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Christiane Luley

Dipl.-Ing. Dr.techn.

20042017
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Research Output 2004 2015

2015

All-in-one assay for β-D-galactoside sialyltransferases: quantification of productive turnover, error hydrolysis and site selectivity

Czabany, T., Schmoelzer, K., Luley, C., Ribitsch, D. & Nidetzky, B., 2015, In : Analytical biochemistry. 483, p. 47-53

Research output: Contribution to journalArticleResearchpeer-review

Comparison of broad-scope assays of nucleotide sugar-dependent glycosyltransferases.

Czabany, T., Bubner, P., Luley, C. & Nidetzky, B., 2015, In : Analytical biochemistry. 490, p. 46-51

Research output: Contribution to journalArticleResearchpeer-review

Complete switch from alpha2,3- to alpha2,6-regioselectivity in Pasteurella dagmatis beta-D-galactoside sialyltransferase by active-site redesign

Schmoelzer, K., Czabany, T., Luley, C., Pavkov-Keller, T., Ribitsch, D., Schwab, H., Gruber, K., Weber, H. & Nidetzky, B., 10 May 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Complete switch from alpha2,3- to alpha2,6-regioselectivity in Pasteurella dagmatis beta-D-galactoside sialyltransferase by active-site redesign

Schmoelzer, K., Czabany, T., Luley, C., Pavkov-Keller, T., Ribitsch, D., Schwab, H., Gruber, K., Weber, H. & Nidetzky, B., 4 May 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Complete switch from α-2,3- to α-2,6-regioselectivity in Pasteurella dagmatis β-D-galactoside sialyltransferase by active-site redesign

Schmoelzer, K., Czabany, T., Luley, C., Pavkov-Keller, T., Ribitsch, D., Schwab, H., Gruber, K., Weber, H. & Nidetzky, B., 2015, In : Chemical Communications. p. 3083-3086

Research output: Contribution to journalArticleResearchpeer-review

Expression of human sialyltransferase in yeast

Czabany, T., Schmoelzer, K., Luley, C., Ribitsch, D., Schwab, H. & Nidetzky, B., 21 May 2015.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

N-​terminally truncated glycosyltransferases for use in post-​translational sialylation

Czabany, T., Engel, A., Greif, M., Jung, C., Luley, C., Malik, S., Mueller, R., Nidetzky, B., Ribitsch, D., Schmoelzer, K., Schwab, H., Sobek, H., Suppmann, B., Thomann, M. & Zitzenbacher, S., 8 Jan 2015, Patent No. WO 2015001034 A1

Research output: PatentResearch

Process for the mono- and bi-​sialylation of glycoproteins employing N-​terminally truncated β-​galactoside α-​2,​6-​sialyltransferase mutants

Czabany, T., Engel, A., Greif, M., Jung, C., Luley, C., Malik, S., Mueller, R., Nidetzky, B., Ribitsch, D., Schmoelzer, K., Schwab, H., Sobek, H., Suppmann, B., Thomann, M. & Zitzenbacher, S., 8 Jan 2015, Patent No. WO 2015001033 A1

Research output: PatentResearch

2014

A newly discovered multifunctional α2,3-sialyltransferase from Pasteurella dagmatis carries a natural Ser-to-Thr substitution

Luley, C., Schmoelzer, K., Ribitsch, D., Czabany, T., Deja Kokot, N. V., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 13 Feb 2014.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Characterization of a multifunctional α2,3-sialyltransferase from Pasteurella dagmatis, carrying a natural Ser-to-Thr substitution

Schmoelzer, K., Ribitsch, D., Czabany, T., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 2014.

Research output: Contribution to conferencePosterResearch

High-quality production of human α-2,6-sialyltransferase in Pichia pastoris requires control over N-terminal truncations by host-inherent protease activities

Ribitsch, D., Zitzenbacher, S., Augustin, P. A., Schmoelzer, K., Luley, C., Thomann, M., Jung, C., Sobek, H., Müller, R., Nidetzky, B. & Schwab, H., 2014, In : Microbial cell factories . 13, p. 138-149

Research output: Contribution to journalArticleResearchpeer-review

Mechanism and application of bacterial sialyltransferase

Czabany, T., Schmoelzer, K., Ribitsch, D., Luley, C., Schwab, H. & Nidetzky, B., 7 Sep 2014.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Mechanistic study of CMP-Neu5Ac hydrolysis by α2,3-sialyltransferase from Pasteurella dagmatis

Schmoelzer, K., Luley, C., Czabany, T., Ribitsch, D., Schwab, H., Weber, H. & Nidetzky, B., 2014, In : FEBS letters. 588, 25;17, p. 2978-2984

Research output: Contribution to journalArticleResearchpeer-review

2013

A newly discovered multifunctional alpha2,3-sialyltransferase from Pasteurella dagmatis carries a natural Ser-to-Thr substitution

Schmoelzer, K., Ribitsch, D., Czabany, T., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 7 Jul 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Open Access
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A newly discovered multifunctional α2,3-sialyltransferase from Pasteurella dagmatis PdST carries a natural Ser-to-Thr substitution

Czabany, T., Schmoelzer, K., Ribitsch, D., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 13 Oct 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

A newly discovered multifunctional α2,3-sialyltransferase from Pasteurella dagmatis PdST carries a natural Ser-to-Thr substitution

Schmoelzer, K., Ribitsch, D., Czabany, T., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 10 Sep 2013.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Characterization of a multifunctional alpha2,3-sialyltransferase from Pasteurella dagmatis, carrying a natural Ser-to-Thr substitution

Schmoelzer, K., Ribitsch, D., Czabany, T., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 2013.

Research output: Contribution to conferencePosterResearch

Characterization of a multifunctional α2,3-sialyltransferase from Pasteurella dagmatis

Schmoelzer, K., Ribitsch, D., Czabany, T., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 2013, In : Glycobiology. 23, 11, p. 1293-1304

Research output: Contribution to journalArticleResearchpeer-review

Characterization of a multifunctional α2,3-sialyltransferase from Pasteurella dagmatis, carrying a natural Ser-to-Thr substitution

Schmoelzer, K., Ribitsch, D., Czabany, T., Luley, C., Kokot, D., Lyskowski, A. F., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 2013.

Research output: Contribution to conferencePosterResearch

Rec. ST6Gal-I variants to control enzymatic activity in processes of in vitro glycoengineering

Engel, A. M., Sobek, H., Greif, M., Malik, S., Thomann, M., Jung, C., Reusch, D., Ribitsch, D., Zitzenbacher, S., Luley, C., Schmoelzer, K., Czabany, T., Nidetzky, B., Schwab, H. & Mueller, R., 2013.

Research output: Contribution to conferencePosterResearch

2012

A novel multifunctional sialyltransferase PdST from Pasteurella dagmatis

Schmoelzer, K., Kokot, D., Czabany, T., Luley, C., Ribitsch, D., Zitzenbacher, S., Augustin, P. A., Lyskowski, A. F., Nidetzky, B. & Schwab, H., 2 Jul 2012.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Enzymatic production of 2-O-(alpha-D-glucopyranosyl)-glycerate using sucrose phosphorylase

Goedl, C., Sawangwan, T. & Nidetzky, B., 18 Jul 2012, Patent No. EP 2186904

Research output: PatentResearch

Expression of mammalian glycosyltransferases in yeast

Ribitsch, D., Zitzenbacher, S., Augustin, P. A., Schmoelzer, K., Czabany, T., Luley, C., Nidetzky, B. & Schwab, H., 2012.

Research output: Contribution to conferencePosterResearch

Identification, cloning, expression and characterization of a novel multifunctional sialyltransferase from Pasteurella dagmatis

Schmoelzer, K., Kokot, D., Czabany, T., Luley, C., Ribitsch, D., Zitzenbacher, S., Augustin, P. A., Nidetzky, B. & Schwab, H., 2012.

Research output: Contribution to conferencePosterResearch

2011

Aromatic interactions at the catalytic subsite of sucrose phosphorylase: Analysis of their role in enzymatic glucosyl transfer

Wildberger, P., Luley, C. & Nidetzky, B., 3 Jul 2011.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Disaccharide phosphorylases: mechanistic diversity and applications in the glycosciences

Luley-Goedl, C. & Nidetzky, B., 2011, (Accepted/In press) Carbohydrate Modifying Biocatalysts. Singapore: .

Research output: Chapter in Book/Report/Conference proceedingChapterResearch

Glycosides as compatible solutes: bio-synthesis and application

Luley-Goedl, C. & Nidetzky, B., 2011, In : Natural products reports. 28, p. 875-896

Research output: Contribution to journalArticleResearchpeer-review

Novel High Throughput Screening Methodologies to Advance Directed Evolution of Glycosyltransferases

Bubner, P., Luley, C., Egger, S. & Nidetzky, B., 2011.

Research output: Contribution to conferencePosterResearch

Novel High Throughput Screening Methodologies to Advance Directed Evolution of Glycosyltransferases

Bubner, P., Luley, C., Egger, S. & Nidetzky, B., 15 Feb 2011.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Production of a hypothetical sialyltransferase from P. dagmatis: Cloning, expression, purification and setup of a screening assay

Schmoelzer, K., Czabany, T., Luley, C., Ribitsch, D., Zitzenbacher, S., Schwab, H. & Nidetzky, B., 2011.

Research output: Contribution to conferencePosterResearch

The role of aromatic interactions at the catalytic subsite of sucrose phosphorylase

Wildberger, P., Luley, C. & Nidetzky, B., 2011.

Research output: Contribution to conferencePosterResearch

The role of aromatic interactions in the catalytic mechanism of sucrose phosphorylase

Wildberger, P., Luley, C. & Nidetzky, B., 15 Feb 2011.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

2010

Biocatalytic process for production of alpha-glucosylglycerol using sucrose phosphorylase.

Luley-Goedl, C., Sawangwan, T., Mueller, M., Schwarz, A. & Nidetzky, B., 2010, In : Food technology and biotechnology. 48, 3, p. 276-283

Research output: Contribution to journalArticleResearchpeer-review

Carbohydrate synthesis by disaccharide phosphorylases: reactions, catalytic mechanisms and applications in the glycosciences

Nidetzky, B. & Luley, C., 2010, In : Biotechnology Journal. 5, p. 1324-1338

Research output: Contribution to journalArticleResearchpeer-review

Glucosylglycerol and glucosylglycerate as enzyme stabilizers

Sawangwan, T., Goedl, C. & Nidetzky, B., 2010, In : Biotechnology Journal. 5, p. 187-191

Research output: Contribution to journalArticleResearchpeer-review

Regioselective O-glucosylation by sucrose phosphorylase: a promising route for functional diversification of a range of 1,2-propanediols.

Luley-Goedl, C., Sawangwan, T., Brecker, L., Wildberger, P. & Nidetzky, B., 2010, In : Carbohydrate Research. 345, 12, p. 1736-1740

Research output: Contribution to journalArticleResearchpeer-review

Small-molecule glucosylation by sucrose phosphorylase: structure-activity relationships for acceptor substrates revisted.

Luley-Goedl, C. & Nidetzky, B., 2010, In : Carbohydrate Research. 345, 10, p. 1492-1496

Research output: Contribution to journalArticleResearchpeer-review

Small-molecule glucosylation using sucrose phosphorylase.

Nidetzky, B., Luley, C. & Sawangwan, T., 18 Mar 2010.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Substitution of the catalytic acid-base Glu237 by Gln suppresses hydrolysis during glucosylation of phenolic acceptors by Leuconostoc mesenteroides sucrose phosphorylase

Wiesbauer, J., Gödl, C., Schwarz, A., Brecker, L. & Nidetzky, B., 2010, In : Journal of molecular catalysis / B. 65, p. 24-29

Research output: Contribution to journalArticleResearchpeer-review

Sucrose phosphorylase: a powerful transglucosylation catalyst for synthesis of alpha-D-glucosides as industrial fine chemicals.

Goedl, C., Sawangwan, T., Wildberger, P. & Nidetzky, B., 2010, In : Biocatalysis and Biotransformation. 28, 1, p. 10-21

Research output: Contribution to journalArticleResearchpeer-review

Sucrose Phosphorylase in Carbohydrate Synthesis - Mechanistic and Synthetic Considerations

Gödl, C., Sawangwan, T., Wildberger, P. & Nidetzky, B., 2010.

Research output: Contribution to conferencePosterResearch

Tapping the Potential of a Biocatalyst: Industrial Scale Synthesis of Natural Products using Leuconostoc mesenteroides Sucrose Phosphorylase

Bubner, P., Luley, C., Sawangwan, T., Schwarz, A., Müller, M. & Nidetzky, B., 2010.

Research output: Contribution to conferencePosterResearch

The role of aromatic stacking interactions at Phe-52 in the catalytic mechansim of sucrose phosphorylase

Wildberger, P., Luley-Goedl, C. & Nidetzky, B., 2010.

Research output: Contribution to conferencePosterResearch

2009

2-O-(alpha-D-glucopyranosyl)-sn-glycerol I) Development of an efficient biocatalytic production process

Gödl, C., Sawangwan, T., Müller, M., Schwarz, A. & Nidetzky, B., 2009.

Research output: Contribution to conferencePosterResearch

2-O-(alpha-D-glucopyranosyl)-sn-glycerol II) Single-step chromatographic workup and exploitation as protein stabilizer

Sawangwan, T., Gödl, C., Müller, M., Schwarz, A. & Nidetzky, B., 2009.

Research output: Contribution to conferencePosterResearch

Biocatalytic process development for the synthesis of carbohydrate-based compatible solutes

Nidetzky, B., Gödl, C., Sawangwan, T. & Schwarz, A., 5 Jul 2009.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Disaccharide phosphorylases: from structure-function relationships to application in biocatalytic synthesis

Gödl, C., Sawangwan, T. & Nidetzky, B., 11 May 2009.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

Glucosyl transfer by retaining disaccharide phosphorylases: mechanistic studies and application in synthesis

Nidetzky, B., Gödl, C. & Sawangwan, T., 19 Jul 2009.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch

High-yielding biocatalytic process for the production of 2-O-(alpha-D-glucopyranosyl)-sn-glycerol, a natural osmolyte and useful moisturizing ingredient

Nidetzky, B., Sawangwan, T., Luley, C. & Müller, M., 22 Mar 2009.

Research output: Contribution to conference(Old data) Lecture or PresentationResearch