Harald Pichler

Assoc.Prof. Dipl.-Ing. Dr.techn.

19962019
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Research Output 1996 2019

2019

Membrane protein production in yeast: Modification of yeast membranes for human membrane protein production

Emmerstorfer-Augustin, A., Wriessnegger, T., Hirz, M., Zellnig, G. & Pichler, H., 9 Feb 2019, Recombinant Protein Production in Yeast: Methods and Protocols. Springer, (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Recombinant lipoxygenases (LOX) and hydroperoxide lyases (HPL) for the synthesis of green leaf volatiles

Stolterfoht, H., Rinnofner, C., Winkler, M. & Pichler, H., 8 Oct 2019, (Accepted/In press) In : Journal of agricultural and food chemistry. 59 p.

Research output: Contribution to journalReview articleResearchpeer-review

Lipoxygenases
lyases
hydroperoxides
lipoxygenase
synthesis

Recombinant lipoxygenases and hydroperoxide lyases for the synthesis of green leaf volatiles

Stolterfoht, H., Rinnofner, C., Winkler, M. & Pichler, H., 2019, (Accepted/In press) In : Journal of agricultural and food chemistry.

Research output: Contribution to journalReview articleResearchpeer-review

Valorization of Fatty Acids by Pichia pastoris: A Fresh Approach for Green Leaf Volatile Synthesis

Hashem, C., Steinberger, S., Stolterfoht, H., Rinnofner, C., Winkler, M. & Pichler, H., 12 Nov 2019.

Research output: Contribution to conferencePosterResearch

2018

Modification of Membrane Lipid Compositions in single-celled organisms–from Basics to Applications

Pichler, H. & Emmerstorfer-Augustin, A., 13 Sep 2018, In : Methods. 147, p. 50 - 65 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

On the current role of hydratases in biocatalysis

Engleder, M. & Pichler, H., 15 Jul 2018, In : Applied Microbiology and Biotechnology. 102, p. 5841-5858

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Perdeuteration of cholesterol for neutron scattering applicatioins using recombinant Pichia pastoris

Mouline, M., Strohmeier, G., Hirz, M., Thompson, K., Rennie, A., Campbell, R. A., Pichler, H., Maric, S., Forsyth, T. & Haertlein, M., 5 Feb 2018, In : Chemistry and Physics of Lipids. 212, p. 80-87

Research output: Contribution to journalArticleResearchpeer-review

Recombinant expression, purification and biochemical characterization of kievitone hydratase from Nectria haematococca

Engleder, M., Horvat, M., Emmerstorfer-Augustin, A., Wriessnegger, T., Gabriel, S., Strohmeier, G., Weber, H., Müller, M., Kaluzna, I., Mink, D., Schürmann, M. & Pichler, H., 8 Feb 2018, In : PLoS ONE.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

The Impact of Deuteration on Natural and Synthetic Lipids: a Neutron Diffraction Study

Luchini, A., Delhom, R., Demé, B., Laux, V., Mouline, M., Haertlein, M., Pichler, H., Strohmeier, G., Wacklin, H. & Fragneto, G., 1 Aug 2018, In : Colloids and Surfaces / B. p. 126 - 133

Research output: Contribution to journalArticleResearchpeer-review

Whole-cell (+)-ambrein production in the yeast Pichia pastoris

Moser, S., Strohmeier, G., Leitner, E., Plocek, T. J., Vanhessche, K. & Pichler, H., Dec 2018, In : Metabolic Engineering Communications. 7, 9 p., e00077.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Whole-cell (+)-ambrein production in the yeast Pichia pastoris

Moser, S., Strohmeier, G. A., Leitner, E., Plocek, T. J., Vanhessche, K. & Pichler, H., 26 Jun 2018.

Research output: Contribution to conferencePosterResearch

2017

Application of hydratases for flavor and fragrance synthesis

Engleder, M., Pavkov-Keller, T., Emmerstorfer, A., Hromic, A., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Daniel, M., Schürmann, M., Wallner, S., Macheroux, P., Pichler, H. & Gruber, K., 14 Nov 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Application of hydratases for flavour and fragrance synthesis

Engleder, M., Pavkov-Keller, T., Emmerstorfer, A., Altijana, H., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Mink, D., Schürmann, M., Wallner, S., Macheroux, P., Gruber, K. & Pichler, H., 20 Sep 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Carboxylic Acid Reductase mediated Biotransformations

Schwendenwein, D., Fiume, G., Pichler, H. & Winkler, M., 11 Jul 2017.

Research output: Contribution to conferencePosterResearch

Enhancing (+)-nootkatone production in P. pastoris and S. cerevisiae through CYP450-mediated conversions

Moser, S., Wriessnegger, T., Emmerstorfer-Augustin, A., Wimmer-Teubenbacher, M., Leitner, E., Engleder, M., Müller, M., Daniel, M., Schurmann, M. & Pichler, H., 14 Nov 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Enhancing (+)-nootkatone production in Pichia pastoris and Saccharomyces cerevisiae through cytochrome P450-mediated conversions

Moser, S., Wriessnegger, T., Emmerstorfer-Augustin, A., Wimmer-Teubenbacher, M., Leitner, E., Engleder, M., Müller, M., Schürmann, M., Pichler, H. & Daniel, M., 20 Sep 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Enhancing cytochrome P450-mediated conversions in P. pastoris

Moser, S., Wriessnegger, T., Emmerstorfer-Augustin, A., Leitner, E., Müller, M., Kaluzna, I., Schürmann, M., Daniel, M. & Pichler, H., 24 Apr 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Identification of key residues in Neurospora crassa Carboxylate reductase (CAR)

Stolterfoht, H., Schwendenwein, D., Rudroff, F., Pichler, H. & Winkler, M., 15 Nov 2017.

Research output: Contribution to conferencePosterResearch

Identification of key residues in Neurospora crassa Carboxylate reductase (CAR)

Stolterfoht, H., Schwendenwein, D., Rudroff, F., Pichler, H. & Winkler, M., 11 Jul 2017.

Research output: Contribution to conferencePosterResearch

Localization of Cholesterol within Supported Lipid Bilayers Made of a Natural Extract of Tailor-Deuterated Phosphatidylcholine

Waldie, S., Lind, T. K., Browning, K., Mouline, M., Haertlein, M., Forsyth, T., Luchini, A., Strohmeier, G., Pichler, H., Maric, S. & Cárdenas, M., 27 Dec 2017, In : Langmuir. 34, 1, p. 472-479 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Lipid bilayers
Cholesterol
cholesterol
Lipid Bilayers
Phosphatidylcholines

Production of sterols in modified yeasts

Hohmann, H-P., Leber, R., Lehmann, M., Odar, C., Petschacher, B. & Pichler, H., 29 Jun 2017, IPC No. C12P/33/00, Patent No. PCT/EP2016/, Priority date 23 Dec 2015, Priority No. 01908/15

Research output: PatentResearch

Structure-based reaction mechanism of oleate hydratase from Elizabethkingia meningoseptica

Engleder, M., Pavkov-Keller, T., Emmerstorfer-Augustin, A., Hromic, A., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Daniel, M., Martin, S., Wallner, S., Macheroux, P., Gruber, K. & Pichler, H., 23 Apr 2017.

Research output: Contribution to conferencePosterResearchpeer-review

Hydro-Lyases
Oleic Acid
Hydration
Flavin-Adenine Dinucleotide
Carbon
2016

Enhancing cytochrome P450-mediated conversions in P. pastoris

Moser, S., Wriessnegger, T., Emmerstorfer, A., Leitner, E., Müller, M., Kaluzna, I., Schurmann, M., Daniel, M. & Pichler, H., 15 Nov 2016.

Research output: Contribution to conferencePosterResearchpeer-review

Enhancing cytochrome P450-mediated conversions in P. pastoris through RAD52 over-expression and optimizing the cultivation conditions

Wriessnegger, T., Moser, S., Emmerstorfer-Augustin, A., Leitner, E., Müller, M., Kaluzna, I., Schürmann, M., Daniel, M. & Pichler, H., 8 Mar 2016, In : Fungal genetics and biology. 89, p. 114-125

Research output: Contribution to journalArticleResearchpeer-review

Metabolic engineering of Pichia pastoris for ginsenoside production

Emmerstorfer-Augustin, A., Odar, C., Wriessnegger, T. & Pichler, H., 15 Nov 2016.

Research output: Contribution to conferencePosterResearchpeer-review

Oleate hydratases - structure function relationship and application

Pichler, H., 1 Oct 2016.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Oleate hydratase - structure function relationships and application

Pichler, H., 1 Oct 2016, Power of microbes in industry and environment: Book of abstracts. Mrsa, V., Teparic, R. & Kifer, D. (eds.). Zagreb: Recedo d.o.o., Zagreb, p. 33 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearch

Optimization of Peptide Secretion in P. pastoris

Hirz, M., Odar, C., Leithold, C., Pichler, H. & Schwab, H., 5 Feb 2016.

Research output: Contribution to conferencePosterResearchpeer-review

Production of aromatic plant terpenoids in recombinant baker´s yeast

Emmerstorfer, A. & Pichler, H., 2016, Biotechnology of Plant Secondary Metabolism. 1 ed. New York: Springer, p. 79-89 (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingChapterResearch

Screening for improved isoprenoid biosynthesis in microorganisms

Emmerstorfer, A., Moser, S. & Pichler, H., 2016, In : Journal of Biotechnology. 235, p. 112–120

Research output: Contribution to journalArticleResearchpeer-review

Sterol and terpenoid engineering in yeasts

Pichler, H., 10 May 2016.

Research output: Contribution to conference(Old data) Lecture or PresentationResearchpeer-review

Sterol-modified P. pastoris: Membrane Protein Expression and Cell Physiology

Hirz, M., Richter, G., Wriessnegger, T., Zellnig, G., Leitner, E. & Pichler, H., 11 Jul 2016.

Research output: Contribution to conferencePosterResearchpeer-review

Structure-based reaction mechanism of oleate hydratase from Elizabethkingia meningoseptica

Engleder, M., Pavkov-Keller, T., Emmerstorfer-Augustin, A., Altijana, H., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Daniel, M., Schurmann, M., Wallner, S., Macheroux, P., Gruber, K. & Pichler, H., 15 Nov 2016.

Research output: Contribution to conferencePosterResearchpeer-review

2015

APPLYING CYTOCHROME P450 ENZYMES FOR FLAVOUR&FRAGRANCE BIOSYNTHESIS IN YEASTS

Wriessnegger, T., Emmerstorfer, A., Moser, S., Wimmer-Teubenbacher, M., Augustin, P. A., Engleder, M., Leitner, E., Zellnig, G., Müller, M., Kaluzna, I., Mink, D., Schürmann, M., Schwab, H. & Pichler, H., 26 Jul 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

ON THE REACTION MECHANISM OF THE ELIZABETHKINGIA MENINGOSEPTICA OLEATE HYDRATASE

Engleder, M., Pavkov-Keller, T., Emmerstorfer, A., Hromic, A., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Mink, D., Schürmann, M., Wallner, S., Macheroux, P., Gruber, K. & Pichler, H., 2015.

Research output: Contribution to conferencePosterResearch

Over-expression of ICE2 stabilizes cytochrome P450 reductase levels in Saccharomyces cerevisiae and Pichia pastoris

Emmerstorfer, A., Wimmer-Teubenbacher, M., Wriessnegger, T., Leitner, E., Müller, M., Kaluzna, I., Schürmann, M., Mink, D., Zellnig, G., Schwab, H. & Pichler, H., 2015, In : Biotechnology Journal. 10, p. 623-635

Research output: Contribution to journalArticleResearchpeer-review

Sphingolipids regulate telomere clustering by affecting transcriptional levels of genes involved in telomere homeostasis

Ikeda, A., Muneoka, T., Murakami, S., Hirota, A., Yabuki, Y., Karashima, T., Nakazono, K., Tsuruno, M., Pichler, H., Shirahige, K., Kodama, Y., Shimamoto, T., Mizuta, K. & Funato, K., 2015, In : Journal of cell science. 128, p. 2454-2467

Research output: Contribution to journalArticleResearchpeer-review

Stabilization of cytochrome P450 reductase

Emmerstorfer, A., Wriessnegger, T., Wimmer-Teubenbacher, M., Pichler, H., Müller, M., Kaluzna, I. & Schurmann, M., 29 Oct 2015, Patent No. WO 2015/162305 A1

Research output: PatentResearch

Structure-based mechanism of oleate hydratase from Elizabethkingia meningoseptica

Engleder, M., Pavkov-Keller, T., Emmerstorfer, A., Altijana, H., Schrempf, S., Steinkellner, G., Wriessnegger, T., Leitner, E., Strohmeier, G., Kaluzna, I., Daniel, M., Martin, S., Wallner, S., Macheroux, P., Gruber, K. & Pichler, H., 2015, In : ChemBioChem. 16, p. 1730-1734

Research output: Contribution to journalArticleResearchpeer-review

2014

(+)-Nootkatone production in yeasts

Wriessnegger, T., Emmerstorfer, A., Müller, M., Kaluzna, I., Schwab, H. & Pichler, H., 27 May 2014.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

(+)-Nootkatone production in yeasts

Wriessnegger, T., Emmerstorfer, A., Augustin, P. A., Engleder, M., Müller, M., Kaluzna, I., Schwab, H. & Pichler, H., 2014.

Research output: Contribution to conferencePosterResearch

Characterizing microbial and mammalian acyl-transferases in a cholesterol-producing yeast strain

Albrecht, B., Petschacher, B., Stolterfoht, H., Littringer, K., Lehmann, M., Hohmann, H-P. & Pichler, H., 15 Sep 2014.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Characterizing the Sterol Specificity of Microbial and Mammalian Acyltransferases

Stolterfoht, H., Petschacher, B., Littringer, K., Ungerböck, F., Odar, C., Lehmann, M., Hohmann, H-P. & Pichler, H., 2014.

Research output: Contribution to conferencePosterResearch

Heterologous expression of membrane proteins in engineered yeasts - (+)-nootkatone production in yeasts

Wriessnegger, T., Emmerstorfer, A., Hirz, M., Augustin, P. A., Engleder, M., Richter, G. & Pichler, H., 4 Jun 2014.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Improving heterologous cytochrome P450 functionality in Saccharomyces cerevisiae and Pichia pastoris

Emmerstorfer, A., Wimmer-Teubenbacher, M., Wriessnegger, T., Müller, M., Kaluzna, I., Schürmann, M. & Pichler, H., 2014.

Research output: Contribution to conferencePosterResearch

Overexpression of membrane proteins from higher eukaryotes in yeasts

Emmerstorfer, A., Wriessnegger, T., Hirz, M. & Pichler, H., 2014, In : Applied Microbiology and Biotechnology. 98, 18, p. 7671-7698

Research output: Contribution to journalArticleResearchpeer-review

Pichia pastoris Aft1 - a novel transcription factor, enhancing recombinant protein secretion

Ruth, C., Buchetics, M., Vidimce, V., Kotz, D., Naschberger, S., Mattanovich, D., Pichler, H. & Gasser, B., 2014, In : Microbial cell factories . 13, p. 120-120

Research output: Contribution to journalArticleResearchpeer-review