Gerhard Thallinger

Dipl.-Ing. Dr.techn.

20002020
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Research Output 2000 2018

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2018

A concise review of significantly modified serological biomarkers in giant cell arteritis, as detected by different methods

Burja, B., Kuret, T., Sodin-Semrl, S., Lakota, K., Rotar, Ž., Ješe, R., Mrak-Poljšak, K., Žigon, P., Thallinger, G. G., Feichtinger, J., Čučnik, S., Tomšič, M., Praprotnik, S. & Hočevar, A., 1 Feb 2018, In : Autoimmunity Reviews. 17, 2, p. 188-194

Research output: Contribution to journalArticleResearchpeer-review

Giant Cell Arteritis
Biomarkers
Arteries
Systemic Vasculitis
Acute-Phase Proteins

Comparison and evaluation of integrative methods for the analysis of multilevel omics data: a study based on simulated and experimental cancer data

Pucher, B. M., Zeleznik, O. A. & Thallinger, G. G., 23 Apr 2018, In : Briefings in Bioinformatics.

Research output: Contribution to journalArticleResearchpeer-review

Multilevel Analysis
Microarrays
Factorization
Data mining
Neoplasms

Comparison of tear proteome in allergic rhinoconjunctivitis patients and controls with respect to pollen season

Tomazic, P. V., Liesinger, L., Pucher, B., Thallinger, G. G., Leitner, A., Spoerk, S., Gerstenberger, C., Lang-Loidolt, D. & Birner-Gruenberger, R., Jul 2018, In : Allergy. 73, 7, p. 1541-1543

Research output: Contribution to journalArticleResearchpeer-review

Cytoplasmic location of NR4A1 in aggressive lymphomas is associated with a favourable cancer specific survival

Fechter, K., Feichtinger, J., Prochazka, K., Unterluggauer, J. J., Pansy, K., Steinbauer, E., Pichler, M., Haybaeck, J., Prokesch, A., Greinix, H. T., Beham-Schmid, C., Neumeister, P., Thallinger, G. G. & Deutsch, A. J. A., 28 Sep 2018, In : Scientific reports. 8, 1, 14528.

Research output: Contribution to journalArticleResearchpeer-review

Lymphoma
Survival
Nuclear Receptor Subfamily 4, Group A, Member 1
Neoplasms
Germinal Center

Deletion of Adipose Triglyceride Lipase Links Triacylglycerol Accumulation to a More-Aggressive Phenotype in A549 Lung Carcinoma Cells

Tomin, T., Fritz, K., Gindlhuber, J., Waldherr, L., Pucher, B., Thallinger, G. G., Nomura, D. K., Schittmayer, M. & Birner-Gruenberger, R., 6 Apr 2018, In : Journal of proteome research. 17, 4, p. 1415-1425

Research output: Contribution to journalArticleResearchpeer-review

Lipase
Triglycerides
Cells
Carcinoma
Phenotype

Gene and miRNA expression in giant cell arteritis-a concise systematic review of significantly modified studies

Kuret, T., Burja, B., Feichtinger, J., Thallinger, G. G., Frank-Bertoncelj, M., Lakota, K., Žigon, P., Sodin-Semrl, S., Čučnik, S., Tomšič, M. & Hočevar, A., 1 Aug 2018, In : Clinical Rheumatology.

Research output: Contribution to journalArticleResearchpeer-review

Giant Cell Arteritis
MicroRNAs
Gene Expression
Arteries
Inflammation

Methanol independent induction in Pichia pastoris by simple derepressed overexpression of single transcription factors

Vogl, T., Sturmberger, L., Fauland, P. C., Hyden, P., Fischer, J. E., Schmid, C., Thallinger, G. G., Geier, M. & Glieder, A., 1 Apr 2018, In : Biotechnology and Bioengineering. 115, 4, p. 1037-1050

Research output: Contribution to journalArticleResearchpeer-review

Transcription factors
Pichia
Methanol
Transcription Factors
Carbon

Myristic acid induces proteomic and secretomic changes associated with steatosis, cytoskeleton remodeling, endoplasmic reticulum stress, protein turnover and exosome release in HepG2 cells

Speziali, G., Liesinger, L., Gindlhuber, J., Leopold, C., Pucher, B., Brandi, J., Castagna, A., Tomin, T., Krenn, P., Thallinger, G. G., Olivieri, O., Martinelli, N., Kratky, D., Schittmayer, M., Birner-Gruenberger, R. & Cecconi, D., 15 Jun 2018, In : Journal of proteomics. 181, p. 118-130

Research output: Contribution to journalArticleResearchpeer-review

Exosomes
Endoplasmic Reticulum Stress
Hep G2 Cells
Myristic Acid
Heat-Shock Proteins

Phylogenomics uncovers early hybridization and adaptive loci shaping the radiation of Lake Tanganyika cichlid fishes

Irisarri, I., Singh, P., Koblmüller, S., Torres-Dowdall, J., Henning, F., Franchini, P., Fischer, C., Lemmon, A. R., Lemmon, E. M., Thallinger, G. G., Sturmbauer, C. & Meyer, A., 8 Aug 2018, In : Nature Communications. 9, 1, 3159.

Research output: Contribution to journalArticleResearchpeer-review

Cichlids
Tanzania
fishes
loci
Lakes

The mitochondrial genome of the oribatid mite Paraleius leontonychus: new insights into tRNA evolution and phylogenetic relationships in acariform mites

Schäffer, S., Koblmüller, S., Klymiuk, I. & Thallinger, G. G., 15 May 2018, In : Scientific reports. 8, 1, 7558.

Research output: Contribution to journalArticleResearchpeer-review

Mitochondrial Genome
Mites
Transfer RNA
RNA, Transfer, Gly
RNA, Transfer, Tyr

Utility of serological biomarkers for giant cell arteritis in a large cohort of treatment-naïve patients

Burja, B., Feichtinger, J., Lakota, K., Thallinger, G. G., Sodin-Semrl, S., Kuret, T., Rotar, Ž., Ješe, R., Žigon, P., Čučnik, S., Mali, P., Praprotnik, S., Tomšič, M. & Hočevar, A., 24 Aug 2018, In : Clinical Rheumatology.

Research output: Contribution to journalArticleResearchpeer-review

Giant Cell Arteritis
Biomarkers
Blood Donors
Matrix Metalloproteinases
Therapeutics
2017

Critical Issues in Mycobiota Analysis

Halwachs, B., Madhusudhan, N., Krause, R., Nilsson, R. H., Moissl-Eichinger, C., Högenauer, C., Thallinger, G. G. & Gorkiewicz, G., 2017, In : Frontiers in Microbiology . 8, 180.

Research output: Contribution to journalArticleResearchpeer-review

Microbiota
Computational Biology
Fungal Genes
rRNA Genes
Computer Simulation

Deciphering lipid structures based on platform-independent decision rules

Hartler, J., Triebl, A., Ziegl, A., Trötzmüller, M., Rechberger, G. N., Zeleznik, O. A., Zierler, K. A., Torta, F., Cazenave-Gassiot, A., Wenk, M. R., Fauland, A., Wheelock, C. E., Armando, A. M., Quehenberger, O., Zhang, Q., Wakelam, M. JO., Haemmerle, G., Spener, F., Köfeler, H. C. & Thallinger, G. G., 1 Dec 2017, In : Nature methods. 14, 12, p. 1171-1174

Research output: Contribution to journalArticleResearchpeer-review

Lipids
Mass spectrometry
Software reliability
Tandem Mass Spectrometry
Chromatography
mandelonitrile lyase
Enzymes
Biocatalysis
Ferns
Crystallography

Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

Lanfranchi, E., Pavkov-Keller, T., Koehler, E-M., Diepold, M., Steiner, K., Darnhofer, B., Hartler, J., Van Den Bergh, T., Joosten, H-J., Gruber-Khadjawi, M., Thallinger, G. G., Birner-Gruenberger, R., Gruber, K., Winkler, M. & Glieder, A., 10 May 2017, In : Scientific reports. 7, 46738.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
mandelonitrile lyase
Enzymes
Biocatalysis
Ferns
Crystallography

Erratum: Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily

Lanfranchi, E., Pavkov-Keller, T., Koehler, E-M., Diepold, M., Steiner, K., Darnhofer, B., Hartler, J., Bergh, T. V. D., Joosten, H-J., Gruber-Khadjawi, M., Thallinger, G. G., Birner-Gruenberger, R., Gruber, K., Winkler, M. & Glieder, A., 26 May 2017, In : Scientific reports. 7, 46834.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
mandelonitrile lyase
Enzymes

Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis

Planells-Palop, V., Hazazi, A., Feichtinger, J., Jezkova, J., Thallinger, G., Alsiwiehri, N. O., Almutairi, M., Parry, L., Wakeman, J. A. & McFarlane, R. J., 26 Apr 2017, In : Molecular Cancer. 16, 1, 84.

Research output: Contribution to journalArticleResearchpeer-review

Germ Cells
Stem Cells
Cell Proliferation
Genes
Neoplasms

MetExtract II: A Software Suite for Stable Isotope-Assisted Untargeted Metabolomics

Bueschl, C., Kluger, B., Neumann, N. K. N., Doppler, M., Maschietto, V., Thallinger, G. G., Meng-Reiterer, J., Krska, R. & Schuhmacher, R., 5 Sep 2017, In : Analytical Chemistry. 89, 17, p. 9518-9526

Research output: Contribution to journalArticleResearchpeer-review

Metabolites
Isotopes
Mass spectrometry
Liquid chromatography
Labeling

NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes

Deutsch, A. J. A., Rinner, B., Pichler, M., Prochazka, K., Pansy, K., Bischof, M., Fechter, K., Hatzl, S., Feichtinger, J., Wenzl, K., Frisch, M-T., Stiegelbauer, V., Prokesch, A., Krogsdam, A., Sill, H., Thallinger, G. G., Greinix, H. T., Wang, C., Beham-Schmid, C. & Neumeister, P., 1 May 2017, In : Cancer Research. 77, 9, p. 2375-2386

Research output: Contribution to journalArticleResearchpeer-review

Lymphoma
Genes
Neoplasms
Nuclear Receptor Subfamily 4, Group A, Member 1
Puma

The Human Gastric Microbiome Is Predicated upon Infection with Helicobacter pylori

Klymiuk, I., Bilgilier, C., Stadlmann, A., Thannesberger, J., Kastner, M-T., Högenauer, C., Püspök, A., Biowski-Frotz, S., Schrutka-Kölbl, C., Thallinger, G. G. & Steininger, C., 14 Dec 2017, In : Frontiers in Microbiology . 8, 2508.

Research output: Contribution to journalArticleResearchpeer-review

Microbiota
Helicobacter pylori
Stomach
Infection
Helicobacter Infections
2016

A Toolbox of Diverse Promoters Related to Methanol Utilization: Functionally Verified Parts for Heterologous Pathway Expression in Pichia pastoris

Vogl, T., Sturmberger, L., Kickenweiz, T., Wasmayer, R., Schmid, C., Hatzl, A-M., Gerstmann, M. A., Pitzer, J., Wagner, M., Thallinger, G. G., Geier, M. & Glieder, A., 19 Feb 2016, In : ACS Synthetic Biology . 5, 2, p. 172-86 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Methanol
alcohol oxidase
Genes
Biosynthetic Pathways

Characterisation of Candida within the Mycobiome/Microbiome of the Lower Respiratory Tract of ICU Patients

Krause, R., Halwachs, B., Thallinger, G., Klymiuk, I., Gorkiewicz, G., Hoenigl, M., Prattes, J., Valentin, T., Heidrich, K., Buzina, W., Salzer, H. J. F., Rabensteiner, J., Prüller, F., Raggam, R. B., Meinitzer, A., Moissl-Eichinger, C., Högenauer, C., Quehenberger, F., Kashofer, K. & Zollner-Schwetz, I., 20 May 2016, In : PLoS ONE. 11, 5, p. e0155033 e0155033.

Research output: Contribution to journalArticleResearchpeer-review

Intensive care units
Candida
Microbiota
respiratory system
Respiratory System

Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time

Feichtinger, J., Hernández, I., Fischer, C., Hanscho, M., Auer, N., Hackl, M., Jadhav, V., Baumann, M., Krempl, P. M., Schmidl, C., Farlik, M., Schuster, M., Merkel, A., Sommer, A., Heath, S., Rico, D., Bock, C., Thallinger, G. G. & Borth, N., Oct 2016, In : Biotechnology and Bioengineering. 113, 10, p. 2241-53 13 p.

Research output: Contribution to journalArticleResearchpeer-review

CHO Cells
Genes
Genome
DNA Methylation
Pressure

Curation of the genome annotation of Pichia pastoris (Komagataella phaffii) CBS7435 from gene level to protein function

Valli, M., Tatto, N. E., Peymann, A., Gruber, C., Landes, N., Ekker, H., Thallinger, G. G., Mattanovich, D., Gasser, B. & Graf, A. B., Sep 2016, In : FEMS yeast research. 16, 6, fow051.

Research output: Contribution to journalArticleResearchpeer-review

Pichia
Open Reading Frames
Genome
Molecular Sequence Annotation
Genes

Dimension reduction techniques for the integrative analysis of multi-omics data

Meng, C., Zeleznik, O. A., Thallinger, G. G., Küster, B., Gholami, A. M. & Culhane, A. C., Jul 2016, In : Briefings in Bioinformatics. 17, 4, p. 628-41 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Data integration
Biological systems
Throughput
Proteomics
Technology

Inferring expressed genes by whole-genome sequencing of plasma DNA

Ulz, P., Thallinger, G. G., Auer, M., Graf, R., Kashofer, K., Jahn, S. W., Abete, L., Pristauz, G., Petru, E., Geigl, J. B., Heitzer, E. & Speicher, M. R., Oct 2016, In : Nature genetics. 48, 10, p. 1273-8 6 p.

Research output: Contribution to journalArticleResearchpeer-review

DNA Sequence Analysis
Genome
DNA
Nucleosomes
Genes

Molecular profiling of phagocytic immune cells in Anopheles gambiae reveals integral roles for hemocytes in mosquito innate immunity

Smith, R. C., King, J. G., Tao, D., Zeleznik, O. A., Brando, C., Thallinger, G. G. & Dinglasan, R. R., 13 Sep 2016, In : Molecular & cellular proteomics.

Research output: Contribution to journalArticleResearchpeer-review

Anopheles gambiae
Hemocytes
Phagocytes
Culicidae
Innate Immunity

Translin and Trax differentially regulate telomere-associated transcript homeostasis

Gomez-Escobar, N., Almobadel, N., Alzahrani, O., Feichtinger, J., Planells-Palop, V., Alshehri, Z., Thallinger, G. G., Wakeman, J. A. & McFarlane, R. J., 7 Jun 2016, In : OncoTarget . 7, 23, p. 33809-20 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Telomere
Homeostasis
Schizosaccharomyces pombe Proteins
Biological Phenomena
Heterochromatin
2015

ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6

Eichmann, T., Grumet, L., Taschler, U., Hartler, J., Heier, C., Woblistin, A., Pajed, L., Kollroser, M., Rechberger, G., Thallinger, G. G., Zechner, R., Haemmerle, G., Zimmermann, R. & Lass, A., 2015, In : Journal of lipid research. p. 1972-1984

Research output: Contribution to journalArticleResearchpeer-review

miR-199a and miR-497 Are Associated with Better Overall Survival due to Increased Chemosensitivity in Diffuse Large B-Cell Lymphoma Patients.

Troppan, K., Wenzl, K., Pichler, M., Pursche, B., Schwarzenbacher, D., Feichtinger, J., Thallinger, G., Beham-Schmid, C., Neumeister, P. & Deutsch, A. J., 2015, In : International Journal of Molecular Sciences . 16, 8, p. 18077-18095

Research output: Contribution to journalArticleResearchpeer-review

Restoration of female fertility in Trichoderma reesei QM6a provides the basis for inbreeding

Linke, R., Thallinger, G., Haarmann, T., Eidner, J., Schreiter, M., Lorenz, P., Seiboth, B. & Kubicek, C. P., 2015, In : Biotechnology for Biofuels . 8, p. 155-155

Research output: Contribution to journalArticleResearchpeer-review

2014

A novel stable isotope labelling assisted workflow for improved untargeted LC-HRMS based metabolomics research

Bueschl, C., Kluger, B., Lemmens, M., Adam, G., Wiesberger, G., Maschietto, V., Marocco, A., Strauss, J., Bödi, S., Thallinger, G., Krska, R. & Schuhmacher, R., 2014, In : Metabolomics. 10, 4, p. 754-769

Research output: Contribution to journalArticleResearchpeer-review

A physicians' wish list for the clinical application of intestinal metagenomics

Klymiuk, I., Högenauer, C., Halwachs, B., Thallinger, G., Fricke, F. W. & Steininger, C., 2014, In : PLoS medicine. 11, 4, p. e1001627-e1001627

Research output: Contribution to journalArticleResearchpeer-review

Assessment of lipidomic species in hepatocyte lipid droplets from stressed mouse models

Hartler, J., Köfeler, H., Trötzmüller, M., Thallinger, G. & Spener, F., 2014, In : Scientific Data . 1, 140051, p. 1-12

Research output: Contribution to journalArticleResearchpeer-review

Comparative Genome Analysis of Campylobacter fetus Subspecies Revealed Horizontally Acquired Genetic Elements Important for Virulence and Niche Specificity

Kienesberger, S., Sprenger, H., Wolfgruber, S., Halwachs, B., Thallinger, G., Perez-Perez, G. I., Blaser, M. J., Zechner, E. & Gorkiewicz, G., 2014, In : PLoS ONE. 9, 1, p. e85491-e85491

Research output: Contribution to journalArticleResearchpeer-review

Enhanced whole genome sequence and annotation of Clostridium stercorarium DSM8532T using RNA-seq transcriptomics and high-throughput proteomics

Schellenberg, J. J., Verbeke, T. J., McQueen, P., Krokhin, O. V., Zhang, X., Alvare, G., Fristensky, B., Thallinger, G., Henrissat, B., Wilkins, J. A., Levin, D. B. & Sparling, R., 2014, In : BMC Genomics . 15, 1, p. 567-567

Research output: Contribution to journalArticleResearchpeer-review

Finished Genome Sequence of Escherichia coli K-12 Strain HMS174 (ATCC 47011)

Mairhofer, J., Krempl, P., Thallinger, G. & Striedner, G., 2014, In : Genome Announcements. 2, 6, p. e00975-14-e00975-14

Research output: Contribution to journalArticleResearchpeer-review

Finished Genome Sequence of the Laboratory Strain Escherichia coli K-12 RV308 (ATCC 31608).

Krempl, P., Mairhofer, J., Striedner, G. & Thallinger, G., 2014, In : Genome Announcements. 2, 6, p. e00971-14-e00971-14

Research output: Contribution to journalArticleResearchpeer-review

Integrative omics analysis. A study based on Plasmodium falciparum mRNA and protein data.

Tomescu, O. A., Mattanovich, D. & Thallinger, G., 2014, In : BMC Systems Biology. 8, Suppl. 2, p. S4-S4

Research output: Contribution to journalArticleResearchpeer-review

NR4A1-mediated apoptosis supresses lymphomagenesis and is associated with a favorable cancer specific survival in patients with aggressive B-cell lymphomas

Deutsch, A., Rinner, B., Wenzl, K., Pichler, M., Troppan, K., Steinbauer, E., Schwarzenbacher, D., Reitter, S., Feichtinger, J., Tierling, S., Prokesch, A., Scheideler, M., Krogsdam, A., Thallinger, G., Schaider, H., Beham-Schmid, C. & Neumeister, P., 2014, In : Blood. 123, 15, p. 2367-2377

Research output: Contribution to journalArticleResearchpeer-review

Peroxidase gene discovery from the horseradish transcriptome

Näätsaari, L., Krainer, F., Schubert, M., Glieder, A. & Thallinger, G., 2014, In : BMC Genomics . 15, 1, p. 227-227

Research output: Contribution to journalArticleResearchpeer-review

Resolving tumor heterogeneity: genes involved in chordoma cell development identified by low-template analysis of morphologically distinct cells

El-Heliebi, A., Kroneis, T., Wagner, K., Meditz, K., Kolb, D., Feichtinger, J., Thallinger, G., Quehenberger, F., Liegl-Atzwanger, B. & Rinner, B., 2014, In : PLoS ONE. 9, 2, p. e87663-e87663

Research output: Contribution to journalArticleResearchpeer-review

Stenotrophomonas comparative genomics reveals genes and functions that differentiate beneficial and pathogenic bacteria

Alavi, M., Starcher, M., Thallinger, G., Zachow, C., Müller, H. & Berg, G., 2014, In : BMC Genomics . 151, p. 482-482

Research output: Contribution to journalArticleResearchpeer-review

The mzTab Data Exchange Format: communicating MS-based proteomics and metabolomics experimental results to a wider audience

Griss, J., Jones, A. R., Sachsenberg, T., Walzer, M., Laurent, G., Hartler, J., Thallinger, G., Salek, R. M., Steinbeck, C., Nadin, N., Cox, J., Neumann, S., Fan, J., Reisinger, F., Qing-Wei, X., del Toro, N., Perez-Riverol, Y., Ghali, F., Bandeira, N., Xenarios, I. & 3 othersKohlbacher, O., Vizcaino, J. A. & Henning, H., 2014, In : Molecular & cellular proteomics. 13, 10, p. 2765-2775

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The Sphagnum microbiome supports bog ecosystem functioning under extreme conditions.

Bragina, A., Oberauner-Wappis, L., Zachow, C., Halwachs, B., Thallinger, G., Müller, H. & Berg, G., 2014, In : Molecular ecology. 23, 18, p. 4489-4851

Research output: Contribution to journalArticleResearchpeer-review

Towards improved membrane protein production in Pichia pastoris: general and specific transcriptional response to membrane protein overexpression

Vogl, T., Thallinger, G., Zellnig, G., Drew, D., Cregg, J., Glieder, A. & Freigaßner, M. E., 2014, In : New biotechnology. 31, 6, p. 538-552

Research output: Contribution to journalArticleResearchpeer-review

Untargeted profiling of tracer-derived metabolites using stable isotopic labeling and fast polarity-switching LC-ESI-HRMS

Kluger, B., Bueschl, C., Neumann, N., Stückler, R., Doppler, M., Chassy, A. W., Waterhouse, A. L., Rechthaler, J., Kampleitner, N., Thallinger, G., Adam, G., Krska, R. & Schuhmacher, R., 2014, In : Analytical Chemistry. 86, 23, p. 11533-11537

Research output: Contribution to journalArticleResearchpeer-review

2013

A Bioinformatics Approach for Integrated Transcriptomic and Proteomic Comparative Analyses of Model and Non-sequenced Anopheline Vectors of Human Malaria Parasites.

Ubaida Mohien, C., Colquhoun, D., Mathias, D., Gibbons, J., Armistead, J., Rodriguez, M., Rodriguez, M., Edwards, N., Hartler, J., Thallinger, G., Graham, D., Martinez-Barnetche, J., Rokas, A. & Dinglasan, R., 2013, In : Molecular & cellular proteomics. 12, 1, p. 120-131

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Alterations in the colonic microbiota in response to osmotic diarrhea

Gorkiewicz, G., Thallinger, G., Trajanoski, S., Lackner, S., Stocker, G., Hinterleitner, T., Gülly, C. & Högenauer, C., 2013, In : PLoS ONE. 8, 2, p. e55817-

Research output: Contribution to journalArticleResearchpeer-review

Bioinformatics tools and challenges in structural analysis of lipidomics MS/MS data

Hartler, J., Tharakan, R., Köfeler, H., Graham, D. & Thallinger, G., 2013, In : Briefings in Bioinformatics. 14, 3, p. 375-390

Research output: Contribution to journalArticleResearchpeer-review