Helmut Schwab

Univ.-Prof.i.R. Dipl.-Ing. Dr.techn.

1981 …2019
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Research Output 1981 2019

2009

PharmaPLE - a versatile tool for biocatalytic synthesis of pharmaceuticals

Kietzmann, M., Hermann, M., Braun, A., El Heliebi, A., Winkler, C., Gruber, K., Szabo, O., May, O., Schwab, H. & Pichler, H., 29 Apr 2009.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Pig Liver Esterase: An old enzyme made fit for broad industrial applications by molecular engineering

Schwab, H., Kietzmann, M., Pichler, H., Winkler, C., Braun, A., Szabo, O., Gruber, K., Luiten, R., Skranc, W., May, O., El-Helibi, A. & Steinkellner, G., 21 Sep 2009.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Preparation of an Esterase

Kietzmann, M., Schwab, H., Pichler, H., Ivancic, M., May, O. & Luiten, R. G. M., 8 Jan 2009, Patent No. WO 2009/004093 A1

Research output: PatentResearch

Sequencing and Annotating Pichia pastoris CBS7435

Küberl, A., Thallinger, G., Schwab, H. & Pichler, H., 2009.

Research output: Contribution to conferencePosterResearch

The SGNH-hydrolase of Streptomyces coelicolor has (aryl)esterase and a true lipase activity

Schwab, H., Bielen, A., Vujaklja, D., Abramic, M., Cetkovic, H. & Long, P., 2009, In : Biochimie. 91, p. 390-400

Research output: Contribution to journalArticleResearchpeer-review

2008

Alternative pig liver esterase (APLE) - Cloning, identification and functional expression in Pichia pastoris of a versatile new biocatalyst

Hermann, M., Kietzmann, M. U., Ivancic, M., Zenzmaier, C., Luiten, R., Skranc, W., Wubbolts, M., Winkler, M., Birner-Grünberger, R., Pichler, H. & Schwab, H., 2008, In : Journal of Biotechnology. 133, p. 301-310

Research output: Contribution to journalArticleResearchpeer-review

Alternative Pig Liver Esterase (APLE) - Improving the yield

Kietzmann, M., Hermann, M., Hajek, T., Ivancic, M., Pichler, H., Schwab, H., Skranc, W., May, O. & Luiten, R., 2008.

Research output: Contribution to conferencePosterResearch

A Two-step Method for Covalently Immobilizing Enzymes on Silicon Surfaces

Schider, G., Gruber-Wölfler, H., Jeanquartier Claire, N. V., Feichtenhofer, S., Schwab, H., Koch, H. P., Schennach, R. & Khinast, J., 16 May 2008.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

A two-step method to covalently bind biomolecules to group IV semiconductors: Si(111)/1,2-Epoxi-9-decene/Esterase

Jeanquartier, C., Schider, G., Feichtenhofer, S., Schwab, H., Schennach, R., Stettner, J., Winkler, A., Gruber-Wölfler, H., Schitter, G., Eder, R. J-P. & Khinast, J., 2008, In : Langmuir. 24, p. 13957-13961

Research output: Contribution to journalArticleResearchpeer-review

First multi-ton application of recombinant porcine liver esterase

Kietzmann, M., May, O., Hermann, M., Luiten, R., Kierkels, H., Skranc, W., Schwab, H. & Pichler, H., 2008.

Research output: Contribution to conferencePosterResearch

Improvement of a stereoselective biocatalytic synthesis by substrate and enzyme engineering: 2-hydroxy-(4×-oxocyclohexyl)acetonitrile as the model

Avi, M., Wiedner, R., Griengl, H. & Schwab, H., 2008, In : Chemistry - A European Journal. 14, 36, p. 11415-11422

Research output: Contribution to journalArticleResearchpeer-review

Methyltransferases for novel biocatalytic C-C bond formations

Tengg, M., Gruber, M., Stecher, H., Hermann-Krauss, C., Remler, P., Schwab, H. & Griengl, H., 2008.

Research output: Contribution to conferencePosterResearch

Methyltransferases for Novel Biocatalytic C-C Bond Formations

Gruber, M., Tengg, M., Stecher, H., Hermann-Krauss, C., Remler, P., Schwab, H. & Griengl, H., 2008.

Research output: Contribution to conferencePosterResearch

2007

Alternative pig liver esterase (APLE): Discovery and functional expression of a high-value biocatalyst

Kietzmann, M. U., Hermann, M., Ivancic, M., Zenzmaier, C., Hajek, T., Szabo, O., Skranc, W., May, O., Luiten, R., Pichler, H. & Schwab, H., 2007, ECB13. ., p. 215-215

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Alternative pig liver esterase (APLE): Discovery and functional expression of a high-value biocatalyst

Kietzmann, M. U., Hermann, M., Ivancic, M., Zenzmaier, C., Skranc, W., May, O., Luiten, R., Pichler, H. & Schwab, H., 2007.

Research output: Contribution to conferencePosterResearch

An efficient plasmid vector for expression cloning of large numbers of PCR fragments in Escherichia coli

Reisinger, C., Kern, A., Fesko, K. & Schwab, H., 2007, In : Applied Microbiology and Biotechnology. 77, 1, p. 241-244

Research output: Contribution to journalArticleResearchpeer-review

A novel screening assay for hydroxynitrile lyases suitable for high-throughput screening.

Schwab, H., 2007, In : Journal of Biotechnology. 129, p. 151-161

Research output: Contribution to journalArticleResearchpeer-review

Engineering of HNL from Heveo brasiliensis for improved activity on unfavourable subtrates

Wiedner, R., Avi, M., Schwab, H. & Griengl, H., 2007.

Research output: Contribution to conferencePosterResearch

Enzyme technology and biocatalysis

Nidetzky, B. & Schwab, H., 2007, In : Journal of Biotechnology. p. 1-2

Research output: Contribution to journalArticleResearchpeer-review

Heterogene Biokatalyse: Enzyme auf Si(111)

Jeanquartier, C., Schider, G., Gruber-Wölfler, H., Feichtenhofer, S., Schwab, H., Koch, H. P., Schennach, R. & Khinast, J., 17 Dec 2007.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Heterogene Biokatalyse: Enzyme auf Si(111)

Jeanquartier, C., Schider, G., Gruber-Wölfler, H., Feichtenhofer, S., Schwab, H., Koch, H. P., Schennach, R. & Khinast, J., 2007, Fortschritte in der Arzneimittelforschung. ., p. 11-11

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Highly enantioselective enzymatic cyanohydrin formation in succession to Diels-Alder reactions

Avi, M., Wiedner, R., Fechter, M., Schwab, H. & Griengl, H., 2007.

Research output: Contribution to conferencePosterResearch

Inverting enantioselectivity of Burkholderia gladioli esterase EstB by directed and designed evolution.

Ivancic, M., Valinger, G., Gruber, K. & Schwab, H., 2007, In : Journal of Biotechnology. 129, 1, p. 109-122

Research output: Contribution to journalArticleResearchpeer-review

Method for preparing enantiomerically enriched 2-alkyl-5-halopent-4-enecarboxylic acids and -carboxylic esteras

Steinbauer, G., Stanek, M., Pojarliev, P., Skranc, W., Wubbolts, M., Schwab, H., Kierkels, J., Pichler, H., Hermann, M. & Zenzmaier, C., 5 Jul 2007, Patent No. WO 2007/073846 A1

Research output: PatentResearch

Micro-colony array based high throughput platform for enzyme library screening

Pohn, B., Gerlach, J., Scheideler, M., Katz, H., Uray, M., Bischof, H., Klimant, I. & Schwab, H., 2007, In : Journal of Biotechnology. 129, p. 162-170

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Novel Polypeptide having esterase activity and recombinant esterase and use thereof

Steinbauer, G., Stanek, M., Pojarliev, P., Skranc, W., Schwab, H., Wubbolts, M., Kierkels, J., Pichler, H., Hermann, M. & Zenzmaier, C., 5 Jul 2007, Patent No. WO 2007/073847

Research output: PatentResearch

Novel Polypeptide having esterase activity and recombinant esterase and use thereof

Steinbauer, G., Stanek, M., Pojarliev, P., Skranc, W., Schwab, H., Wubbolts, M., Kierkels, J., Pichler, H., Hermann, M. & Zenzmaier, C., 5 Jul 2007, Patent No. WO 2007/073845 A2

Research output: PatentResearch

Random strand transfer recombination (RSTR) for homology-independent nucleic acid recombination

Reiter, B., Faschinger, A., Glieder, A. & Schwab, H., 2007, In : Journal of Biotechnology. 129, 129 (1), p. 39-49

Research output: Contribution to journalArticleResearchpeer-review

Screening of endophytic metagenomic libraries using Bacillus species as hosts

Breitschädel, R., Feichtenhofer, S., Nikolic, B., Sessitsch, A. & Schwab, H., 2007.

Research output: Contribution to conferencePosterResearch

Stability and activity improvement of cephalosporin esterase EstB from Burkholderia gladioli by directed evolution and structural interpretation of muteins.

Valinger, G., Hermann, M., Wagner, UG. & Schwab, H., 2007, In : Journal of Biotechnology. p. 98-108

Research output: Contribution to journalArticleResearchpeer-review

Synthesis, transport and function of glucosylglycerol in Stenotrophomonas

Zahrl, D., Schwab, H., Nidetzky, B., Hagemann, M. & Berg, G., 2007.

Research output: Contribution to conferencePosterResearch

Synthesis, transport and function of glucosylglycerol in Stenotrophomonas

Zahrl, D., Schwab, H., Nidetzky, B., Hagemann, M. & Berg, G., 17 Oct 2007.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

2006

2-D solid-state assay platform: a tool for screening aldehyde-releasing enzyme activity in colonies

Gerlach, J., Reisinger, C., Pohn, B., Schwab, H. & Klimant, I., 2006, In : Microchimica acta. 156, 3-4, p. 209-218

Research output: Contribution to journalArticleResearchpeer-review

A versatile colony assay based on NADH fluorescence

Reisinger, C., van Assemab, F., Schuermann, M., Hussain, Z., Remler, P. & Schwab, H., 2006, In : Journal of molecular catalysis / B. 39, p. 149-155

Research output: Contribution to journalArticleResearchpeer-review

Cell surface expression of bacterial esterase A by Saccharomyces cerevisiae and its enhancement by constitutive activation of the cellular unfolded protein response.

Breinig, F., Diehl, B., Rau, S., Zimmer, C., Schwab, H. & Schmitt, M. J., 2006, In : Applied and Environmental Microbiology. 72, 11, p. 7140-7147

Research output: Contribution to journalArticleResearchpeer-review

Multistep Synthesis of Enantioenriched Cyanohydrins an α-Hydroxy carboxylic Acids from Diels-alder Adducts

Avi, M., Fechter, M., Wiedner, R., Schwab, H. & Griengl, H., 9 Jul 2006.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Nitrile hydrolysis activity of Rhodococcus erythropolis NCIMB 11540 whole cells.

Vink, MK., Wijtmans, R., Reisinger, C., Van den Berg, RJ., Shortinghuis, CA., Schwab, H., Shoemaker, HE. & Rutjes, FP., 2006, In : Journal of Biotechnology. May, 1(5), p. 569-573

Research output: Contribution to journalArticleResearchpeer-review

Planar optical sensors: A tool for screening enzyme activity in high density cell arrays

Gerlach, J., Pohn, B., Karl, W., Scheideler, M., Uray, M., Bischof, H., Schwab, H. & Klimant, I., 2006, In : Sensors and Actuators / B, Chemical. 114, 2, p. 984-994

Research output: Contribution to journalArticleResearchpeer-review

2005

Analysis of cell arrays: A tool for evaluation of high density micro colony chips in fluescence assays

Uray, M., Bischof, H., Gerlach, J., Klimant, I., Pohn, B. & Schwab, H., 6 Jun 2005.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Analysis of Cell Arrays: A Tool for Evaluation of High Density Micro Colony Chips in Fluorescence Assays

Uray, M., Gerlach, J., Pohn, B., Bischof, H., Klimant, I. & Schwab, H., 2005, (Submitted) Prague Post Genome Technology Workshop. .

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Application of Ionic Liquids in the Synthesis of Lactate from Oxalate and Acetaldehyde Using a One-Pot Bi-Enzymatic Approach

Steinreiber, J., Reisinger, C., Schwab, H., Remler, P. & Griengl, H., 16 Mar 2005.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Application of L/D-Threonin Aldolase in the Synthesis of Long-Chain ß-Hydroxy-L-Amino-Acids,

Steinreiber, J., Reisinger, C., Schwab, H., Remler, P., Schürmann, M., van Assema, F., Wubbolts, M., Skranc, W. & Griengl, H., 3 Jul 2005.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Applicaton of L/D-threonine Aldolase in the Synthesis of Phenylserine-Derivatives

Steinreiber, J., Reisinger, C., Remler, P., Schwab, H., Schürmann, M., van Assema, F. & Griengl, H., 17 Jul 2005.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Cloning and comparison of enzyme activity of bacterial Penicillin V acylases

Gruber, K., Luschnig, D., Plank, H., Remler, P., Ribitsch, D., Steinreiber, A., Riethorst, W. & Schwab, H., 19 Jun 2005.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Development of a microscope-based screening plattform for the measurement of enzyme activities in single bacterial cells

Pritej, K., Chojnacki, P., Klimant, I. & Schwab, H., 26 May 2005.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Diels-Alder Adducts as Substrates for HNL Catalysed Cyanohydrin Reactions

Avi, M., Fechter, M., Wiedner, R., Schwab, H. & Griengl, H., 11 Dec 2005.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Diels-Alder Adducts as Substrates for HNL Catalysed Cyanohydrin Reactions

Avi, M., Fechter, M., Wiedner, R., Schwab, H. & Griengl, H., 2005.

Research output: Contribution to conferencePosterResearch

High throughput micro colony array screening with planar optical sensors

Gerlach, J., Pohn, B., Remler, P., Scheideler, M., Uray, M., Bischof, H., Klimant, I. & Schwab, H., 2005.

Research output: Contribution to conferencePosterResearch

High throughput micro colony arry screening with planar optical sensors

Gerlach, J., Pohn, B., Remler, P., Karl, W., Scheideler, M., Uray, M., Bischof, H., Schwab, H. & Klimant, I., 2005.

Research output: Contribution to conferencePosterResearch