Margit Winkler

Priv.-Doz. Dipl.-Ing. Dr.techn.

19992019
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Research Output 2001 2019

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Poster
2019

3-Hydroxytyrosol: A whole cell mediated Bioreduction using a type IV Carboxylate Reductase

Horvat, M. & Winkler, M., 9 Jul 2019.

Research output: Contribution to conferencePosterResearch

A Multi-Enzyme System for the In vitro Reduction of Carboxylic Acids to Aldehydes

Strohmeier, G., Schwarz, A., Eiteljörg, I., Kohrt, J., Howard, R. & Winkler, M., Jul 2019.

Research output: Contribution to conferencePosterResearch

Capsaicin Metabolite Synthesis by Fungal Cytochrome P450

Willim, M., Bachler, T., Schweda, B., Migglautsch, A. K., Glieder, A., Breinbauer, R. & Winkler, M., 14 Feb 2019.

Research output: Contribution to conferencePosterResearch

Enzyme-catalyzed synthesis of amides from nitriles

Glänzer, M., Grill, B., Schwab, H., Pogorevcnik, U., Reicher, K., Donsbach, K., Pienaar, D. & Winkler, M., Sep 2019.

Research output: Contribution to conferencePosterResearch

Optimizing the heterologous expression of the carboxylic acid reductase from Nocardia otitidiscavium for the reduction of aromatic acids

Weber, D., Patsch, D., Winkler, M., Turner, N. & Rother, D., 9 Jul 2019.

Research output: Contribution to conferencePosterResearch

Random mutagenesis of carboxylate reductase enabled by a substrate independent HT-assay

Rudroff, F., Winkler, M., Schwendenwein, D., Ressmann, A. K., Mihovilovic, M. D., Bornscheuer, U. T. & Dörr, M., Jul 2019.

Research output: Contribution to conferencePosterResearch

Structure elucidation of the carboxylate reductase from Neurospora crassa (NcCAR)

Daniel, B., Pavkov-Keller, T., Leithold, M., Gruber, K., Stolterfoht, H. & Winkler, M., 9 Jul 2019.

Research output: Contribution to conferencePosterResearch

Towards a new panel of nitrile hydratases

Grill, B., Schwab, H., Glänzer, M., Steinkellner, G., Strohmeier, G., Pogorevcnik, U., Reicher, K., Gruber, K., Donsbach, K. & Winkler, M., 26 Jun 2019.

Research output: Contribution to conferencePosterResearch

Valorization of Fatty Acids by Pichia pastoris: A Fresh Approach for Green Leaf Volatile Synthesis

Hashem, C., Steinberger, S., Stolterfoht, H., Rinnofner, C., Winkler, M. & Pichler, H., 12 Nov 2019.

Research output: Contribution to conferencePosterResearch

2018

A novel assay for the detection of carboxylic acid reductase (CAR) activity in whole cells

Schwendenwein, D., Ressmann, A. K., Mihovilovic, M. D., Bornscheuer, U. T., Dörr, M., Rudroff, F. & Winkler, M., 27 Aug 2018.

Research output: Contribution to conferencePosterResearch

Combinatorial optimization strategies to increase Human P450 catalytic Activity in whole cell

Weninger, A., Alkofer, A., Schmid, C., Bitter, J., Volpini de Maestri, A., Pranjic, M., Winkler, M. & Glieder, A., Sep 2018.

Research output: Contribution to conferencePosterResearch

Fatty Alcohols: enzymatically from Free fatty Acids

Horvat, M., Zabielska, J., Kourist, R. & Winkler, M., 3 Jul 2018.

Research output: Contribution to conferencePosterResearch

Fragrance synthesis via a chemo- & multi enzyme cascade

Rudroff, F., Winkler, M., Entner, M., Schwendenwein, D., Ressmann, A. K. & Mihovilovic, M. D., Jul 2018.

Research output: Contribution to conferencePosterResearch

Hybrid CARs (carboxylate reductases)

Stolterfoht, H., Gradischnig, D. & Winkler, M., 10 Oct 2018.

Research output: Contribution to conferencePosterResearch

Screening for new plant hydroxynitrile lyases

Winkler, M., Schwendenwein, D., Archer, R. & Rumbold, K., 2 Jul 2018.

Research output: Contribution to conferencePosterResearch

Small molecule Aldehydes from Carboxylic acid bioreduction

Horvat, M., Fiume, G., Stolterfoht, H., Schwendenwein, D., Schmidt, S. & Winkler, M., 9 Feb 2018.

Research output: Contribution to conferencePosterResearch

The ABAO assay, a new tool for Carboxylic Acid Reductase engineering

Rudroff, F., Winkler, M., Schwendenwein, D., Ressmann, A. K., Mihovilovic, M. D., Bornscheuer, U. T. & Dörr, M., Jul 2018.

Research output: Contribution to conferencePosterResearch

2017

Carboxylic Acid Reductase mediated Biotransformations

Schwendenwein, D., Fiume, G., Pichler, H. & Winkler, M., 11 Jul 2017.

Research output: Contribution to conferencePosterResearch

Cascade reactions for aldehyde generation in vivo

Schwendenwein, D., Rudroff, F. & Winkler, M., 15 Nov 2017.

Research output: Contribution to conferencePosterResearch

Catalytic Cascades – ‘En Route’ to Applied Biochemical Cell Factories

Rudroff, F., Ressmann, A. K., Schwendenwein, D., Leonhartsberger, S., Dörr, M., Mihovilovic, M. D., Bornscheuer, U. T., Winkler, M., Fink, M. J., Milker, S., Bayer, T., Wiesinger, T. & Oberleitner, N., 15 Nov 2017.

Research output: Contribution to conferencePosterResearch

Combinatorial optimization strategies to increase Human P450 catalytic Activity in whole cell Biotransformations

Weninger, A., Alkofer, A., Schmid, C., Pranjic, M., Winkler, M. & Glieder, A., Jul 2017.

Research output: Contribution to conferencePosterResearch

Concurrent optimization strategies for high level protein production: Process, strain and expression engineering

Weninger, A., Alkofer, A., Schmid, C., Höppel, E., Winkler, M. & Glieder, A., Jun 2017.

Research output: Contribution to conferencePosterResearch

Cytochrome P450 CYP505 mutants for biooxidations of active pharmaceutical ingredients

Bachler, T., Weninger, A., Glieder, A. & Winkler, M., 21 Nov 2017.

Research output: Contribution to conferencePosterResearch

Cytochrome P450 CYP505 mutants for biooxidations of active pharmaceutical ingredients

Bachler, T., Weninger, A., Glieder, A. & Winkler, M., 5 Sep 2017.

Research output: Contribution to conferencePosterResearch

Enzymatic alkene cleavage to Aldehydes and ketones

Grill, B., Pavkov-Keller, T., Trunk, S., Darnhofer, B., Schwab, H., Winkler, M., Hall, M. & Steiner, K., 15 Nov 2017.

Research output: Contribution to conferencePosterResearch

Identification of key residues in Neurospora crassa Carboxylate reductase (CAR)

Stolterfoht, H., Schwendenwein, D., Rudroff, F., Pichler, H. & Winkler, M., 11 Jul 2017.

Research output: Contribution to conferencePosterResearch

Identification of key residues in Neurospora crassa Carboxylate reductase (CAR)

Stolterfoht, H., Schwendenwein, D., Rudroff, F., Pichler, H. & Winkler, M., 15 Nov 2017.

Research output: Contribution to conferencePosterResearch

S620A Mutation in Neurospora crassa Carboxylic acid Reductase abolishes Function

Ling, J. G., Quay, D. H-X., Khalid, R. M., Murad, M. A., Winkler, M. & Bakar, F. D. A., 6 Dec 2017.

Research output: Contribution to conferencePosterResearch

Small molecule Aldehydes from Carboxylic acid bioreduction

Horvat, M., Fiume, G., Stolterfoht, H., Schwendenwein, D., Schmidt, S. & Winkler, M., 14 Nov 2017.

Research output: Contribution to conferencePosterResearch

Substrate funnelling complements flux optimization tools to maximize product titers of in vivo cascades

Bayer, T., Milker, S., Wiesinger, T., Winkler, M., Mihovilovic, M. D. & Rudroff, F., Jul 2017.

Research output: Contribution to conferencePosterResearch

Substrate specificity of CYP505X from Aspergillus fumigatus

Bachler, T., Alkofer, A., Gralewska, P., Weninger, A., Glieder, A., Breinbauer, R. & Winkler, M., 11 Jul 2017.

Research output: Contribution to conferencePosterResearch

Towards improve expression of Neurospora crassa CAR to create efficient whole cell catalysts for aldehyde preparation

Schwendenwein, D., Stolterfoht, H., Rudroff, F. & Winkler, M., 11 Jul 2017.

Research output: Contribution to conferencePosterResearch

Whole Cell Substrate Screening of Carboxylic acid Reductases

Ressmann, A. K., Stolterfoht, H., Schwendenwein, D., Mihovilovic, M. D., Winkler, M. & Rudroff, F., Jul 2017.

Research output: Contribution to conferencePosterResearch

2016

Aldehyde preparation with new fungal carboxylate reductases

Schwendenwein, D., Rudroff, F., Steiner, K., Oberhemm, P., Fiume, G. & Winkler, M., 12 Jul 2016.

Research output: Contribution to conferencePosterResearch

A new family of R-selective Hydroxynitrile lyases

Lanfranchi, E., Köhler, E-M., Diepold, M., Pavkov-Keller, T., Gruber, K., Steiner, K., Glieder, A. & Winkler, M., 11 Jul 2016.

Research output: Contribution to conferencePosterResearch

A new family of R-selective Hydroxynitrile lyases

Lanfranchi, E., Eva-Maria, K., Diepold, M., Pavkov-Keller, T., Gruber, K., Steiner, K., Glieder, A. & Winkler, M., 16 Nov 2016.

Research output: Contribution to conferencePosterResearch

A new fungal carboxylic acid reductase for the preparation of aldehydes from acids

Fiume, G., Oberhemm, P., Schwendenwein, D. & Winkler, M., 12 Sep 2016.

Research output: Contribution to conferencePosterResearch

Chemo-, regio- and stereoselectivity of carboxylic acid reductases

Winkler, C. K., Plank, M., Winkler, M. & Faber, K., 30 Aug 2016.

Research output: Contribution to conferencePosterResearch

Chemo-, regio- and stereoselectivity of carboxylic acid reductases

Winkler, C. K., Plank, M., Winkler, M. & Faber, K., 14 Nov 2016.

Research output: Contribution to conferencePosterResearch

Concurrent optimization strategies for high level protein production: Protein, strain and expression engineering

Weninger, A., Alkofer, A., Wimmer, R., Höppel, E., Eichmann, J. P-R., Schmid, C., Winkler, M. & Glieder, A., 22 Sep 2016.

Research output: Contribution to conferencePosterResearch

Convergent Carbon Flux via Substrate Funelling for the In Vivo Production of Reactive Aldehyde Species

Bayer, T., Wiesinger, T., Milker, S., Winkler, M., Rudroff, F. & Mihovilovic, M. D., 13 Jul 2016.

Research output: Contribution to conferencePosterResearch

Expression of fungal cytochrome P450 variants in E. coli and their validation for API metabolite synthesis

Bachler, T., Eichmann, J. P-R., Weninger, A., Hammer, K., Tunjic, S., Glieder, A., Breinbauer, R. & Winkler, M., 12 Sep 2016.

Research output: Contribution to conferencePosterResearch

Selective preparation of Aldehydes using carboxylate reductases

Schwendenwein, D., Oberhemm, P., Fiume, G., Rudroff, F., Steiner, K., Rudnicka, K. & Winkler, M., 16 Nov 2016.

Research output: Contribution to conferencePosterResearch

Towards API Metabolite Synthesis by Fungal Cytochrome P450 variants

Bachler, T., Eichmann, J. P-R., Weninger, A., Glieder, A., Breinbauer, R. & Winkler, M., 16 Nov 2016.

Research output: Contribution to conferencePosterResearch

Tuning the expression of Neurospora crassa carboxylic acid reductase towards an efficient whole cell catalyst for aldehyde preparation

Schwendenwein, D., Rudroff, F. & Winkler, M., 12 Sep 2016.

Research output: Contribution to conferencePosterResearch

2015

7-Cyano-7-deazaguanine synthase: a reverse Nitrilase?

Dokulil, K., Pavkov-Keller, T., Gruber, K. & Winkler, M., 2015.

Research output: Contribution to conferencePosterResearch

Biotransformations for drug metabolite synthesis

Winkler, M., Bachler, T., Geier, M., Hanlon, S. P., Eggimann, F. K., Rodrigues, D., Ferreira Antunes, M., Kittelmann, M., Glieder, A., Wirz, B. & Lütz, S., 2015.

Research output: Contribution to conferencePosterResearch

Drug Metabolizing Enzymes: From Heterologous Expression to Drug Metabolite Synthesis

Winkler, M., Bachler, T., Geier, M., Glieder, A., Hanlon, S. P., Eggimann, F. K., Rodrigues, D., Antunes, M., Kittelmann, M., Wirz, B. & Lütz, S., 2015.

Research output: Contribution to conferencePosterResearch

Enzyme catalyzed reduction of carboxylic acids

Winkler, M., 2015.

Research output: Contribution to conferencePosterResearch

The unique hydroxynitrile lyase from fern

Lanfranchi, E., Winkler, M., Pavkov-Keller, T., Köhler, E-M., Diepold, M., Darnhofer, B., Steiner, K., Thallinger, G., Birner-Grünberger, R., van Pelt, S., Gruber, K. & Glieder, A., 2015.

Research output: Contribution to conferencePosterResearch