Johannes Khinast

Univ.-Prof. Dipl.-Ing. Dr.techn.

1991 …2022
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Research Output 1991 2019

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Conference contribution
2016

The Virtual Sandbox

Wu, M., Reichel, E., Eck, J., Khinast, J. & Radl, S., 31 Mar 2016, 3rd Austrian Particle Forum.

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

File
sand
geometry
simulation
project
public
2015

Bioreactor Simulation with CUDA

Witz, C. & Khinast, J., 2015, 7th International Berlin Workshop - IBW7 on Transport Phenomena with Moving Boundaries and More 30th-31st October 2014. p. 91-105 (Fortschritt-Berichte VDI Reihe 3 Verfahrenstechnik; no. 947).

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Carrier-based Dry Powder Inhalation Part I: Impact of Carrier Modification on Capsule Filling Processability and in vitro Aerodynamic Performance

Zellnitz, S., Faulhammer, E., Wahl, V., Paudel, A. & Khinast, J., 2015, (Accepted/In press) Drug Delivery to the Lungs - DDL26 - Book of abstracts. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Carrier-based Dry Powder Inhalation Part II: Impact of carrier material and API processing on the inter-particulate surface interactions in adhesive mixtures for inhalation

Zellnitz, S., Faulhammer, E., Wahl, V., Khinast, J. & Paudel, A., 2015, (Accepted/In press) Drug Delivery to the Lungs - DDL26 - Book of abstracts. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Detailed Understanding of the Blending of Wet Powders and the Liquid Distribution Therein

Wu, M., Mohan, B., Khinast, J. & Radl, S., 17 Mar 2015, ProcessNet, Vortragsprogramm Grenzflächenbestimmte Systeme und Prozesse, Magdeburg,2015. Magdeburg

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Powders
Liquids
Granulation
Direct numerical simulation
Finite difference method

EXTRACTABLES AND LEACHABLES FROM FILTER MATERIAL AND THEIR IMPACT ON PROTEIN FORMULATION

Wahl, V., Wieser, J., Mohr, S., Khinast, J. & Paudel, A., 2015, Programme & Abstracts. Ghent: ., p. 114-115

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Micro-Pelletizing of Pharmaceutical HME Formulations Using a Die Face Pelletizer

Witschnigg, A., Koscher, G., Treffer, D. F., Mürb, R., Laske, S. & Khinast, J., 2015, (Accepted/In press) Polymer Processing Society 2015. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Moisture induced changes in secondary structure and crystallinity of human fibrinogen powders

Wahl, V., Scheibelhofer, O., Rößl, U., Leitgeb, S., deBeer, T. & Khinast, J., 2015, Abstracts Poster. Vienna: ., p. 186-187

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Prozessentwicklung zur Herstellung schmelzextrudierter pharmazeutischer Produkte

Treffer, D. F., Hörmann, T., Koscher, G. & Khinast, J., 3 Dec 2015, Konferenzband: 41. Deutsche Compoundiertagung - Prozessoptimierung an Compoundieranlagen. Nürnberg

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Transport of Liquids in Unsaturated Bi- and Polydisperse Particle Beds

Wu, M., Mohan, B., Khinast, J. & Radl, S., 8 Nov 2015, AIChe Annual Meeting. Salt Lake City, (USA)

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Open Access
File
beds
liquids
direct numerical simulation
liquid bridges
simulation
2014

A Novel Simulation Approach for Hot Melt Extrusion

Eitzlmayr, A., Matic, J., Koscher, G. & Khinast, J., 2014, Book of Abstracts. Graz: ., p. 21-21

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Comparative Study of the Accuracy of a DNS Solver for Fluid-Gas-Particle Flow Simulation

Wu, M., Khinast, J. & Radl, S., 2014, Minisymposium Verfahrenstechnik. Vienna University of Technology: TU Wien, Institute of Chemical Engineering and chemical-engineering.at(ZVR 708660229), p. 158-161 (Simulation).

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Open Access
File

Die Face Pelletizing of Sticky HME Formulations

Treffer, D. F., Koscher, G. & Khinast, J., 2014, (Accepted/In press) Conference Proceedings. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Die Face Pelletizing of Sticky HME Formulations

Treffer, D. F., Koscher, G. & Khinast, J., 2014, 6th International Congress on Pharmaceutical Engineering - Book of Abstracts. ., p. 7-7

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Direct Simulation of Film Flow on Spheres to Investigate Liquid Bridge Formation

Wu, M., Khinast, J. & Radl, S., 17 Nov 2014, AIChE Annual Meeting 2014. Atlanta, (USA)

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Multi-species multi-phase simulation of medium sized bioreactor with les using Lattice-Boltzmann Equations

Prakash, A., Witz, C., Radl, S. & Khinast, J., 2014, Engineering Sciences and Fundamentals 2014 - Core Programming Area at the 2014 AIChE Annual Meeting. American Institute of Chemical Engineers, Vol. 2. p. 984-986 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Optical coherence tomography data processing for in-line monitoring of a pharmaceutical film-coating process

Markl, D., Hannesschläger, G., Sacher, S., Buchsbaum, A. & Khinast, J., 2014, Proceedings of the 10th Minisymposium Verfahrenstechnik. ., p. 142-145

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Real-time data processing for in-line monitoring of a pharmaceutical coating process by optical coherence tomography

Markl, D., Ziegler, J., Hannesschläger, G., Sacher, S., Buchsbaum, A., Leitner, M. & Khinast, J., 2014, Biophotonics: Photonic Solutions for Better Health Care IV. ., Vol. 9129. p. 1-12 (Proceeding of SPIE).

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Scale−Bridging Models for Transfer of Liquid in Dense Particle Beds

Mohan, B., Wu, M., Sundaresan, S., Khinast, J. & Radl, S., 16 Nov 2014, AIChE Annual Meeting. Atlanta, (USA)

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Open Access
File

Scaling up a Capsule Filling Process for Inhalation Dosage Forms

Llusa, M., Faulhammer, E., Khinast, J., Lawrence, S., Biserni, S. & Calzolari, V., 2014, (Accepted/In press) Scaling up a Capsule Filling Process for Inhalation Dosage Forms. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

The effects of powder compressibility and the ratio between the powder bed’s height and the length of the dosing chamber on plug densification

Llusa, M., Faulhammer, E., Khinast, J., Lawrence, S., Biserni, S. & Calzolari, V., 2014, (Accepted/In press) The effects of powder compressibility and the ratio between the powder bed’s height and the length of the dosing chamber on plug densification. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

The influence of residual water on the secondary structure and crystallinity of freeze dried fibrinogen

Wahl, V., Scheibelhofer, O., Rößl, U., Leitgeb, S., deBeer, T. & Khinast, J., 2014, Book of Abstracts. ., p. 22-23

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

The Simulation of Mixing and Free Surface Flows in Co-Rotating Twin-Screw Extruders

Eitzlmayr, A., Kondor, I., Matic, J., Koscher, G. & Khinast, J., 2014, 2014 AIChE Annual Meeting Conference Proceedings. ., p. 0-0

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Towards A Refined Model for Liquid Bridge Volume Between Wet Particles

Wu, M., Khinast, J. & Radl, S., 20 Jul 2014, 11th World Congress on Computation Mechanics (WCCM XI). Barcelona, Spain

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

2013

A multipoint measurement spectrometer for monitoring pharmaceutical processes

Scheibelhofer, O., Sacher, S., Menezes, J. C., Kerschhaggl, P. & Khinast, J., 2013, NIR 2013 Proceedings. ., p. 393-396

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

A New Boundary Treatment for Complex Geometries in Smoothed Particle Hydrodynamics

Eitzlmayr, A., Radl, S., Kloss, C., Koscher, G. & Khinast, J., 2013, 2013 AIChE Annual Meeting Conference Proceedings. ., p. 0-0

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Bioreactor simulation with Cuda

Witz, C., Tantikul, T. & Khinast, J. G., 1 Jan 2013, North American Mixing Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. American Institute of Chemical Engineers, p. 32-33 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Generic Drugs
Bioreactors

Bioreactor simulation with CUDA

Witz, C., Tantikul, T. & Khinast, J., 1 Jan 2013, Pharmaceutical Discovery, Development and Manufacturing Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. American Institute of Chemical Engineers, p. 67-68 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Bioreactors
Equipment and Supplies
Generic Drugs
Buoyancy
Bubbles (in fluids)

Correlation of conductive flux and Contact stress - Lessons learned from Simple shear

Mohan, B., Radl, S. & Khinast, J., 2013, 9. Minisymposium der Verfahrenstechnik. ., p. 102-104

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Open Access
File

Einfluss des Restwassergehaltes auf das Aggregationsverhalten lyophilisierter Proteinbatches

Wahl, V., Piller, M., Leitgeb, S. & Khinast, J., 2013, Book of Abstracts. ., p. 231-233

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Injection Moulding as a One-Stop-Production to Produce Pharmaceutical Dosage Forms

Treffer, D. F., Eggenreich, K., Schrank, S., Koscher, G., Roblegg, E. & Khinast, J., 2013, (Accepted/In press) Conference Proceedings. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Manufacturing of Low Fill Weight Capsules Using a Nozzle Dosator Capsule Filling Machine

Llusa, M., Faulhammer, E., Khinast, J., Lawrence, S., Biserni, S., Calzolari, V. & Fink, M., 2013, (Accepted/In press) Manufacturing of Low Fill Weight Capsules Using a Nozzle Dosator Capsule Filling Machine. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Nano-Extrusion: Herstellung einer festen nanopartikulären Formulierung durch das Verarbeiten von Nanosuspensionen mittels Schmelzextrusion

Baumgartner, R., Khinast, J. & Roblegg, E., 2013, 9. Minisymposium Verfahrenstechnik, 17.04.-18.04.2013, Montanuniversität Leoben, Book of Abstracts. Leoben: Verlag der Montanuniversität Leoben, p. 97-101

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Open Access
File

Optical coherence tomography for non-destructive analysis of coatings in pharmaceutical tablets

Markl, D., Hannesschläger, G., Sacher, S., Khinast, J. & Leitner, M., 2013, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials. Ferraro, P. (ed.). ., Vol. 8792. p. 879202-879202 (SPIE Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Simulation of Mixing in Hot Melt Extruders Using Smoothed Particle Hydrodynamics

Eitzlmayr, A., Radl, S., Koscher, G. & Khinast, J., 2013, North American Mixing Forum 2013 - Core Programming Area at the 2013 AIChE Annual Meeting. American Institute of Chemical Engineers, p. 66-67

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

The Effect of the Ratio between the Powder Bed’s Height and the Length of the Dosing Chamber and the Speed of Capsule Filling on Plug Density and Capsule Weight Variability

Llusa, M., Faulhammer, E., Khinast, J., Scharrer, G., Lawrence, S., Biserni, S. & Calzolari, V., 2013, (Accepted/In press) The Effect of the Ratio between the Powder Bed’s Height and the Length of the Dosing Chamber and the Speed of Capsule Filling on Plug Density and Capsule Weight Variability. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Untersuchung des Einflusses von Alkohol auf lipophile schmelzextrudierte Pellets

Jedinger, N., Koscher, G., Khinast, J. & Roblegg, E., 2013, 9. Minisymposium der Verfahrenstechnik, 17. und 18. April 2013, Montanuniversität Leoben, Book of Abstracts. Leoben: Verlag der Montanuniversität Leoben, p. 138-142

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

2012

Analysis of drug-packaging interactions via molecular dynamics (MD) simulation

Feenstra, P., Brunsteiner, M. & Khinast, J., 2012, Extractables & Leachables Europe 2012. Shawbury, Shrewsbury, Shropshire SY4 4NR, UK: Smithers Information Ltd., p. 12-1-12-10

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Characterizing critical protein powder parameters for optimization of further processing

Wahl, V., Leitgeb, S. & Khinast, J., 2012, Book of Abstracts. ., p. 137-140

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Continuous Pharmaceutical Hot-Melt Extrusion & Hot-Die Face Pelletizing

Treffer, D. F., Eitzlmayr, A., Smola, C-M., Koscher, G., Roblegg, E. & Khinast, J., 2012, (Accepted/In press) 2012 AIChE Annual Meeting. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Continuous Powder Flow Monitoring via Near-Infrared Hyperspectral Imaging

Scheibelhofer, O., Koller, D. M., Kerschhaggl, P. & Khinast, J., 2012, 2012 IEEE International Instrumentation and Measurement Technology Conference (I2MTC 2012) Proceedings. ., p. 748-753

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Funktionalisierte mesoporöse Monolithen für kontinuierliche Ringspalt-Elektrochromatographie

Braunbruck, M-G., Gruber-Wölfler, H., Feenstra, P., Laskowski, R., Bart, H-J. & Khinast, J., 2012, Chemie Ingenieur Technik Special Issue: ProcessNet-Jahrestagung 2012 und 30. Jahrestagung der Biotechnologen. Weinheim: Wiley-VCH , p. 1400-1400

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Hot Melt Extrusion: Product and Process Development

Eitzlmayr, A., Treffer, D. F., Jedinger, N., Koscher, G., Roblegg, E. & Khinast, J., 2012, Abstract Book. Lisbon: self-published, p. 70-71

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Modeling of Co-Rotating Twin Screw Extrusion

Eitzlmayr, A. & Khinast, J., 2012, 8. Minisymposium Verfahrenstechnik, 2. Mai 2012, JKU Linz, Book of Abstracts. Linz: Verlag der Johannes Kepler Unversität Linz, p. 94-98

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

PAT Solution for Inline Content Homogeneity Monitoring with NIR for Pharmaceutical Hot Melt Extrusion

Wahl, P., Markl, D., Treffer, D. F., Koscher, G., Roblegg, E. & Khinast, J., 2012, Book of Abstracts 8. Minisymposium. ., p. 71-74

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Predictive Modeling of Hot Melt Extruders

Eitzlmayr, A., Treffer, D. F., Hörl, G., Windhab, S., Koscher, G. & Khinast, J., 2012, 2012 AIChE Annual Meeting Conference Proceedings. ., p. 0-0

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Reversed phase monolithic stationary phases for defined separation tasks in Continuous Annular Electro-Chromatography

Braunbruck, M-G., Gruber-Wölfler, H., Feenstra, P., Khinast, J., Laskowski, R. & Bart, H-J., 2012, Book of Abstracts. Linz: ., p. 92-93

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Scale-up of Capsule Filling Operations Using a Nozzle-Dosator Machine

Llusa, M., Faulhammer, E., Khinast, J., Scharrer, G., Lawrence, S., Biserni, S. & Calzolari, V., 2012, (Accepted/In press) Scale-up of Capsule Filling Operations Using a Nozzle-Dosator Machine. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Separation, hydrodynamics and heating effects in continuous annular electro-chromatography (CAEC)

Laskowski, R., Bart, H-J., Gruber-Wölfler, H., Feenstra, P., Braunbruck, M-G. & Khinast, J., 2012, International Congress of Chemical and Process Engineering. ., p. 1755-1772

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Understanding the effects of powder and wall material properties on weight variability during capsule filling

Llusa, M., Khinast, J., Faulhammer, E., Lawrence, S., Calzolari, V., Biserni, S. & Scharrer, G., 2012, (Accepted/In press) Understanding the effects of powder and wall material properties on weight variability during capsule filling. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review