Christian Lembacher-Fadum

Dipl.-Ing., BSc

20152019
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Klebsiella oxytoca Medicine & Life Sciences
Prenylation Medicine & Life Sciences
Enterotoxins Medicine & Life Sciences
Post Translational Protein Processing Medicine & Life Sciences
Microtubules Medicine & Life Sciences
Labeling Chemical Compounds
Peptides Engineering & Materials Science
Cysteine Medicine & Life Sciences

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Research Output 2015 2019

Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities

Unterhauser, K., Pöltl, L., Schneditz, G., Kienesberger, S., Glabonjat, R. A., Kitsera, M., Pletz, J., Josa-Prado, F., Dornisch, E., Lembacher-Fadum, C., Roier, S., Gorkiewicz, G., Lucena, D., Barasoain, I., Kroutil, W., Wiedner, M., Loizou, J. I., Breinbauer, R., Díaz, J. F., Schild, S. & 2 othersHögenauer, C. & Zechner, E. L., 26 Feb 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3774-3783 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Klebsiella oxytoca
Enterotoxins
Microtubules
Colitis
Intestines

Labeling and Natural Post-Translational Modification of Peptides and Proteins via Chemoselective Pd-Catalyzed Prenylation of Cysteine

Schlatzer, T., Kriegesmann, J., Schröder, H., Trobe, M., Lembacher-Fadum, C., Santner, S., Kravchuk, A., Becker, C. F. W. & Breinbauer, R., 2019, In : Journal of the American Chemical Society. 141, 37, p. 14931-14937

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Prenylation
Post Translational Protein Processing
Labeling
Peptides
Cysteine

Pd-Mediated Allylation of Cysteine for Site-Selective Bioconjugation of Peptides and Proteins

Schlatzer, T., Kriegesmann, J., Schröder, H., Trobe, M., Lembacher-Fadum, C., Becker, C. F. W. & Breinbauer, R., 10 Sep 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Total Syntheses of Tilivalline and Tilimycin, Cytotoxic Secondary Metabolites of Klebsiella Oxytoca

Lembacher-Fadum, C., Dornisch, E., Pletz, J., Glabonjat, R. A., Martin, F., Neger, M., Högenauer, C., Francesconi, K. A., Kroutil, W., Zangger, K., Zechner, E. L. & Breinbauer, R., 27 Aug 2018.

Research output: Contribution to conferencePosterResearchpeer-review

Biosynthese des enterotoxischen Pyrrolobenzodiazepin-Naturstoffs Tilivallin

Dornisch, E., Pletz, J., Glabonjat, R. A., Martin, F., Lembacher-Fadum, C., Neger, M., Högenauer, C., Francesconi, K. A., Kroutil, W., Zangger, K., Breinbauer, R. & Zechner, E. L., 2017, In : Angewandte Chemie. 129, p. 14948–14952

Research output: Contribution to journalArticleResearchpeer-review

Open Access