Helmut Schwab

Univ.-Prof.i.R. Dipl.-Ing. Dr.techn.

1981 …2019
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Research Output 1981 2019

2014

Production of the sesquiterpenoid (+)-nootkatone by metabolic engineering of Pichia pastors

Wriessnegger, T., Augustin, P. A., Engleder, M., Leitner, E., Müller, M., Kaluzna, I., Schürmann, M., Mink, D., Zellnig, G., Schwab, H. & Pichler, H., 2014, In : Metabolic engineering. 24, p. 18-29

Research output: Contribution to journalArticleResearchpeer-review

Protein expression in Pichia pastoris: recent achievements and perspectives for heterologous protein production

Mudassar, A., Hirz, M., Pichler, H. & Schwab, H., 2014, In : Applied Microbiology and Biotechnology. 98, p. 5301-5317

Research output: Contribution to journalArticleResearchpeer-review

Structural and biochemical characterization of two novel enzymes with promiscuous ene-reductase activity

Pavkov-Keller, T., Binter, A., Steinkellner, G., Gruber, C. C., Steiner, K., Winkler, C., Schwab, H., Faber, K., Macheroux, P. & Gruber, K., 2014.

Research output: Contribution to conferencePosterResearch

The potential of enzymes with cupin fold in biocatalysis

Steiner, K. & Schwab, H., 31 Aug 2014.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Versatile and stable vectors for efficient gene expression in Ralstonia eutropha H16

Gruber, S., Hagen, J., Schwab, H. & Köfinger, P., 2014, In : Journal of Biotechnology. 186, p. 74-82

Research output: Contribution to journalArticleResearchpeer-review

2013

A medium-throughput-screening method for the detection of the conversion of ketones by omega-transaminases

Steiner, K., Schurmann, M., Midl, J., De Wildeman, S., Remler, P. & Schwab, H., 2013.

Research output: Contribution to conferencePosterResearch

A newly discovered multifunctional alpha2,3-sialyltransferase from Pasteurella dagmatis carries a natural Ser-to-Thr substitution

Schmoelzer, K., Ribitsch, D., Czabany, T., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 7 Jul 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Open Access
File

A newly discovered multifunctional α2,3-sialyltransferase from Pasteurella dagmatis PdST carries a natural Ser-to-Thr substitution

Czabany, T., Schmoelzer, K., Ribitsch, D., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 13 Oct 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

A newly discovered multifunctional α2,3-sialyltransferase from Pasteurella dagmatis PdST carries a natural Ser-to-Thr substitution

Schmoelzer, K., Ribitsch, D., Czabany, T., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 10 Sep 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Biochemical and structural characterization of a novel bacterial manganese-dependent hydroxynitrile lyase

Hajnal, I., Lyskowski, A. F., Hanefeld, U., Gruber, K., Schwab, H. & Steiner, K., 2013, In : The FEBS journal. 280, 22, p. 5815-5828

Research output: Contribution to journalArticleResearchpeer-review

Carboxylate reductase - a novel route for 3-hydroxytyrosol production

Napora, K., Sonavane, M. N., Plewka, J., Pomorska, D. K., Robins, K., Osorio-Lozada, A., Steiner, K., Schwab, H. & Winkler, M., 2013.

Research output: Contribution to conferencePosterResearch

Open Access
File

Characterization of a multifunctional alpha2,3-sialyltransferase from Pasteurella dagmatis, carrying a natural Ser-to-Thr substitution

Schmoelzer, K., Ribitsch, D., Czabany, T., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 2013.

Research output: Contribution to conferencePosterResearch

Characterization of a multifunctional α2,3-sialyltransferase from Pasteurella dagmatis

Schmoelzer, K., Ribitsch, D., Czabany, T., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 2013, In : Glycobiology. 23, 11, p. 1293-1304

Research output: Contribution to journalArticleResearchpeer-review

Characterization of a multifunctional α2,3-sialyltransferase from Pasteurella dagmatis, carrying a natural Ser-to-Thr substitution

Schmoelzer, K., Ribitsch, D., Czabany, T., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 2013.

Research output: Contribution to conferencePosterResearch

Cupins, a versatile family of metalloenzymes

Steiner, K., Hajnal, I. & Schwab, H., 2013.

Research output: Contribution to conferencePosterResearch

Cupins as scaffolds for novel activities

Steiner, K., Hajnal, I. & Schwab, H., 2013.

Research output: Contribution to conferencePosterResearch

De novo production of flavor compounds by engineered yeasts

Wriessnegger, T., Emmerstorfer, A., Engleder, M., Müller, M., Kaluzna, I., Schwab, H. & Pichler, H., 2013.

Research output: Contribution to conferencePosterResearch

Discovery of new and improved hydroxynitrile lyases belonging to the cupin superfamily

Wiedner, R., Kothbauer, B., Steiner, K., Gruber, M. & Schwab, H., 2013.

Research output: Contribution to conferencePosterResearch

Fusion of binding-domains to Thermobifida cellulosilytica cutinase to tune sorption characteristics and enhancing PET hydrolysis

Ribitsch, D., Antonio, O. Y., Zitzenbacher, S., Wu, J., Nowitsch, S., Steinkellner, G., Greimel, K. J., Aleš, D., Oberdorfer, G., Gruber, C., Gruber, K., Schwab, H., Karin, S-K., Herrero Acero, E. & Gübitz, G., 2013, In : Biomacromolecules. 14, 6, p. 1769–1776

Research output: Contribution to journalArticleResearchpeer-review

Homologous and heterologous expression of dehydrogenases and oxidoreductases of Ralstonia eutropha H16

Köfinger, P., Magomedova, Z., Zach, C. & Schwab, H., 2013.

Research output: Contribution to conferencePosterResearch

Increasing polyesterase activity towards synthetic polymers by diverse molecular approaches

Herrero Acero, E., Ribitsch, D., Hårnvall, K., Steinkellner, G., Gruber, K., Schwab, H. & Gübitz, G., 2013.

Research output: Contribution to conferencePosterResearch

Investigation of one-enzyme systems in the w-transaminase-catalyzed synthesis of chiral amines

Fesko, K., Steiner, K., Breinbauer, R., Schwab, H., Schürmann, M. & Strohmeier, G., 2013, In : Journal of molecular catalysis / B. 96, p. 103-110

Research output: Contribution to journalArticleResearchpeer-review

Metagenome analyses reveal the influence of the inoculant Lactobacillus buchneri CD034 on the microbial community involved in grass ensiling

Eikmeyer, F. G., Köfinger, P., Poschenel, A., Jünemann, S., Zakrzewski, M., Heinl, S., Mayrhuber, E., Grabherr, R., Pühler, A., Schwab, H. & Schlüter, A., 2013, In : Journal of Biotechnology. 167, 3, p. 334-343

Research output: Contribution to journalArticleResearchpeer-review

Methyltransferase NovO - a Versatile Catalyst for Enzymatic Friedel-Crafts Alkylation

Tengg, M., Stecher, H., Remler, P., Schwab, H. & Gruber, M., 2013.

Research output: Contribution to conferencePosterResearch

Novel enone-reductases identified by database mining for catalytic promiscuity

Steinkellner, G., Gruber, C., Steiner, K., Winkler, C., Pavkov-Keller, T., Binter, A., Lyskowski, A., Schwamberger, O., Oberer, M., Schwab, H., Faber, K., Macheroux, P. & Gruber, K., 2013.

Research output: Contribution to conferencePosterResearch

Probing the secretory pathway of the yeast Pichia pastoris

Winkler, C., Ahmad, M., Neugebauer, P., Schwab, H. & Pichler, H., 9 Oct 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Probing the secretory pathway of the yeast Pichia pastoris

Winkler, C., Mudassar, A., Neugebauer, P., Schwab, H. & Pichler, H., 2013.

Research output: Contribution to conferencePosterResearch

Probing the secretory pathway of the yeast Pichia pastoris

Winkler, C., Ahmad, M., Neugebauer, P., Schwab, H. & Pichler, H., 2013, Book of abstracts. Zagreb: Recedo, d.o.o., Zagreb, p. 38-38

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Rec. ST6Gal-I variants to control enzymatic activity in processes of in vitro glycoengineering

Engel, A. M., Sobek, H., Greif, M., Malik, S., Thomann, M., Jung, C., Reusch, D., Ribitsch, D., Zitzenbacher, S., Luley, C., Schmoelzer, K., Czabany, T., Nidetzky, B., Schwab, H. & Mueller, R., 2013.

Research output: Contribution to conferencePosterResearch

Recombinant hydroxynitrile lyase: high level expression in Pichia pastoris

Lanfranchi, E., Dorota Katarzyna, P., Kerstin, S., Schwab, H., Glieder, A., Rolan, W. & Margit, W., 2013.

Research output: Contribution to conferencePosterResearch

Surface engineering of a cutinase from Thermobifida cellulosilytica for improved polyester hydrolysis

Herrero Acero, E., Ribitsch, D., Dellacher, A., Zitzenbacher, S., Marold, A., Steinkellner, G., Gruber, K., Schwab, H. & Gübitz, G., 2013, In : Biotechnology and Bioengineering. 110, 10, p. 2581–2590

Research output: Contribution to journalArticleResearchpeer-review

Terpenoid production in yeasts

Wriessnegger, T., Emmerstorfer, A., Müller, M., Kaluzna, I., Schwab, H. & Pichler, H., 9 Oct 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Terpenoid production in yeasts

Wriessnegger, T., Emmerstorfer, A., Müller, M., Kaluzna, I., Schwab, H. & Pichler, H., 2013, Book of abstracts. Zagreb: Recedo d.o.o., Zagreb, p. 26-26

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

The natural way to a natural product - microbial production of 3-hydroxytyrosol

Napora, K., Sonavane, M. N., Plewka, J., Pomorska, D. K., Robins, K., Osorio-Lozada, A., Steiner, K., Schwab, H. & Winkler, M., 23 Sep 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

The role of surface amino acids on cutinases is a key to tune hydrolysis of polyethylene terephthalate

Herrero Acero, E., Ribitsch, D., Marold, A., Greimel, K. J., Steinkellner, G., Gruber, K., Schwab, H. & Gübitz, G., 21 Apr 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

2012

(+)-Nootkatone production in yeasts

Wriessnegger, T., Augustin, P., Emmerstorfer, A., Müller, M., Kaluzna, I., Macheroux, P., Schwab, H. & Pichler, H., 2012.

Research output: Contribution to conferencePosterResearch

(R)-Selective amination

Schurmann, M., Peeters, W. P. H., Smeets, N. H. J., Schwab, H., Steiner, K., Fesko, K. & Strohmeier, G., 19 Jan 2012, IPC No. C12N1/14; C12N1/20; C12N15/54; C12N9/10; C12P13/00, Patent No. WO2012007548, Priority date 14 Jul 2010, Priority No. EP20100169573 20100714

Research output: PatentResearch

Amination
Transaminases
Patents and inventions
Ketones
Microorganisms

Alternative Cofactors for AdoMet-dependent Methyltransferases

Gruber, M., Stecher, H., Tengg, M., Remler, P. & Schwab, H., 2012.

Research output: Contribution to conferencePosterResearch

A New Esterase from Thermobifida halotolerans Hydrolyses Polyethylene Terephthalate (PET) and Polylactic Acid (PLA)

Ribitsch, D., Herrero Acero, E., Greimel, K. J., Dellacher, A., Zitzenbacher, S., Marold, A., Diaz Rodriguez, R., Steinkellner, G., Gruber, K., Schwab, H. & Gübitz, G., 2012, In : e-Polymers. 4, 1, p. 617-629

Research output: Contribution to journalArticleResearchpeer-review

A novel multifunctional sialyltransferase PdST from Pasteurella dagmatis

Schmoelzer, K., Kokot, D., Czabany, T., Luley, C., Ribitsch, D., Zitzenbacher, S., Augustin, P. A., Lyskowski, A. F., Nidetzky, B. & Schwab, H., 2 Jul 2012.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Characterisation of bacterial hydroxynitrile lyases

Steiner, K., Hajnal, I., Wiedner, R., Lyskowski, A. F., Gruber, C., Steinkellner, G., Gruber, K., Hanefeld, U. & Schwab, H., 17 Sep 2012.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Characterisation of bacterial hydroxynitrile lyases with a cupin fold

Steiner, K., Hajnal, I., Wiedner, R., Lyskowski, A. F., Gruber, C., Steinkellner, G., Gruber, K., Hanefeld, U. & Schwab, H., 2012.

Research output: Contribution to conferencePosterResearch

Characterization of a new cutinase from Thermobifida alba regarding PET-surface hydrolysis

Ribitsch, D., Herrero Acero, E., Greimel, K. J., Eiteljörg, I., Trotscha, E., Freddi, G., Schwab, H. & Gübitz, G., 2012, In : Biocatalysis and Biotransformation. 30, 1, p. 2-9

Research output: Contribution to journalArticleResearchpeer-review

Characterization of two bacterial hydroxynitrile lyases with high similarity to cupin superfamily proteins

Hussain, Z., Wiedner, R., Steiner, K., Hajek, T., Avi, M., Hecher, B., Sessitsch, A. & Schwab, H., 2012, In : Applied and Environmental Microbiology. p. 2053-2055

Research output: Contribution to journalArticleResearchpeer-review

Crystallisation of the novel S-adenosyl-L-methionine dependent C-methyltransferase CouO from Streptomyces rishiriensis and preliminary diffraction data analysis. Acta Crystallogr., Sect. F: Struct. Biol. Cryst. Commun.

Lyskowski, A., Tengg, M., Steinkellner, G., Schwab, H., Gruber, M. & Gruber, K., 2012, In : Acta Crystallographica / F. F68, p. 698-700

Research output: Contribution to journalArticleResearchpeer-review

Crystallization of a novel metal-containing cupin from Acidobacterium sp. and preliminary diffraction data analysis

Steiner, K., Lyskowski, A. F., Hajnal, I., Steinkellner, G., Schwab, H. & Gruber, K., 2012, In : Acta Crystallographica / F. 68, 4, p. 451-454

Research output: Contribution to journalArticleResearchpeer-review

Engineering of the yeast Pichia pastoris for high-level production of (+)-nootkatone

Wriessnegger, T., Augustin, P., Müller, M., Kaluzna, I., Schwab, H. & Pichler, H., 2012.

Research output: Contribution to conferencePosterResearch

Enzymatic functionalization of synthetic polymers via double enzymatic reaction

Herrero Acero, E., Ribitsch, D., Diaz Rodriguez, R., Greimel, K. J., Marold, A., Schwab, H. & Gübitz, G., 2012.

Research output: Contribution to conferencePosterResearch

Enzymatic functionalization of synthetic polymers via two-step enzymatic functionalisation

Herrero Acero, E., Ribitsch, D., Diaz Rodriguez, R., Greimel, K. J., Marold, A., Schwab, H. & Gübitz, G., 10 Apr 2012.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Expression of mammalian glycosyltransferases in yeast

Ribitsch, D., Zitzenbacher, S., Augustin, P. A., Schmoelzer, K., Czabany, T., Luley, C., Nidetzky, B. & Schwab, H., 2012.

Research output: Contribution to conferencePosterResearch