferase (RosA)

Tongsook, C., Uhl, M. K., Gruber, K. & Macheroux, P., 2015.

Research output: Contribution to conferencePosterResearch

Identification and characterization of Tth-X and Pho-Y, novel members of the OYE family

Heckenbichler, K., Binter, A., Pavkov-Keller, T., Steinkellner, G., Steiner, K., Gruber, K. & Macheroux, P., 2015.

Research output: Contribution to conferencePosterResearch

Methyltransferases and intellectual disability - an NGS-Gene-Panel approach

Bernkopf, M., Windpassinger, C., Kranewitter, W., Schwarz, S., Baumgartner, M., Duba, H., Pilshofer, V., Kugler, E., Tongsook, C., Macheroux, P., Vincent, J. & Webersinke, G., 2015.

Research output: Contribution to conferencePosterResearch