Research Center Pharmaceutical Engineering (RCPE) (98888)

  • 8010

    Inffeldgasse 13 Graz

    Austria

Research Output 1991 2020

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2014

Investigation of Migrant-Polymer Interaction in Pharmaceutical Packaging Material using the Linear Interaction Energy Algorithm

Feenstra, P., Brunsteiner, M. & Khinast, J., 2014, In : Journal of Pharmaceutical Sciences . 103, 10, p. 3197-3204

Research output: Contribution to journalArticleResearchpeer-review

Low-dose capsule filling of inahalation produtcs: critical material attributes and process parameters

Faulhammer, E., Llusa, M., Khinast, J., Fink, M., Lawrence, S. M., Calzolari, V. & Biserni, S., 2014, In : International Journal of Pharmaceutics. 473, 1-2, p. 617–626

Research output: Contribution to journalArticleResearchpeer-review

Mechanistic modeling of modular co-rotating twin-screw extruders.

Eitzlmayr, A., Koscher, G., Reynolds, G., Huang, Z., Booth, J., Shering, P. & Khinast, J., 2014, In : International Journal of Pharmaceutics. 474, p. 157-176

Research output: Contribution to journalArticleResearchpeer-review

Modeling a seeded continuous crystallizer for the production of active pharmaceutical ingredients

Besenhard, M., Hohl, R., Hodzic, A., Eder, R. J. P. & Khinast, J., 2014, In : Crystal research and technology. 49, 2-3, p. 92-108

Research output: Contribution to journalArticleResearchpeer-review

Nano-extrusion: A promising tool for continuous manufacturing of solid nano-formulations

Baumgartner, R., Eitzlmayr, A., Matsko, N., Tetyczka, C., Khinast, J. & Roblegg, E., 2014, In : International Journal of Pharmaceutics. 477, 1-2, p. 1-11

Research output: Contribution to journalArticleResearchpeer-review

Near infrared light spectroscopy: Applicability and new developments

Scheibelhofer, O., Sacher, S. & Khinast, J., 2014, In : European pharmaceutical review. 19, 1, p. 51-55

Research output: Contribution to journalArticleResearch

Optical coherence tomography: An Alternative Methodology to Monitor Pharmaceutical Coating Processes

Markl, D., Sacher, S. & Khinast, J., 2014, In : GIT laboratory journal Europe. 7, p. 17-22

Research output: Contribution to journalArticleResearch

Optical coherence tomography as a novel tool for in-line monitoring of a pharmaceutical film-coating process

Markl, D., Hannesschläger, G., Sacher, S., Leitner, M. & Khinast, J., 2014, In : European Journal of Pharmaceutical Sciences. 55, p. 58-67

Research output: Contribution to journalArticleResearchpeer-review

Particular Film Formation of Phenytoin at Silica Surfaces.

Werzer, O., Baumgartner, R., Zawodzki, M. & Roblegg, E., 2014, In : Molecular pharmaceutics. 11, p. 610-616

Research output: Contribution to journalArticleResearchpeer-review

PAT for Tableting: Inline Monitoring of API and Excipients via NIR Spectroscopy

Wahl, P., Fruhmann, G., Sacher, S., Straka, G., Sebastian, S. & Khinast, J., 2014, In : European journal of pharmaceutics and biopharmaceutics. 87;2, p. 271-278

Research output: Contribution to journalArticleResearchpeer-review

Structural and Dynamic Properties of Amorphous Solid Dispersions: The Role of Solid‐State Nuclear Magnetic Resonance Spectroscopy and Relaxometry

Paudel, A., Geppi, M. & Van den Mooter, G., 8 Apr 2014, In : Journal of Pharmaceutical Sciences .

Research output: Contribution to journalArticleResearchpeer-review

Magnetic Resonance Spectroscopy
Crystallization
Pharmaceutical Preparations
Solubility
Biological Availability

Surface modified glass beads as model carriers in dry powder inhalers—Influence of drug load on the fine particle fraction

Zellnitz, S., Schröttner, H. & Urbanetz, N. A., 2014, In : Powder Technology. 268, p. 377-386

Research output: Contribution to journalArticleResearchpeer-review

The design of controlled-release formulations resistant to alcohol-induced dose dumping – A review

Jedinger, N., Khinast, J. & Roblegg, E., 2014, In : European journal of pharmaceutics and biopharmaceutics. 87, p. 217-226

Research output: Contribution to journalArticleResearchpeer-review

The effects of material attributes on capsule fill weight and weight variability in dosator nozzle machines.

Faulhammer, E., Llusa, M., Khinast, J., Scheibelhofer, O., Radeke, C., Lawrence, S. M., Calzolari, V. & Biserni, S., 2014, In : International Journal of Pharmaceutics. p. 332-338

Research output: Contribution to journalArticleResearchpeer-review

The effects of powder compressibility, speed of capsule filling and pre-compression on plug densification

Llusa, M., Faulhammer, E., Khinast, J., Lawrence, S., Calzolari, V. & Biserni, S., 2014, In : International Journal of Pharmaceutics. 471, 1-2, p. 182-188

Research output: Contribution to journalArticleResearchpeer-review

Towards the optimisation and adaptation of dry powder inhalers

Cui, Y., Schmalfuß, S., Zellnitz, S., Urbanetz, N. A. & Sommerfeld, M., 2014, In : International Journal of Pharmaceutics. 470, p. 120-132

Research output: Contribution to journalArticleResearchpeer-review

Use of mechanistic simulations as a quantitative risk-ranking tool within the quality by design framework

Stocker, E., Toschkoff, G., Sacher, S. & Khinast, J., 2014, In : International Journal of Pharmaceutics. 475, 1-2, p. 245–255

Research output: Contribution to journalArticleResearchpeer-review

2013

Analysis of the wall mass transfer on spinning disks using an integral boundary layer method

Prieling, D. & Steiner, H., 2013, In : Chemical Engineering Science. 101, p. 109-119

Research output: Contribution to journalArticleResearchpeer-review

Characterization of a Laboratory-Scale Container for Freezing Protein Solutions with Detailed Evaluation of a Freezing Process Simulation

Rößl, U., Jajcevic, D., Leitgeb, S., Khinast, J. & Nidetzky, B., 2013, In : Journal of Pharmaceutical Sciences . 103, 2, p. 417-426

Research output: Contribution to journalArticleResearchpeer-review

Das Drucken patientenspezifischer pharmazeutischer Formulierungen - Technischer Ansatz für zukünftige Anwendungen

Fraser, S., Gruber, M., Khinast, J., Bauer, W., Brenn, G. & Zimmer, A., 2013, In : TechnoPharm. 3, 5, p. 246-252

Research output: Contribution to journalArticleResearch

Experimental Characterization and Modeling of Twin-Screw Extruder Elements for Pharmaceutical Hot Melt Extrusion

Eitzlmayr, A., Hörl, G., Koscher, G., Reynolds, G., Huang, Z., Booth, J., Shering, P. & Khinast, J., 2013, In : AIChE Journal. 59, 11, p. 4440-4450

Research output: Contribution to journalArticleResearchpeer-review

Impact of heat treatment and spray drying on cellular properties and culturability of Bifidobacterium bifidum BB-12

Wu, S., Salar-Behzadi, S., Tögel, S., Hofrichter, M., Altenburger, I., Unger, F., Wirth, M. & Viernstein, H., 2013, In : Food research international. 54, p. 93-101

Research output: Contribution to journalArticleResearchpeer-review

Inline monitoring and a PAT strategy for pharmaceutical hot melt extrusion

Wahl, P., Treffer, D. F., Mohr, S., Roblegg, E., Koscher, G. & Khinast, J., 2013, In : International Journal of Pharmaceutics. 455, p. 159-168

Research output: Contribution to journalArticleResearchpeer-review

Large-scale CFD–DEM simulations of fluidized granular systems

Jajcevic, D., Siegmann, E., Radeke, C. & Khinast, J., 19 Jul 2013, In : Chemical Engineering Science.

Research output: Contribution to journalArticleResearchpeer-review

Method to study the effect of blend flowability on the homogeneity of acetaminophen

Llusa, M., Pingali, K. & Muzzio, F. J., 2013, In : Drug development and industrial pharmacy. 39, 2, p. 252-258

Research output: Contribution to journalArticleResearchpeer-review

Monitoring Blending of Pharmaceutical Powders with Multipoint NIR Spectroscopy

Scheibelhofer, O., Balak, N., Wahl, P., Koller, D. M., Glasser, B. J. & Khinast, J., 2013, In : AAPS PharmSciTech . 14, 1, p. 234-244

Research output: Contribution to journalArticleResearchpeer-review

Preparation and characterization of physically modified glass beads used as model carriers in dry powder inhalers

Zellnitz, S., Redlinger-Pohn, J. D., Kappl, M., Urbanetz, N. A. & Schröttner, H., 2013, In : International Journal of Pharmaceutics. 447, p. 132-138

Research output: Contribution to journalArticleResearchpeer-review

Spatially resolved monitoring of powder mixing processes via multiple NIR-probes

Scheibelhofer, O., Balak, N., Koller, D. M. & Khinast, J., 2013, In : Powder Technology. 243, p. 161-170

Research output: Contribution to journalArticleResearchpeer-review

Spray drying of aqueous salbutamol sulfate solutions using the Nano Spray Dryer B-90 – The impact of process parameters on particle size

Zellnitz, S., Littringer, E. M., Hammernik, K., Adamer, V., Friedl, H. & Urbanetz, N. A., 2013, In : Drying technology. 31, 12, p. 1346-1353

Research output: Contribution to journalArticleResearchpeer-review

Structure based descriptors for the estimation of colloidal interactions and protein aggregation propensities

Brunsteiner, M., Flock, M. & Nidetzky, B., 2013, In : PLoS ONE. 8, 4, p. e59797-e59797

Research output: Contribution to journalArticleResearchpeer-review

Supervisory Control System for Monitoring a Pharmaceutical Hot Melt Extrusion Process

Markl, D., Wahl, P., Menezes, J. C., Koller, D. M., Kavsek, B., Francois, K., Roblegg, E. & Khinast, J., 2013, In : AAPS PharmSciTech . 14, 2, p. 1-11

Research output: Contribution to journalArticleResearchpeer-review

The effect of capsule-filling machine vibrations on average fill weight

Llusa, M., Faulhammer, E., Khinast, J., Lawrence, S., Biserni, S. & Calzolari, V., 2013, In : International Journal of Pharmaceutics. 454, 1, p. 381–387

Research output: Contribution to journalArticleResearchpeer-review

The Influence of Process Parameters on the Properties of PLGA-Microparticles Produced by the Emulsion Extraction Method

Kiss, N., Brenn, G., Suzzi, D., Scheler, S., Jennewein, H., Wieser, J. & Khinast, J., 2013, In : AIChE Journal. 59, 6, p. 1868-1881

Research output: Contribution to journalArticleResearchpeer-review

Thinking Continuously: A Microreactor for the Production and Scale-up of Biodegradable, Self-assembled Nanoparticles

Petschacher, C., Eitzlmayr, A., Besenhard, M., Wagner, J., Barthelmes, J., Bernkop-Schnürch, A., Khinast, J. & Zimmer, A., 2013, In : Polymer Chemistry. 4, p. 2342-2352

Research output: Contribution to journalArticleResearchpeer-review

Unsteady thin film flow on spinning disks at large Ekman numbers using an integral boundary layer method

Prieling, D. & Steiner, H., 2013, In : International journal of heat and mass transfer. p. 10-22

Research output: Contribution to journalArticleResearchpeer-review

2012

A new Textile-Based Approach to Assess the Antimicrobial Activity of Volatiles

Liebminger, S., Aichner, M., Oberauner-Wappis, L., Fürnkranz-Tuvshintugs, M., Cardinale, M. & Berg, G., 2012, In : Textile research journal. 82, 5, p. 484-491

Research output: Contribution to journalArticleResearchpeer-review

Arising of electrostatic charge in the mixing process and its influencing factors

Karner, S. & Urbanetz, N. A., 2012, In : Powder Technology. p. 261-268

Research output: Contribution to journalArticleResearchpeer-review

Binary collisions of drops of immiscible liquids

Roisman, I. V., Planchette, C., Lorenceau, E. & Brenn, G., 2012, In : Journal of fluid mechanics. 690, p. 512-535

Research output: Contribution to journalArticleResearchpeer-review

Continuous Sonocrystallization of Acetylsalicylic Acid (ASA): Control of Crystal Size

Eder, R. J-P., Schrank, S., Besenhard, M., Roblegg, E., Gruber-Wölfler, H. & Khinast, J., 2012, In : Crystal growth & design. 12, 10, p. 4733–4738

Research output: Contribution to journalArticleResearchpeer-review

DEM simulation of continuous tablet coating: Effects of tablet shape and fill level on inter-tablet coating variability

Suzzi, D., Toschkoff, G., Radl, S., Machold, D., Fraser, S., Glasser, B. J. & Khinast, J., 2012, In : Chemical Engineering Science. 69, p. 107-121

Research output: Contribution to journalArticleResearchpeer-review

Detailed analysis of air flow and spray loss in a pharmaceutical coating process

Toschkoff, G., Suzzi, D., Tritthart, W., Reiter, F., Schlingmann, M. & Khinast, J., 2012, In : AIChE Journal. 58, 2, p. 399-411

Research output: Contribution to journalArticleResearchpeer-review

Effect of process variables on the Small and Wide Angle X-ray Scattering (SWAXS) patterns of powders, granules and pharmaceutical tablets

Hodzic, A., Llusa, M., Heigl, N., Tritthart, W., Fraser, S., Laggner, P. & Khinast, J., 2012, In : Powder Technology. 221, 221, p. 447-452

Research output: Contribution to journalArticleResearchpeer-review

Effect of protamine on the solubility and deamidation of human growth hormone

Ablinger, E., Wegscheider, S., Keller, W., Prassl, R. & Zimmer, A., 2012, In : International Journal of Pharmaceutics. 427, p. 209-216

Research output: Contribution to journalArticleResearchpeer-review

Homogene Produkteigenschaften in der Sprühtrocknung durch laminare Rotationszerstäubung

Mescher, A., Littringer, E. M., Paus, R., Urbanetz, N. A. & Walzel, P., 2012, In : Chemie - Ingenieur - Technik. 1, p. 1-1

Research output: Contribution to journalArticleResearchpeer-review

Ibuprofen-Loaded Calcium Stearate Pellets: Drying-Induced Variations in Dosage Form Properties

Schrank, S., Hodzic, A., Zimmer, A., Glasser, B. J., Khinast, J. & Roblegg, E., 2012, In : AAPS PharmSciTech . 13, 2, p. 686-698

Research output: Contribution to journalArticleResearchpeer-review

Identification and molecular interpretation of the effects of drug incorporation on the self-emulsification process using spectroscopic, micropolarimetric and microscopic measurements

Mercuri, A., Peter, B., Paul, R. & Susan, B., 2012, In : Molecular pharmaceutics. 9, 9, p. 2658-2668

Research output: Contribution to journalArticleResearchpeer-review