Research Center Pharmaceutical Engineering (RCPE) (98888)

  • 8010

    Inffeldgasse 13 Graz

    Austria

Research Output 1991 2020

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Accuracy of micro powder dosing via a vibratory sieve–chute system

Besenhard, M., Faulhammer, E., Fathollahi, S., Reif, G., Calzolari, V., Biserni, S., Lawrence, S., Llusa, M. & Khinast, J., 2015, In : European journal of pharmaceutics and biopharmaceutics. 94, p. 264-272

Research output: Contribution to journalArticleResearchpeer-review

A combined DEM & FEM approach for modelling roll compaction process

Mazor, A., Orefice, L., Michrafy, A., de Ryck, A. & Khinast, J. G., Sep 2018, In : Powder Technology. 337, p. 3-16 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Rolls (machine components)
Finite difference method
Compaction
Powders
Finite element method

A Continuous Operation Concept for a Rotary Tablet Press Using Mass Flow Operating Points

Martinetz, M., Rehrl, J., Aigner, I., Sacher, S. & Khinast, J., 12 May 2017, In : Chemie - Ingenieur - Technik. 89, 8

Research output: Contribution to journalArticleResearchpeer-review

Adsorption-driven tuning of the electrical resistance of nanoporous gold

Wahl, P., Traußnig, T., Landgraf, S., Jin, H-J., Weissmüller, J. & Würschum, R., 2010, In : Journal of Applied Physics. 8, p. 073706-1-073706-6

Research output: Contribution to journalArticleResearchpeer-review

Adult rat retinal ganglion cells and glia can be printed by piezoelectric inkjet printing

Lorber, B., Hsiao, W-K., Hutchings, I. M. & Martin, K. R., Mar 2014, In : Biofabrication. 6, 1, p. 015001

Research output: Contribution to journalArticleResearchpeer-review

Printing
Retinal Ganglion Cells
Neuroglia
Regenerative Medicine
Cell Survival

Advances in experimental and mechanistic computational models to understand pulmonary exposure to inhaled drugs

Bäckman, P., Arora, S., Couet, W., Forbes, B., de Kruijf, W. & Paudel, A., 15 Feb 2018, In : European Journal of Pharmaceutical Sciences. 113, p. 41-52 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Inhalation Exposure
Computer Simulation
Lung
Pharmaceutical Preparations
Aerosols

Alcohol dose dumping: The influence of ethanol on hot-melt extruded pellets comprising solid lipids

Jedinger, N., Schrank, S., Mohr, S., Feichtinger, A., Khinast, J. & Roblegg, E., 2015, In : European journal of pharmaceutics and biopharmaceutics. 92, p. 83-95

Research output: Contribution to journalArticleResearchpeer-review

A model for the non-isothermal drying of particle-laden pastes

Brenn, G., Steiner, H., Kondor, I., Planchette, C., Mercuri, A. & Scharrer, G., 2016, In : International journal of heat and mass transfer. 92, p. 558-571

Research output: Contribution to journalArticleResearchpeer-review

A multivariate process monitoring strategy and control concept for a small-scale fermenter in a PAT environment

Besenhard, M. O., Scheibelhofer, O., François, K., Joksch, M. & Kavsek, B., 1 Oct 2018, In : Journal of Intelligent Manufacturing. 29, 7, p. 1501-1514 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Fermenters
Process monitoring
Process control
Fermentation
Yeast

Analysis of Flow and Mixing in Screw Elements of Corotating Twin-Screw Extruders via SPH

Eitzlmayr, A., Matic, J. & Khinast, J., Jun 2017, In : AIChE Journal. 63, 6, p. 2451-2463

Research output: Contribution to journalArticleResearchpeer-review

Extruders
Hydrodynamics
Conveying
Pressure
Geometry

Analysis of the wall mass transfer on spinning disks using an integral boundary layer method

Prieling, D. & Steiner, H., 2013, In : Chemical Engineering Science. 101, p. 109-119

Research output: Contribution to journalArticleResearchpeer-review

Analytical Solution for Thermal Transport in Packed Beds with Volumetric Heat Source

Salehi, M., Askarishahi, M. & Radl, S., 20 Jan 2017, In : Chemical Engineering Journal. 316, p. 131-136

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Packed beds
heat source
Fluids
fluid
temperature profile

An evaluation of the gliding performance of solid oral dosage form film coatings using an artificial mucous layer

Drumond, N. & Stegemann, S., 1 May 2019, In : Colloids and Surfaces B: Biointerfaces. 177, p. 235-241 7 p.

Research output: Contribution to journalArticleResearchpeer-review

gliding
Dosage Forms
Polymers
coatings
Polymer films

A new Textile-Based Approach to Assess the Antimicrobial Activity of Volatiles

Liebminger, S., Aichner, M., Oberauner-Wappis, L., Fürnkranz-Tuvshintugs, M., Cardinale, M. & Berg, G., 2012, In : Textile research journal. 82, 5, p. 484-491

Research output: Contribution to journalArticleResearchpeer-review

An Integrated Quality by Design (QbD) Approach towards Design Space Definition of a Blending Unit Operation by Discrete Element Method (DEM) Simulation

Adam, S., Suzzi, D., Radeke, C. & Khinast, J., 2011, In : European Journal of Pharmaceutical Sciences. 42, 1-2, p. 106–115

Research output: Contribution to journalArticleResearchpeer-review

An investigation of the hydrodynamic similarity of single-spout fluidized beds using CFD-DEM simulations

Ebrahimi, M., Siegmann, E., Prieling, D., Glasser, B. J. & Khinast, J. G., Oct 2017, In : Advanced powder technology. 28, 10, p. 2465-2481

Research output: Contribution to journalArticleResearchpeer-review

An in vitro–in vivo correlation study for nifedipine immediate release capsules administered with water, alcoholic and non-alcoholic beverages: Impact of in vitro dissolution media and hydrodynamics

Mercuri, A., Fares, R., Bresciani, M. & Nikoletta, F., 2016, In : International Journal of Pharmaceutics. 499, 1-2, p. 330-342

Research output: Contribution to journalArticleResearchpeer-review

A novel assay for the detection of bioactive volatiles evaluated by screening of lichen-associated bacteria

Cernava, T., Aschenbrenner, I. A., Grube, M., Liebminger, S. & Berg, G., 2015, In : Frontiers in Microbiology . 6, p. 398

Research output: Contribution to journalArticleResearchpeer-review

Volatile Organic Compounds
Lichens
Bacteria
Stenotrophomonas
Growth

A novel in silico scale-up approach for hot melt extrusion processes

Matic, J., Witschnigg, A., Zagler, M., Eder, S. & Khinast, J., 31 Aug 2019, In : Chemical Engineering Science. 204, p. 257-269

Research output: Contribution to journalArticleResearchpeer-review

A novel method for modeling of complex wall geometries in smoothed particle hydrodynamics

Eitzlmayr, A., Koscher, G. & Khinast, J., 2014, In : Computer physics communications. 185, 10, p. 2436-2448

Research output: Contribution to journalArticleResearchpeer-review

A numerical investigation into the effect of angular particle shape on blast furnace burden topography and percolation using a GPU solved discrete element model

Govender, N., Wilke, D. N., Wu, C-Y., Tuzun, U. & Kureck, H. G., 31 Aug 2019, In : Chemical Engineering Science. p. 9-26 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Polydispersity
Blast furnaces
Topography
Coke
Ores

Apoprotein-phospholipid interactions in Lp(a)

Hermetter, A., Sommer, A., Gorges, R., Prenner, E., Kostner, G. M. & Paltauf, F., 1994, In : Chemistry and Physics of Lipids. 67-68, p. 115-119

Research output: Contribution to journalArticleResearchpeer-review

A Review of PAT Strategies in Secondary Solid Oral Dosage Manufacturing of Small Molecules

Laske, S., Paudel, A., Scheibelhofer, O., Sacher, S., Hörmann, T. & Khinast, J., Mar 2017, In : Journal of Pharmaceutical Sciences . 106, 3, p. 667-712 45 p.

Research output: Contribution to journalArticleResearchpeer-review

Technology
Pharmaceutical Preparations
Pressure
Temperature
Research

Arising of electrostatic charge in the mixing process and its influencing factors

Karner, S. & Urbanetz, N. A., 2012, In : Powder Technology. p. 261-268

Research output: Contribution to journalArticleResearchpeer-review

Arzneimitteltherapie und Therapietreue älterer Menschen in ärztlicher und zahnärztlicher Behandlung.

Stegemann, S., 2015, In : Zeitschrift für Senioren-Zahnmedizin. 3, 2, p. 67-71

Research output: Contribution to journalArticleResearchpeer-review

A Schrödinger-Poisson-Boltzmann system applied to the charge carrier transport in strained silicon

Toschkoff, G., Ossig, G., Lichtenberger, P., Zojer, K. & Schürrer, F., 2010, In : Il nuovo cimento della Società Italiana di Fisica / C. 33 C, 1, p. 239-246

Research output: Contribution to journalArticleResearchpeer-review

Assessment of Dry Powder Inhaler Carrier Targeted Design: A Comparative Case Study of Diverse Anomeric Compositions and Physical Properties of Lactose

Pinto, J. T., Zellnitz, S., Guidi, T., Roblegg, E. & Paudel, A., 1 Jun 2018, In : Molecular pharmaceutics. 15, 7, p. 2827-2839

Research output: Contribution to journalArticleResearchpeer-review

Dry Powder Inhalers
Lactose
Adhesives
Gas Lasers
Surface Properties

At-line validation of optical coherence tomography as in-line/at-line coating thickness measurement method

Wolfgang, M., Peter, A., Wahl, P., Markl, D., Zeitler, J. A. & Khinast, J. G., 15 Dec 2019, In : International Journal of Pharmaceutics. 572

Research output: Contribution to journalArticleResearchpeer-review

Automatic correction for window fouling of near infrared probes in fluidised systems

Scheibelhofer, O., Hohl, R., Salar-Behzadi, S., Haack, D., Koch, K., Kerschhaggl, P., Sacher, S., Menezes, J. C. & Khinast, J., 2014, In : Journal of near infrared spectroscopy. 22, 3, p. 229-238

Research output: Contribution to journalArticleResearchpeer-review

Bending modulus of bidisperse rafts: Local and collective contributions

Petit, P., Biance, A-L., Lorenceau, E. & Planchette, C., 2016, In : Physical review / E. 93, p. 042802

Research output: Contribution to journalArticleResearchpeer-review

Binary collisions of drops of immiscible liquids

Roisman, I. V., Planchette, C., Lorenceau, E. & Brenn, G., 2012, In : Journal of fluid mechanics. 690, p. 512-535

Research output: Contribution to journalArticleResearchpeer-review

Biotransformations in microstructured reactors: more than flowing with the stream?

Bolivar, J. M., Wiesbauer, J. & Nidetzky, B., 2011, In : Trends in biotechnology. 29, 7, p. 333-342

Research output: Contribution to journalArticleResearchpeer-review

Calibration-free in-line monitoring of pellet coating processes via optical coherence tomography

Markl, D., Zettl, M., Hannesschläger, G., Sacher, S., Leitner, M., Buchsbaum, A. & Khinast, J., 2015, In : Chemical Engineering Science. 125, p. 200-208

Research output: Contribution to journalArticleResearchpeer-review

Can we predict trends in tribo-charging of pharmaceutical materials from first principles?

Brunsteiner, M., Zellnitz, S., Pinto, J. T., Karrer, J. & Paudel, A., 1 Nov 2019, In : Powder Technology. 356, p. 892-898 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Ionization potential
Drug products
Pharmaceutical Preparations
Discrete Fourier transforms
Electronic structure
Lactose
Powders
Inhalation
Capsules
Mannitol

Carrier-free enzyme immobilization for biocatalysis

Rößl, U., Nahalka, J. & Nidetzky, B., 2010, In : Biotechnology Letters. 32, p. 341-350

Research output: Contribution to journalArticleResearchpeer-review

Characterization of a Laboratory-Scale Container for Freezing Protein Solutions with Detailed Evaluation of a Freezing Process Simulation

Rößl, U., Jajcevic, D., Leitgeb, S., Khinast, J. & Nidetzky, B., 2013, In : Journal of Pharmaceutical Sciences . 103, 2, p. 417-426

Research output: Contribution to journalArticleResearchpeer-review

Characterization of the coating and tablet core roughness by means of 3D optical coherence tomography

Khinast, J., Markl, D., Wahl, P., Pichler, H. & Sacher, S., 2018, In : International Journal of Pharmaceutics. p. 459-466

Research output: Contribution to journalArticleResearchpeer-review

Coating of glass substrates to prevent alkali ion diffusion into pharmaceutical solutions

Schweiger, S., Neubauer, C., Fraser, S., Klein, T., Schennach, R., Reichmann, A. & Gruber-Wölfler, H., 2014, In : Surface & coatings technology. 258, p. 1249-1255

Research output: Contribution to journalArticleResearchpeer-review

Comparing particle size distributions of an arbitrary shape

Scheibelhofer, O., Besenhard, M., Piller, M. & Khinast, J., 16 Feb 2016, In : Powder Technology. 294, p. 134-145

Research output: Contribution to journalArticleResearchpeer-review

Comparison of video analysis and simulations of a drum coating process

Boehling, P., Toschkoff, G., Dreu, R., Just, S., Kleinebudde, P., Funke, A., Rehbaum, H. & Khinast, J. G., 15 Jun 2017, In : European Journal of Pharmaceutical Sciences. 104, p. 72-81 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Tablets
Drug Industry
Mechanics

Computational Fluid Dynamics-Discrete Element Method Modeling of an Industrial-Scale Wurster Coater

Boehling, P., Khinast, J. G., Jajcevic, D., Davies, C., Carmody, A., Doshi, P., Ende, M. T. A. & Sarkar, A., Jan 2019, In : Journal of Pharmaceutical Sciences . 108, 1, p. 538-550

Research output: Contribution to journalArticleResearchpeer-review

Condensation Reaction between Carbohydrazide and Salicylaldehyde: in-line Vibrational Spectroscopy Monitoring and Characterization of the Reaction Products in Solution and Solid State

Jednačak, T., Novak, P., Hodzic, A., Scheibelhofer, O., Khinast, J., Plavec, J., Primož, Š. & Vuković, J. P., 2014, In : Acta chimica Slovenica. 61, 1, p. 161-169

Research output: Contribution to journalArticleResearch

Continuous API-crystal coating via coacervation in a tubular reactor

Besenhard, M., Hohl, R., Thurnberger, A., Faulhammer, E. & Khinast, J., 2014, In : International Journal of Pharmaceutics. 475, p. 198-207

Research output: Contribution to journalArticleResearchpeer-review

Continuous Drying of Pharmaceutical Powders Using a Twin-Screw Extruder

Kreimer, M., Aigner, I., Lepek, D. & Khinast, J., 20 Jul 2018, In : Organic Process Research and Development. 22, 7, p. 813-823 11 p.

Research output: Contribution to journalArticleResearchpeer-review

screws
Extruders
Powders
drying
Drying

Continuous Drying of Small Particles for Pharmaceutical Applications – An Evaluation of Selected Labscale Systems

Gursch, J., Hohl, R., Armenante, M., Dujmovic, D., van der Wel, P., Brozio, J., Krumme, M., Rasenack, N. & Khinast, J., 2015, In : Organic process research & development. 19, 12, p. 2055-2066

Research output: Contribution to journalArticleResearchpeer-review

Continuous feeding of low-dose APIs via periodic micro dosing

Faulhammer, E., Khinast, J. & Fathollahi, S., 17 May 2016, In : International Journal of Pharmaceutics.

Research output: Contribution to journalArticleResearchpeer-review